nifedipine-1856 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nifedipine-1856 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACTN1 actinin, alpha 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AMT aminomethyltransferase
APOE apolipoprotein E
ATG3 autophagy related 3
ATP13A2 ATPase type 13A2
ATP9B ATPase, class II, type 9B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BPI bactericidal/permeability-increasing protein
BSDC1 BSD domain containing 1
CC2D1A coiled-coil and C2 domain containing 1A
CCDC57 coiled-coil domain containing 57
CDYL chromodomain protein, Y-like
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHD4 chromodomain helicase DNA binding protein 4
CIDEC cell death-inducing DFFA-like effector c
COPS7B COP9 signalosome subunit 7B
COX4I1 cytochrome c oxidase subunit IV isoform 1
CRABP2 cellular retinoic acid binding protein 2
CRYL1 crystallin, lambda 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DEAF1 DEAF1 transcription factor
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFCAB11 EF-hand calcium binding domain 11
EFCAB2 EF-hand calcium binding domain 2
ELAC1 elaC ribonuclease Z 1
EML3 echinoderm microtubule associated protein like 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM50B family with sequence similarity 50, member B
FBXO41 F-box protein 41
FN1 fibronectin 1
FRS3 fibroblast growth factor receptor substrate 3
GAREM GRB2 associated, regulator of MAPK1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
HDAC7 histone deacetylase 7
HEMK1 HemK methyltransferase family member 1
HMGN5 high mobility group nucleosome binding domain 5
HSPA4 heat shock 70kDa protein 4
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IL4 interleukin 4
ING4 inhibitor of growth family, member 4
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0894 KIAA0894 protein
KRIT1 KRIT1, ankyrin repeat containing
LAMP1 lysosomal-associated membrane protein 1
MAGED2 melanoma antigen family D2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K7CL MAP3K7 C-terminal like
METTL5 methyltransferase like 5
MIS18BP1 MIS18 binding protein 1
MST1 macrophage stimulating 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
NDE1 nudE neurodevelopment protein 1
NFX1 nuclear transcription factor, X-box binding 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR6A1 nuclear receptor subfamily 6, group A, member 1
OSBPL2 oxysterol binding protein-like 2
OXLD1 oxidoreductase-like domain containing 1
PACS2 phosphofurin acidic cluster sorting protein 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHGB5 protocadherin gamma subfamily B, 5
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PECR peroxisomal trans-2-enoyl-CoA reductase
PHF20 PHD finger protein 20
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRMT2IP PRMT2 interacting protein
PSG4 pregnancy specific beta-1-glycoprotein 4
RGS19 regulator of G-protein signaling 19
RPL10 ribosomal protein L10
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
S100A11 S100 calcium binding protein A11
SBNO2 strawberry notch homolog 2 (Drosophila)
SH3BP2 SH3-domain binding protein 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC25A44 solute carrier family 25, member 44
SRR serine racemase
SUGP1 SURP and G patch domain containing 1
TBC1D13 TBC1 domain family, member 13
TCP11L1 t-complex 11, testis-specific-like 1
TRA T cell receptor alpha locus
TRIM5 tripartite motif containing 5
TSC22D2 TSC22 domain family, member 2
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
TTC38 tetratricopeptide repeat domain 38
VARS valyl-tRNA synthetase
WDTC1 WD and tetratricopeptide repeats 1
ZNF324 zinc finger protein 324
ZNF74 zinc finger protein 74
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ACYP2 acylphosphatase 2, muscle type
AGO4 argonaute RISC catalytic component 4
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMCX5 armadillo repeat containing, X-linked 5
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BPGM 2,3-bisphosphoglycerate mutase
C17ORF70 chromosome 17 open reading frame 70
C21ORF91 chromosome 21 open reading frame 91
C3 complement component 3
C4ORF29 chromosome 4 open reading frame 29
C5AR1 complement component 5a receptor 1
CCNJ cyclin J
CD101 CD101 molecule
CD1D CD1d molecule
CDIP1 cell death-inducing p53 target 1
CENPB centromere protein B, 80kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP6 charged multivesicular body protein 6
CORO7 coronin 7
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DENND1A DENN/MADD domain containing 1A
DHRS9 dehydrogenase/reductase (SDR family) member 9
DKK2 dickkopf WNT signaling pathway inhibitor 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ECI2 enoyl-CoA delta isomerase 2
ENAH enabled homolog (Drosophila)
EPS8 epidermal growth factor receptor pathway substrate 8
FAM127A family with sequence similarity 127, member A
FAN1 FANCD2/FANCI-associated nuclease 1
GIPC1 GIPC PDZ domain containing family, member 1
GLTP glycolipid transfer protein
GNL1 guanine nucleotide binding protein-like 1
GPATCH2 G patch domain containing 2
GPHN gephyrin
GPR63 G protein-coupled receptor 63
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HILPDA hypoxia inducible lipid droplet-associated
HOMER1 homer scaffolding protein 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
KAT2A K(lysine) acetyltransferase 2A
KCNK5 potassium channel, two pore domain subfamily K, member 5
LYPLA2P1 lysophospholipase II pseudogene 1
MAPK12 mitogen-activated protein kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MECR mitochondrial trans-2-enoyl-CoA reductase
MED9 mediator complex subunit 9
MICALL2 MICAL-like 2
MOCS2 molybdenum cofactor synthesis 2
NABP2 nucleic acid binding protein 2
NAT6 N-acetyltransferase 6 (GCN5-related)
OCEL1 occludin/ELL domain containing 1
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDGFD platelet derived growth factor D
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G12A phospholipase A2, group XIIA
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLTP phospholipid transfer protein
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKX protein kinase, X-linked
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOB ras homolog family member B
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SMYD3 SET and MYND domain containing 3
SOAT1 sterol O-acyltransferase 1
SPAG1 sperm associated antigen 1
SPAG7 sperm associated antigen 7
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STX17 syntaxin 17
STXBP1 syntaxin binding protein 1
SURF2 surfeit 2
TBC1D31 TBC1 domain family, member 31
TESK1 testis-specific kinase 1
TMEM115 transmembrane protein 115
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TSC22D1 TSC22 domain family, member 1
TTBK2 tau tubulin kinase 2
ZBED8 zinc finger, BED-type containing 8
ZBTB10 zinc finger and BTB domain containing 10
ZBTB44 zinc finger and BTB domain containing 44
ZFP36 ZFP36 ring finger protein
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF197 zinc finger protein 197
ZNF215 zinc finger protein 215
ZNF232 zinc finger protein 232
ZNF675 zinc finger protein 675
ZNF787 zinc finger protein 787