nifenazone-2122 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nifenazone-2122 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADAP2 ArfGAP with dual PH domains 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALK anaplastic lymphoma receptor tyrosine kinase
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BEGAIN brain-enriched guanylate kinase-associated
BMP8B bone morphogenetic protein 8b
C10ORF10 chromosome 10 open reading frame 10
C16ORF59 chromosome 16 open reading frame 59
C1QL1 complement component 1, q subcomponent-like 1
CACYBP calcyclin binding protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNOT4 CCR4-NOT transcription complex, subunit 4
CPNE7 copine VII
CPT1A carnitine palmitoyltransferase 1A (liver)
CSHL1 chorionic somatomammotropin hormone-like 1
CST4 cystatin S
DBP D site of albumin promoter (albumin D-box) binding protein
ELOVL5 ELOVL fatty acid elongase 5
EN2 engrailed homeobox 2
EPS8L1 EPS8-like 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EXD3 exonuclease 3'-5' domain containing 3
EXOC6B exocyst complex component 6B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGFR1 fibroblast growth factor receptor 1
FLJ10038 uncharacterized protein FLJ10038
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L2 galactosidase, beta 1-like 2
GLS2 glutaminase 2 (liver, mitochondrial)
GRM7 glutamate receptor, metabotropic 7
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IHH indian hedgehog
JUND jun D proto-oncogene
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMNA lamin A/C
LRP1 low density lipoprotein receptor-related protein 1
LRRK1 leucine-rich repeat kinase 1
MAPK11 mitogen-activated protein kinase 11
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MIIP migration and invasion inhibitory protein
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOP14-AS1 NOP14 antisense RNA 1
NOTCH2 notch 2
OSBPL10 oxysterol binding protein-like 10
PCIF1 PDX1 C-terminal inhibiting factor 1
PDE10A phosphodiesterase 10A
PEX5 peroxisomal biogenesis factor 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKP3 plakophilin 3
PLD1 phospholipase D1, phosphatidylcholine-specific
PRKG2 protein kinase, cGMP-dependent, type II
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSD3 pleckstrin and Sec7 domain containing 3
PTCRA pre T-cell antigen receptor alpha
RAB28 RAB28, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RARA retinoic acid receptor, alpha
REC8 REC8 meiotic recombination protein
REST RE1-silencing transcription factor
RGS10 regulator of G-protein signaling 10
RNF122 ring finger protein 122
RUNX1 runt-related transcription factor 1
SCARB1 scavenger receptor class B, member 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SOX21 SRY (sex determining region Y)-box 21
SPATA5L1 spermatogenesis associated 5-like 1
SPATA6 spermatogenesis associated 6
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTB spectrin, beta, erythrocytic
SSTR5 somatostatin receptor 5
STS steroid sulfatase (microsomal), isozyme S
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TGFA transforming growth factor, alpha
TMEM231 transmembrane protein 231
TMEM246 transmembrane protein 246
TMEM259 transmembrane protein 259
TNS4 tensin 4
TRIM23 tripartite motif containing 23
TSPAN8 tetraspanin 8
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USF2 upstream transcription factor 2, c-fos interacting
USP48 ubiquitin specific peptidase 48
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
WIPF1 WAS/WASL interacting protein family, member 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AFAP1 actin filament associated protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCL2L2 BCL2-like 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC1 basonuclin 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C16ORF45 chromosome 16 open reading frame 45
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCS copper chaperone for superoxide dismutase
CD302 CD302 molecule
CENPJ centromere protein J
CGREF1 cell growth regulator with EF-hand domain 1
CLSPN claspin
CLUH clustered mitochondria (cluA/CLU1) homolog
CRELD2 cysteine-rich with EGF-like domains 2
DEAF1 DEAF1 transcription factor
DPY19L2P2 DPY19L2 pseudogene 2
EFCAB2 EF-hand calcium binding domain 2
ERAP2 endoplasmic reticulum aminopeptidase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155A family with sequence similarity 155, member A
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNS galactosamine (N-acetyl)-6-sulfatase
GATAD2A GATA zinc finger domain containing 2A
GBX2 gastrulation brain homeobox 2
GCC1 GRIP and coiled-coil domain containing 1
GSR glutathione reductase
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HSF2BP heat shock transcription factor 2 binding protein
HYAL3 hyaluronoglucosaminidase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLHL28 kelch-like family member 28
LAMA5 laminin, alpha 5
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
MAPK3 mitogen-activated protein kinase 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPS34 mitochondrial ribosomal protein S34
MTMR9 myotubularin related protein 9
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NABP2 nucleic acid binding protein 2
NBEAL2 neurobeachin-like 2
NDEL1 nudE neurodevelopment protein 1-like 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PLAC8 placenta-specific 8
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLXNB3 plexin B3
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RABL6 RAB, member RAS oncogene family-like 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM28 RNA binding motif protein 28
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF121 ring finger protein 121
RPUSD2 RNA pseudouridylate synthase domain containing 2
SERINC5 serine incorporator 5
SH3BGR SH3 domain binding glutamate-rich protein
SNHG20 small nucleolar RNA host gene 20
STARD13 StAR-related lipid transfer (START) domain containing 13
STK16 serine/threonine kinase 16
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYT17 synaptotagmin XVII
TH tyrosine hydroxylase
TMEM120B transmembrane protein 120B
TMEM183A transmembrane protein 183A
TMEM254 transmembrane protein 254
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAPPC2 trafficking protein particle complex 2
TRIM66 tripartite motif containing 66
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
WDR37 WD repeat domain 37
WRAP73 WD repeat containing, antisense to TP73
ZBTB3 zinc finger and BTB domain containing 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF137P zinc finger protein 137, pseudogene
ZNF324 zinc finger protein 324
ZNF408 zinc finger protein 408
ZNF671 zinc finger protein 671
ZNF767P zinc finger family member 767, pseudogene
ZNF787 zinc finger protein 787