| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the nifenazone-2285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AHNAK | AHNAK nucleoprotein |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATN1 | atrophin 1 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP1 | bone morphogenetic protein 1 |
| BMP2K | BMP2 inducible kinase |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARD9 | caspase recruitment domain family, member 9 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CFHR4 | complement factor H-related 4 |
| CRTAC1 | cartilage acidic protein 1 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| ETV7 | ets variant 7 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLRA3 | glycine receptor, alpha 3 |
| GPR162 | G protein-coupled receptor 162 |
| GPR182 | G protein-coupled receptor 182 |
| GPR75 | G protein-coupled receptor 75 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL1RN | interleukin 1 receptor antagonist |
| ITGB5 | integrin, beta 5 |
| JMJD6 | jumonji domain containing 6 |
| KIAA1456 | KIAA1456 |
| KIAA1462 | KIAA1462 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLK2 | kallikrein-related peptidase 2 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LAMC2 | laminin, gamma 2 |
| LMNA | lamin A/C |
| LYZ | lysozyme |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MED18 | mediator complex subunit 18 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MTSS1L | metastasis suppressor 1-like |
| NEK1 | NIMA-related kinase 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NRP2 | neuropilin 2 |
| OMG | oligodendrocyte myelin glycoprotein |
| PAX5 | paired box 5 |
| PCDH12 | protocadherin 12 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM4 | PDZ and LIM domain 4 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PGR | progesterone receptor |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLCE1 | phospholipase C, epsilon 1 |
| PLK3 | polo-like kinase 3 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RIN3 | Ras and Rab interactor 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RREB1 | ras responsive element binding protein 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SHOX2 | short stature homeobox 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC28A3 | solute carrier family 28 (concentrative nucleoside transporter), member 3 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SRGN | serglycin |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYT2 | synaptotagmin II |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM29 | tripartite motif containing 29 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| USP2 | ubiquitin specific peptidase 2 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VCAN | versican |
| YOD1 | YOD1 deubiquitinase |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BFSP1 | beaded filament structural protein 1, filensin |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BORA | bora, aurora kinase A activator |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C3 | complement component 3 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC25 | coiled-coil domain containing 25 |
| CD302 | CD302 molecule |
| CEP85 | centrosomal protein 85kDa |
| CES3 | carboxylesterase 3 |
| CLDN1 | claudin 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRY2 | cryptochrome circadian clock 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FADS2 | fatty acid desaturase 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPATCH2L | G patch domain containing 2-like |
| GPR21 | G protein-coupled receptor 21 |
| GRAMD3 | GRAM domain containing 3 |
| H1F0 | H1 histone family, member 0 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXA4 | homeobox A4 |
| HOXC8 | homeobox C8 |
| IPO8 | importin 8 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA0319L | KIAA0319-like |
| LIF | leukemia inhibitory factor |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCOLN1 | mucolipin 1 |
| MED24 | mediator complex subunit 24 |
| METTL16 | methyltransferase like 16 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MYO1E | myosin IE |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OTUD3 | OTU deubiquitinase 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PC | pyruvate carboxylase |
| PCDHA6 | protocadherin alpha 6 |
| PITX2 | paired-like homeodomain 2 |
| PLD3 | phospholipase D family, member 3 |
| PRDM16 | PR domain containing 16 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAI14 | retinoic acid induced 14 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RFPL1S | RFPL1 antisense RNA 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STIM1 | stromal interaction molecule 1 |
| STMN3 | stathmin-like 3 |
| STRN | striatin, calmodulin binding protein |
| SYNC | syncoilin, intermediate filament protein |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D2 | TBC1 domain family, member 2 |
| TBX19 | T-box 19 |
| TCTA | T-cell leukemia translocation altered |
| TOP3B | topoisomerase (DNA) III beta |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRABD | TraB domain containing |
| TRIM66 | tripartite motif containing 66 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF226 | zinc finger protein 226 |
| ZNF280D | zinc finger protein 280D |
| ZNF324 | zinc finger protein 324 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF510 | zinc finger protein 510 |
| ZNF552 | zinc finger protein 552 |
| ZW10 | zw10 kinetochore protein |