nifenazone-7314 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nifenazone-7314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ABHD2 abhydrolase domain containing 2
ACACA acetyl-CoA carboxylase alpha
ADAM17 ADAM metallopeptidase domain 17
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATXN2L ataxin 2-like
BAIAP3 BAI1-associated protein 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTN3A1 butyrophilin, subfamily 3, member A1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C7 complement component 7
C9ORF156 chromosome 9 open reading frame 156
C9ORF9 chromosome 9 open reading frame 9
CAMKV CaM kinase-like vesicle-associated
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNT2 cyclin T2
CCSER2 coiled-coil serine-rich protein 2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK3 cyclin-dependent kinase 3
COL3A1 collagen, type III, alpha 1
COL7A1 collagen, type VII, alpha 1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DLK1 delta-like 1 homolog (Drosophila)
EDA ectodysplasin A
FAM184A family with sequence similarity 184, member A
FSTL3 follistatin-like 3 (secreted glycoprotein)
GREM1 gremlin 1, DAN family BMP antagonist
GSTA1 glutathione S-transferase alpha 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA11 homeobox A11
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IFI44L interferon-induced protein 44-like
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM7A lysine (K)-specific demethylase 7A
KLHL20 kelch-like family member 20
LIMK1 LIM domain kinase 1
LINS lines homolog (Drosophila)
MAP7 microtubule-associated protein 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MATN3 matrilin 3
MED22 mediator complex subunit 22
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MXD4 MAX dimerization protein 4
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYL10 myosin, light chain 10, regulatory
NDP Norrie disease (pseudoglioma)
NF1 neurofibromin 1
NFIB nuclear factor I/B
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NID2 nidogen 2 (osteonidogen)
NUP50 nucleoporin 50kDa
PAQR6 progestin and adipoQ receptor family member VI
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB31 RAB31, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAD51B RAD51 paralog B
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS10 regulator of G-protein signaling 10
RGS4 regulator of G-protein signaling 4
RXRA retinoid X receptor, alpha
S100A13 S100 calcium binding protein A13
SCARB1 scavenger receptor class B, member 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SENP6 SUMO1/sentrin specific peptidase 6
SEPP1 selenoprotein P, plasma, 1
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD8 SET domain containing (lysine methyltransferase) 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOD3 superoxide dismutase 3, extracellular
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRPX2 sushi-repeat containing protein, X-linked 2
STAC SH3 and cysteine rich domain
STAR steroidogenic acute regulatory protein
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TBC1D22A TBC1 domain family, member 22A
TCF12 transcription factor 12
THOC5 THO complex 5
TMC5 transmembrane channel-like 5
TP53I11 tumor protein p53 inducible protein 11
TRAF2 TNF receptor-associated factor 2
TSC22D3 TSC22 domain family, member 3
UNC119 unc-119 homolog (C. elegans)
VAV2 vav 2 guanine nucleotide exchange factor
ZFP64 ZFP64 zinc finger protein
ZNF589 zinc finger protein 589
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAG4 BCL2-associated athanogene 4
BIRC3 baculoviral IAP repeat containing 3
BTF3P12 basic transcription factor 3 pseudogene 12
C9ORF40 chromosome 9 open reading frame 40
CAPN15 calpain 15
CCP110 centriolar coiled coil protein 110kDa
CDC37L1 cell division cycle 37-like 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNGB3 cyclic nucleotide gated channel beta 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPPED1 calcineurin-like phosphoesterase domain containing 1
CST4 cystatin S
DBR1 debranching RNA lariats 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
EDC4 enhancer of mRNA decapping 4
EFNA3 ephrin-A3
EGF epidermal growth factor
F3 coagulation factor III (thromboplastin, tissue factor)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF2 fibroblast growth factor 2 (basic)
FOXC1 forkhead box C1
GPATCH2L G patch domain containing 2-like
GPR176 G protein-coupled receptor 176
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTPBP6 GTP binding protein 6 (putative)
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIRA histone cell cycle regulator
HIRIP3 HIRA interacting protein 3
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HOXC8 homeobox C8
IFT54 intraflagellar transport 54
JUNB jun B proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM5C lysine (K)-specific demethylase 5C
LINC00339 long intergenic non-protein coding RNA 339
LITAF lipopolysaccharide-induced TNF factor
LMCD1 LIM and cysteine-rich domains 1
LRRC6 leucine rich repeat containing 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
METTL16 methyltransferase like 16
MMD monocyte to macrophage differentiation-associated
MMP13 matrix metallopeptidase 13
MUM1 melanoma associated antigen (mutated) 1
MYL5 myosin, light chain 5, regulatory
NAG18 NAG18 mRNA
NBEAL2 neurobeachin-like 2
NDRG4 NDRG family member 4
NOL12 nucleolar protein 12
NTHL1 nth endonuclease III-like 1 (E. coli)
ODF2 outer dense fiber of sperm tails 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD3 OTU deubiquitinase 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCBP4 poly(rC) binding protein 4
PLD2 phospholipase D2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PTPRE protein tyrosine phosphatase, receptor type, E
QTRT1 queuine tRNA-ribosyltransferase 1
RGS17 regulator of G-protein signaling 17
RHOBTB2 Rho-related BTB domain containing 2
RWDD2A RWD domain containing 2A
S100A3 S100 calcium binding protein A3
SCD5 stearoyl-CoA desaturase 5
SDF2 stromal cell-derived factor 2
SIX1 SIX homeobox 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SRBD1 S1 RNA binding domain 1
STX17 syntaxin 17
TCTN1 tectonic family member 1
TENM1 teneurin transmembrane protein 1
TMEM242 transmembrane protein 242
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPMT thiopurine S-methyltransferase
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
USP32 ubiquitin specific peptidase 32
VEGFB vascular endothelial growth factor B
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF165 zinc finger protein 165
ZNF197 zinc finger protein 197
ZNF426 zinc finger protein 426
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2
ZNRD1-AS1 ZNRD1 antisense RNA 1