nifedipine-603 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the nifedipine-603 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADCY9 adenylate cyclase 9
AGFG2 ArfGAP with FG repeats 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ASIC1 acid sensing (proton gated) ion channel 1
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP1 bone morphogenetic protein 1
BRD1 bromodomain containing 1
BSDC1 BSD domain containing 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C9ORF156 chromosome 9 open reading frame 156
CA1 carbonic anhydrase I
CALCRL calcitonin receptor-like
CCDC87 coiled-coil domain containing 87
CCKAR cholecystokinin A receptor
CFAP70 cilia and flagella associated protein 70
CNTFR ciliary neurotrophic factor receptor
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DDIT3 DNA-damage-inducible transcript 3
DLG3 discs, large homolog 3 (Drosophila)
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK4 docking protein 4
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EPHB2 EPH receptor B2
ERCC4 excision repair cross-complementation group 4
FBLN1 fibulin 1
FGFR2 fibroblast growth factor receptor 2
FXR2 fragile X mental retardation, autosomal homolog 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLIPR1 GLI pathogenesis-related 1
HCG9 HLA complex group 9 (non-protein coding)
HIPK2 homeodomain interacting protein kinase 2
HIST1H4J histone cluster 1, H4j
IFI35 interferon-induced protein 35
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL10RA interleukin 10 receptor, alpha
KIF2A kinesin heavy chain member 2A
KLF15 Kruppel-like factor 15
KLHL28 kelch-like family member 28
LARP6 La ribonucleoprotein domain family, member 6
LINC00339 long intergenic non-protein coding RNA 339
LMF2 lipase maturation factor 2
LOC647070 uncharacterized LOC647070
MAGED2 melanoma antigen family D2
MAPK8 mitogen-activated protein kinase 8
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MNAT1 MNAT CDK-activating kinase assembly factor 1
MTUS1 microtubule associated tumor suppressor 1
NPFFR1 neuropeptide FF receptor 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PDE4C phosphodiesterase 4C, cAMP-specific
PEX19 peroxisomal biogenesis factor 19
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKNOX2 PBX/knotted 1 homeobox 2
POGLUT1 protein O-glucosyltransferase 1
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB11B RAB11B, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RNFT2 ring finger protein, transmembrane 2
RPS2 ribosomal protein S2
SETD4 SET domain containing 4
SH3BP2 SH3-domain binding protein 2
SIRPA signal-regulatory protein alpha
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLPI secretory leukocyte peptidase inhibitor
SON SON DNA binding protein
SPDEF SAM pointed domain containing ETS transcription factor
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SQSTM1 sequestosome 1
STMN1 stathmin 1
SUGP2 SURP and G patch domain containing 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMCC1 transmembrane and coiled-coil domain family 1
TMEM176A transmembrane protein 176A
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAK1 trafficking protein, kinesin binding 1
TTC3 tetratricopeptide repeat domain 3
TTLL4 tubulin tyrosine ligase-like family member 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WWTR1 WW domain containing transcription regulator 1
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZMYM6 zinc finger, MYM-type 6
ZNF264 zinc finger protein 264
ZNF576 zinc finger protein 576
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACOT8 acyl-CoA thioesterase 8
ACSL5 acyl-CoA synthetase long-chain family member 5
AGBL5 ATP/GTP binding protein-like 5
AHR aryl hydrocarbon receptor
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALLC allantoicase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
ATG2B autophagy related 2B
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BNC1 basonuclin 1
CA9 carbonic anhydrase IX
CCK cholecystokinin
CD8A CD8a molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CLCN2 chloride channel, voltage-sensitive 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COPZ2 coatomer protein complex, subunit zeta 2
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNASE1L2 deoxyribonuclease I-like 2
DOCK1 dedicator of cytokinesis 1
DPP6 dipeptidyl-peptidase 6
EDA2R ectodysplasin A2 receptor
EMILIN2 elastin microfibril interfacer 2
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM188A family with sequence similarity 188, member A
FAM76A family with sequence similarity 76, member A
FGGY FGGY carbohydrate kinase domain containing
FSCN3 fascin actin-bundling protein 3, testicular
GBP2 guanylate binding protein 2, interferon-inducible
GJC1 gap junction protein, gamma 1, 45kDa
HHLA1 HERV-H LTR-associating 1
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KDM7A lysine (K)-specific demethylase 7A
KIF20B kinesin family member 20B
KIFC3 kinesin family member C3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LECT1 leukocyte cell derived chemotaxin 1
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LIAS lipoic acid synthetase
LINC00574 long intergenic non-protein coding RNA 574
LRRC15 leucine rich repeat containing 15
MAGOHB mago-nashi homolog B (Drosophila)
MARC1 mitochondrial amidoxime reducing component 1
NELL2 NEL-like 2 (chicken)
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NRSN2 neurensin 2
NXPH3 neurexophilin 3
OLFML2B olfactomedin-like 2B
OSGIN1 oxidative stress induced growth inhibitor 1
PADI1 peptidyl arginine deiminase, type I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PF4 platelet factor 4
PFAS phosphoribosylformylglycinamidine synthase
PHF21A PHD finger protein 21A
PHOX2A paired-like homeobox 2a
PODNL1 podocan-like 1
PRSS16 protease, serine, 16 (thymus)
PRSS53 protease, serine, 53
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PZP pregnancy-zone protein
RAD54L RAD54-like (S. cerevisiae)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RCOR3 REST corepressor 3
RELN reelin
RSF1 remodeling and spacing factor 1
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS7 suppressor of cytokine signaling 7
SOD3 superoxide dismutase 3, extracellular
SPON2 spondin 2, extracellular matrix protein
TENM4 teneurin transmembrane protein 4
TEX15 testis expressed 15
TGM3 transglutaminase 3
TMEM127 transmembrane protein 127
TMEM8B transmembrane protein 8B
TOR4A torsin family 4, member A
TSHZ2 teashirt zinc finger homeobox 2
UBQLN4 ubiquilin 4
VIPR1 vasoactive intestinal peptide receptor 1
VSIG10 V-set and immunoglobulin domain containing 10
ZBTB22 zinc finger and BTB domain containing 22
ZNF770 zinc finger protein 770