| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the nifedipine-335 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AGRN | agrin |
| AIM1L | absent in melanoma 1-like |
| ANK1 | ankyrin 1, erythrocytic |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATXN2L | ataxin 2-like |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| CALY | calcyon neuron-specific vesicular protein |
| CAV3 | caveolin 3 |
| CD19 | CD19 molecule |
| CD2 | CD2 molecule |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CIDEA | cell death-inducing DFFA-like effector a |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| EFNB3 | ephrin-B3 |
| ELMO3 | engulfment and cell motility 3 |
| EMID1 | EMI domain containing 1 |
| EPHB1 | EPH receptor B1 |
| EXOC6B | exocyst complex component 6B |
| FAM110D | family with sequence similarity 110, member D |
| FAM188A | family with sequence similarity 188, member A |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FTCD | formimidoyltransferase cyclodeaminase |
| FYB | FYN binding protein |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIST1H3J | histone cluster 1, H3j |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXB7 | homeobox B7 |
| IL11 | interleukin 11 |
| IL5RA | interleukin 5 receptor, alpha |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA1467 | KIAA1467 |
| KIAA1614 | KIAA1614 |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIN7A | lin-7 homolog A (C. elegans) |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LUZP1 | leucine zipper protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MINK1 | misshapen-like kinase 1 |
| MMP8 | matrix metallopeptidase 8 |
| MTMR8 | myotubularin related protein 8 |
| MZF1 | myeloid zinc finger 1 |
| NOTCH3 | notch 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OGFR | opioid growth factor receptor |
| OR2F2 | olfactory receptor, family 2, subfamily F, member 2 |
| ORC4 | origin recognition complex, subunit 4 |
| OVOL1 | ovo-like zinc finger 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHF20 | PHD finger protein 20 |
| POLG | polymerase (DNA directed), gamma |
| PRDM14 | PR domain containing 14 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| REN | renin |
| RFPL2 | ret finger protein-like 2 |
| RGR | retinal G protein coupled receptor |
| SCLY | selenocysteine lyase |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIX6 | SIX homeobox 6 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SPEG | SPEG complex locus |
| SRPK2 | SRSF protein kinase 2 |
| STAG3 | stromal antigen 3 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYNGR1 | synaptogyrin 1 |
| TBL1X | transducin (beta)-like 1X-linked |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TMF1 | TATA element modulatory factor 1 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VCAM1 | vascular cell adhesion molecule 1 |
| ZNF117 | zinc finger protein 117 |
| ZNF3 | zinc finger protein 3 |
| ZNF460 | zinc finger protein 460 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| AHR | aryl hydrocarbon receptor |
| ALPK1 | alpha-kinase 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ASIP | agouti signaling protein |
| AXIN1 | axin 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CDH22 | cadherin 22, type 2 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN14 | claudin 14 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CRHBP | corticotropin releasing hormone binding protein |
| CRTAC1 | cartilage acidic protein 1 |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPX | eosinophil peroxidase |
| ERO1L | ERO1-like (S. cerevisiae) |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOLR2 | folate receptor 2 (fetal) |
| FOSL1 | FOS-like antigen 1 |
| FOXN2 | forkhead box N2 |
| GALK1 | galactokinase 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPR21 | G protein-coupled receptor 21 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HDAC11 | histone deacetylase 11 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HMX1 | H6 family homeobox 1 |
| IRX4 | iroquois homeobox 4 |
| JOSD1 | Josephin domain containing 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLF2 | Kruppel-like factor 2 |
| L1TD1 | LINE-1 type transposase domain containing 1 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LEFTY2 | left-right determination factor 2 |
| LHX6 | LIM homeobox 6 |
| LOC100127972 | uncharacterized LOC100127972 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MCOLN1 | mucolipin 1 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NLRP2 | NLR family, pyrin domain containing 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ONECUT2 | one cut homeobox 2 |
| PCDHB3 | protocadherin beta 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PNMT | phenylethanolamine N-methyltransferase |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PRSS50 | protease, serine, 50 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASIP1 | Ras interacting protein 1 |
| ROPN1B | rhophilin associated tail protein 1B |
| RORC | RAR-related orphan receptor C |
| RPAP2 | RNA polymerase II associated protein 2 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SATB1 | SATB homeobox 1 |
| SCAI | suppressor of cancer cell invasion |
| SETBP1 | SET binding protein 1 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SOX17 | SRY (sex determining region Y)-box 17 |
| SPRR2B | small proline-rich protein 2B |
| T | T, brachyury homolog (mouse) |
| TGM5 | transglutaminase 5 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TUBA4B | tubulin, alpha 4b |
| TUBB1 | tubulin, beta 1 class VI |
| UBXN2B | UBX domain protein 2B |
| USP18 | ubiquitin specific peptidase 18 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR18 | WD repeat domain 18 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| XYLT1 | xylosyltransferase I |
| XYLT2 | xylosyltransferase II |
| ZNF652 | zinc finger protein 652 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |