nifenazone-2285 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the nifenazone-2285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACTC1 actin, alpha, cardiac muscle 1
ADAM12 ADAM metallopeptidase domain 12
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AHNAK AHNAK nucleoprotein
AKAP6 A kinase (PRKA) anchor protein 6
ALOX15B arachidonate 15-lipoxygenase, type B
ANP32A-IT1 ANP32A intronic transcript 1
APLP1 amyloid beta (A4) precursor-like protein 1
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ARHGAP35 Rho GTPase activating protein 35
ARPIN actin-related protein 2/3 complex inhibitor
ATN1 atrophin 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BCL6 B-cell CLL/lymphoma 6
BMP1 bone morphogenetic protein 1
BMP2K BMP2 inducible kinase
C10ORF12 chromosome 10 open reading frame 12
C1ORF95 chromosome 1 open reading frame 95
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CARD9 caspase recruitment domain family, member 9
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFHR4 complement factor H-related 4
CRTAC1 cartilage acidic protein 1
CXCR6 chemokine (C-X-C motif) receptor 6
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
ETV7 ets variant 7
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GGT1 gamma-glutamyltransferase 1
GLRA3 glycine receptor, alpha 3
GPR162 G protein-coupled receptor 162
GPR182 G protein-coupled receptor 182
GPR75 G protein-coupled receptor 75
GZMK granzyme K (granzyme 3; tryptase II)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL1RN interleukin 1 receptor antagonist
ITGB5 integrin, beta 5
JMJD6 jumonji domain containing 6
KIAA1456 KIAA1456
KIAA1462 KIAA1462
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK2 kallikrein-related peptidase 2
KRT19P2 keratin 19 pseudogene 2
LAMC2 laminin, gamma 2
LMNA lamin A/C
LYZ lysozyme
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MED18 mediator complex subunit 18
MORC1 MORC family CW-type zinc finger 1
MTSS1L metastasis suppressor 1-like
NEK1 NIMA-related kinase 1
NEU3 sialidase 3 (membrane sialidase)
NRP2 neuropilin 2
OMG oligodendrocyte myelin glycoprotein
PAX5 paired box 5
PCDH12 protocadherin 12
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM4 PDZ and LIM domain 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGR progesterone receptor
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCE1 phospholipase C, epsilon 1
PLK3 polo-like kinase 3
PRB3 proline-rich protein BstNI subfamily 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSD3 pleckstrin and Sec7 domain containing 3
PTCRA pre T-cell antigen receptor alpha
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RGS14 regulator of G-protein signaling 14
RIN3 Ras and Rab interactor 3
RNF126P1 ring finger protein 126 pseudogene 1
RREB1 ras responsive element binding protein 1
SCD5 stearoyl-CoA desaturase 5
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEZ6L seizure related 6 homolog (mouse)-like
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHOX2 short stature homeobox 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SNED1 sushi, nidogen and EGF-like domains 1
SPON1 spondin 1, extracellular matrix protein
SRGN serglycin
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT2 synaptotagmin II
TCP11L1 t-complex 11, testis-specific-like 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM29 tripartite motif containing 29
TRPV6 transient receptor potential cation channel, subfamily V, member 6
USP2 ubiquitin specific peptidase 2
VAV2 vav 2 guanine nucleotide exchange factor
VCAN versican
YOD1 YOD1 deubiquitinase

decreased expression

Symbol Name
ALS2CL ALS2 C-terminal like
APOLD1 apolipoprotein L domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX2 armadillo repeat containing, X-linked 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAT1 alpha tubulin acetyltransferase 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BEGAIN brain-enriched guanylate kinase-associated
BFSP1 beaded filament structural protein 1, filensin
BGLAP bone gamma-carboxyglutamate (gla) protein
BORA bora, aurora kinase A activator
C14ORF93 chromosome 14 open reading frame 93
C3 complement component 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CCDC25 coiled-coil domain containing 25
CD302 CD302 molecule
CEP85 centrosomal protein 85kDa
CES3 carboxylesterase 3
CLDN1 claudin 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRY2 cryptochrome circadian clock 2
CUZD1 CUB and zona pellucida-like domains 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FADS2 fatty acid desaturase 2
FKBP10 FK506 binding protein 10, 65 kDa
GFI1 growth factor independent 1 transcription repressor
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPATCH2L G patch domain containing 2-like
GPR21 G protein-coupled receptor 21
GRAMD3 GRAM domain containing 3
H1F0 H1 histone family, member 0
HIST2H2AA3 histone cluster 2, H2aa3
HMGB3P1 high mobility group box 3 pseudogene 1
HOXA4 homeobox A4
HOXC8 homeobox C8
IPO8 importin 8
KAT2A K(lysine) acetyltransferase 2A
KIAA0319L KIAA0319-like
LIF leukemia inhibitory factor
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC8E leucine rich repeat containing 8 family, member E
MBNL3 muscleblind-like splicing regulator 3
MCOLN1 mucolipin 1
MED24 mediator complex subunit 24
METTL16 methyltransferase like 16
MPDU1 mannose-P-dolichol utilization defect 1
MYO1E myosin IE
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUD3 OTU deubiquitinase 3
PAIP2B poly(A) binding protein interacting protein 2B
PC pyruvate carboxylase
PCDHA6 protocadherin alpha 6
PITX2 paired-like homeodomain 2
PLD3 phospholipase D family, member 3
PRDM16 PR domain containing 16
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAI14 retinoic acid induced 14
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFPL1S RFPL1 antisense RNA 1
SAYSD1 SAYSVFN motif domain containing 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SPINK4 serine peptidase inhibitor, Kazal type 4
STIM1 stromal interaction molecule 1
STMN3 stathmin-like 3
STRN striatin, calmodulin binding protein
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D2 TBC1 domain family, member 2
TBX19 T-box 19
TCTA T-cell leukemia translocation altered
TOP3B topoisomerase (DNA) III beta
TPST1 tyrosylprotein sulfotransferase 1
TRABD TraB domain containing
TRIM66 tripartite motif containing 66
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF226 zinc finger protein 226
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF510 zinc finger protein 510
ZNF552 zinc finger protein 552
ZW10 zw10 kinetochore protein