| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the nifenazone-1439 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT11 | acyl-CoA thioesterase 11 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BSDC1 | BSD domain containing 1 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CANT1 | calcium activated nucleotidase 1 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCNJ | cyclin J |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLTA | clathrin, light chain A |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CUL4B | cullin 4B |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DCAF8 | DDB1 and CUL4 associated factor 8 |
| DENND4A | DENN/MADD domain containing 4A |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DUS2 | dihydrouridine synthase 2 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| EPX | eosinophil peroxidase |
| FAM76A | family with sequence similarity 76, member A |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FGL1 | fibrinogen-like 1 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GLS | glutaminase |
| GSTZ1 | glutathione S-transferase zeta 1 |
| H2AFV | H2A histone family, member V |
| HDAC7 | histone deacetylase 7 |
| HIRA | histone cell cycle regulator |
| HIST1H4J | histone cluster 1, H4j |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL18 | interleukin 18 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNC3 | potassium channel, voltage gated Shaw related subfamily C, member 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KLHL21 | kelch-like family member 21 |
| KRT86 | keratin 86, type II |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LTB4R | leukotriene B4 receptor |
| MAPK1 | mitogen-activated protein kinase 1 |
| MED18 | mediator complex subunit 18 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MVK | mevalonate kinase |
| MYO1C | myosin IC |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NRP1 | neuropilin 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIGR | polymeric immunoglobulin receptor |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| PLCD1 | phospholipase C, delta 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLSCR1 | phospholipid scramblase 1 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTK2 | protein tyrosine kinase 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMYD5 | SMYD family member 5 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSH3 | slingshot protein phosphatase 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STAC | SH3 and cysteine rich domain |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TLR4 | toll-like receptor 4 |
| TSFM | Ts translation elongation factor, mitochondrial |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| UBE4B | ubiquitination factor E4B |
| UBL3 | ubiquitin-like 3 |
| URI1 | URI1, prefoldin-like chaperone |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| VWA8 | von Willebrand factor A domain containing 8 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADM | adrenomedullin |
| AMPD2 | adenosine monophosphate deaminase 2 |
| AMT | aminomethyltransferase |
| APOC4 | apolipoprotein C-IV |
| AQP2 | aquaporin 2 (collecting duct) |
| AXIN1 | axin 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BANP | BTG3 associated nuclear protein |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C2ORF42 | chromosome 2 open reading frame 42 |
| CCNT1 | cyclin T1 |
| CDK6 | cyclin-dependent kinase 6 |
| CENPT | centromere protein T |
| CETN1 | centrin, EF-hand protein, 1 |
| CFAP74 | cilia and flagella associated protein 74 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CRYM | crystallin, mu |
| DBF4 | DBF4 zinc finger |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DEXI | Dexi homolog (mouse) |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DRD5 | dopamine receptor D5 |
| E4F1 | E4F transcription factor 1 |
| ECSIT | ECSIT signalling integrator |
| EDAR | ectodysplasin A receptor |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM50B | family with sequence similarity 50, member B |
| FANCF | Fanconi anemia, complementation group F |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FGF4 | fibroblast growth factor 4 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRPR | gastrin-releasing peptide receptor |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST3H2A | histone cluster 3, H2a |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HP | haptoglobin |
| IGFLR1 | IGF-like family receptor 1 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF13 | Kruppel-like factor 13 |
| KLF2 | Kruppel-like factor 2 |
| LCT | lactase |
| LENEP | lens epithelial protein |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MLPH | melanophilin |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPPA | natriuretic peptide A |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRPH | peripherin |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RBBP5 | retinoblastoma binding protein 5 |
| RFPL3 | ret finger protein-like 3 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF141 | ring finger protein 141 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SETD1B | SET domain containing 1B |
| SKI | SKI proto-oncogene |
| SNTA1 | syntrophin, alpha 1 |
| SRBD1 | S1 RNA binding domain 1 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| TERT | telomerase reverse transcriptase |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM134 | transmembrane protein 134 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| VILL | villin-like |
| WT1-AS | WT1 antisense RNA |
| XAF1 | XIAP associated factor 1 |
| XDH | xanthine dehydrogenase |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF778 | zinc finger protein 778 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |