nifedipine-1814 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the nifedipine-1814 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAM10 ADAM metallopeptidase domain 10
AKR1C2 aldo-keto reductase family 1, member C2
AMIGO2 adhesion molecule with Ig-like domain 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
APOL2 apolipoprotein L, 2
APOL6 apolipoprotein L, 6
ATM ATM serine/threonine kinase
ATP13A3 ATPase type 13A3
ATXN7L3B ataxin 7-like 3B
BAG3 BCL2-associated athanogene 3
BBS4 Bardet-Biedl syndrome 4
BMP2 bone morphogenetic protein 2
BRWD1 bromodomain and WD repeat domain containing 1
C10ORF10 chromosome 10 open reading frame 10
CASP8AP2 caspase 8 associated protein 2
CCNG2 cyclin G2
CDK17 cyclin-dependent kinase 17
CLGN calmegin
CNOT4 CCR4-NOT transcription complex, subunit 4
CRYAB crystallin, alpha B
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DAZAP2 DAZ associated protein 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EGR1 early growth response 1
ETV5 ets variant 5
FAM178A family with sequence similarity 178, member A
FANCF Fanconi anemia, complementation group F
FCF1 FCF1 rRNA-processing protein
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GEMIN4 gem (nuclear organelle) associated protein 4
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HS1BP3 HCLS1 binding protein 3
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER5 immediate early response 5
IQCG IQ motif containing G
ISL1 ISL LIM homeobox 1
JAK2 Janus kinase 2
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIAA0319L KIAA0319-like
KRCC1 lysine-rich coiled-coil 1
KRT4 keratin 4, type II
LEPROT leptin receptor overlapping transcript
LYPD3 LY6/PLAUR domain containing 3
MAPK7 mitogen-activated protein kinase 7
MATR3 matrin 3
MBD4 methyl-CpG binding domain protein 4
MED28 mediator complex subunit 28
MEX3D mex-3 RNA binding family member D
MICALL1 MICAL-like 1
MPDZ multiple PDZ domain protein
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTMR1 myotubularin related protein 1
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
N4BP1 NEDD4 binding protein 1
N4BP2L2 NEDD4 binding protein 2-like 2
NCKAP1 NCK-associated protein 1
NIPAL3 NIPA-like domain containing 3
NNT nicotinamide nucleotide transhydrogenase
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAPOLA poly(A) polymerase alpha
PGAP1 post-GPI attachment to proteins 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRSS22 protease, serine, 22
PSAT1 phosphoserine aminotransferase 1
PTPRE protein tyrosine phosphatase, receptor type, E
RAD52 RAD52 homolog (S. cerevisiae)
RBM7 RNA binding motif protein 7
RDX radixin
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SATB2 SATB homeobox 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TM2D1 TM2 domain containing 1
TMCO6 transmembrane and coiled-coil domains 6
TPD52L1 tumor protein D52-like 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM2 tripartite motif containing 2
TRIO trio Rho guanine nucleotide exchange factor
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBGCP3 tubulin, gamma complex associated protein 3
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2H ubiquitin-conjugating enzyme E2H
USP34 ubiquitin specific peptidase 34
ZNF177 zinc finger protein 177
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AMPD2 adenosine monophosphate deaminase 2
ARHGAP11A Rho GTPase activating protein 11A
ASTE1 asteroid homolog 1 (Drosophila)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCAS3 breast carcinoma amplified sequence 3
BTBD2 BTB (POZ) domain containing 2
C1R complement component 1, r subcomponent
C7ORF43 chromosome 7 open reading frame 43
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CGREF1 cell growth regulator with EF-hand domain 1
CLDN15 claudin 15
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
COQ4 coenzyme Q4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DTWD1 DTW domain containing 1
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EFNB1 ephrin-B1
ELP3 elongator acetyltransferase complex subunit 3
FA2H fatty acid 2-hydroxylase
FAM53B family with sequence similarity 53, member B
FBXO46 F-box protein 46
FBXW12 F-box and WD repeat domain containing 12
FGFBP1 fibroblast growth factor binding protein 1
FKBP8 FK506 binding protein 8, 38kDa
FUZ fuzzy planar cell polarity protein
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPR1 G protein-coupled receptor 1
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HLX H2.0-like homeobox
HPS6 Hermansky-Pudlak syndrome 6
IFITM1 interferon induced transmembrane protein 1
IL24 interleukin 24
KIAA0513 KIAA0513
KIF20A kinesin family member 20A
KIFC3 kinesin family member C3
LIG4 ligase IV, DNA, ATP-dependent
MAGEA3 melanoma antigen family A3
MAGEF1 melanoma antigen family F1
MAP9 microtubule-associated protein 9
MBD5 methyl-CpG binding domain protein 5
MCMBP minichromosome maintenance complex binding protein
METTL1 methyltransferase like 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
NCS1 neuronal calcium sensor 1
NID2 nidogen 2 (osteonidogen)
NNMT nicotinamide N-methyltransferase
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
ODF2 outer dense fiber of sperm tails 2
OVGP1 oviductal glycoprotein 1, 120kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PDGFRL platelet-derived growth factor receptor-like
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLH polymerase (DNA directed), eta
POMT1 protein-O-mannosyltransferase 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RNF121 ring finger protein 121
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGR retinitis pigmentosa GTPase regulator
SAMD9 sterile alpha motif domain containing 9
SCML2 sex comb on midleg-like 2 (Drosophila)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPATA2L spermatogenesis associated 2-like
STAG3 stromal antigen 3
SYT17 synaptotagmin XVII
SYTL2 synaptotagmin-like 2
TAGLN3 transgelin 3
TGFB3 transforming growth factor, beta 3
TMEM184C transmembrane protein 184C
TMEM40 transmembrane protein 40
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TSC22D4 TSC22 domain family, member 4
TUBA3D tubulin, alpha 3d
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBTD1 ubiquitin domain containing 1
UNC119 unc-119 homolog (C. elegans)
USP19 ubiquitin specific peptidase 19
ZNF215 zinc finger protein 215
ZNF385D zinc finger protein 385D
ZNF592 zinc finger protein 592
ZNF747 zinc finger protein 747