nifenazone-1439 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the nifenazone-1439 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAM10 ADAM metallopeptidase domain 10
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BSDC1 BSD domain containing 1
C19ORF24 chromosome 19 open reading frame 24
C19ORF66 chromosome 19 open reading frame 66
CANT1 calcium activated nucleotidase 1
CC2D1A coiled-coil and C2 domain containing 1A
CCNJ cyclin J
CECR1 cat eye syndrome chromosome region, candidate 1
CLTA clathrin, light chain A
CNOT8 CCR4-NOT transcription complex, subunit 8
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRTC1 CREB regulated transcription coactivator 1
CUL4B cullin 4B
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCR2 chemokine (C-X-C motif) receptor 2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCAF8 DDB1 and CUL4 associated factor 8
DENND4A DENN/MADD domain containing 4A
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DUS2 dihydrouridine synthase 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELF2 E74-like factor 2 (ets domain transcription factor)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPX eosinophil peroxidase
FAM76A family with sequence similarity 76, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGL1 fibrinogen-like 1
GEMIN4 gem (nuclear organelle) associated protein 4
GLS glutaminase
GSTZ1 glutathione S-transferase zeta 1
H2AFV H2A histone family, member V
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HIST1H4J histone cluster 1, H4j
HP1BP3 heterochromatin protein 1, binding protein 3
IGHMBP2 immunoglobulin mu binding protein 2
IL18 interleukin 18
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCTD20 potassium channel tetramerization domain containing 20
KCTD3 potassium channel tetramerization domain containing 3
KLHL21 kelch-like family member 21
KRT86 keratin 86, type II
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LTB4R leukotriene B4 receptor
MAPK1 mitogen-activated protein kinase 1
MED18 mediator complex subunit 18
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MVK mevalonate kinase
MYO1C myosin IC
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NRP1 neuropilin 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDGFB platelet-derived growth factor beta polypeptide
PICALM phosphatidylinositol binding clathrin assembly protein
PIGR polymeric immunoglobulin receptor
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCD1 phospholipase C, delta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLSCR1 phospholipid scramblase 1
PSD4 pleckstrin and Sec7 domain containing 4
PTDSS2 phosphatidylserine synthase 2
PTK2 protein tyrosine kinase 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMYD5 SMYD family member 5
SRSF7 serine/arginine-rich splicing factor 7
SSH3 slingshot protein phosphatase 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAC SH3 and cysteine rich domain
TACC1 transforming, acidic coiled-coil containing protein 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR4 toll-like receptor 4
TSFM Ts translation elongation factor, mitochondrial
TSSC4 tumor suppressing subtransferable candidate 4
TTLL4 tubulin tyrosine ligase-like family member 4
UBA6 ubiquitin-like modifier activating enzyme 6
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE4B ubiquitination factor E4B
UBL3 ubiquitin-like 3
URI1 URI1, prefoldin-like chaperone
VAC14 Vac14 homolog (S. cerevisiae)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H12A zinc finger CCCH-type containing 12A
ZC4H2 zinc finger, C4H2 domain containing
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
ADM adrenomedullin
AMPD2 adenosine monophosphate deaminase 2
AMT aminomethyltransferase
APOC4 apolipoprotein C-IV
AQP2 aquaporin 2 (collecting duct)
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
BANP BTG3 associated nuclear protein
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C22ORF24 chromosome 22 open reading frame 24
C2ORF42 chromosome 2 open reading frame 42
CCNT1 cyclin T1
CDK6 cyclin-dependent kinase 6
CENPT centromere protein T
CETN1 centrin, EF-hand protein, 1
CFAP74 cilia and flagella associated protein 74
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNTD2 cyclin N-terminal domain containing 2
CRYM crystallin, mu
DBF4 DBF4 zinc finger
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEXI Dexi homolog (mouse)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DPH2 DPH2 homolog (S. cerevisiae)
DRD5 dopamine receptor D5
E4F1 E4F transcription factor 1
ECSIT ECSIT signalling integrator
EDAR ectodysplasin A receptor
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
FGF4 fibroblast growth factor 4
G6PD glucose-6-phosphate dehydrogenase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GLTSCR1 glioma tumor suppressor candidate region gene 1
GRM4 glutamate receptor, metabotropic 4
GRPR gastrin-releasing peptide receptor
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HIST1H2BF histone cluster 1, H2bf
HIST3H2A histone cluster 3, H2a
HLA-DMB major histocompatibility complex, class II, DM beta
HP haptoglobin
IGFLR1 IGF-like family receptor 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF13 Kruppel-like factor 13
KLF2 Kruppel-like factor 2
LCT lactase
LENEP lens epithelial protein
LY6E lymphocyte antigen 6 complex, locus E
MFSD12 major facilitator superfamily domain containing 12
MLPH melanophilin
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NOL6 nucleolar protein 6 (RNA-associated)
NPPA natriuretic peptide A
NSD1 nuclear receptor binding SET domain protein 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POLE polymerase (DNA directed), epsilon, catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPH peripherin
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RBBP5 retinoblastoma binding protein 5
RFPL3 ret finger protein-like 3
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF141 ring finger protein 141
SCN10A sodium channel, voltage gated, type X alpha subunit
SETD1B SET domain containing 1B
SKI SKI proto-oncogene
SNTA1 syntrophin, alpha 1
SRBD1 S1 RNA binding domain 1
SSNA1 Sjogren syndrome nuclear autoantigen 1
TERT telomerase reverse transcriptase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM134 transmembrane protein 134
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
VILL villin-like
WT1-AS WT1 antisense RNA
XAF1 XIAP associated factor 1
XDH xanthine dehydrogenase
ZBTB48 zinc finger and BTB domain containing 48
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2