niflumic acid-2399 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the niflumic acid-2399 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGRN agrin
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ASIC4 acid sensing (proton gated) ion channel family member 4
AVPR1B arginine vasopressin receptor 1B
CACFD1 calcium channel flower domain containing 1
CALB1 calbindin 1, 28kDa
CALD1 caldesmon 1
CARD14 caspase recruitment domain family, member 14
CCDC69 coiled-coil domain containing 69
CD300C CD300c molecule
CD58 CD58 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
COL9A2 collagen, type IX, alpha 2
CXCL13 chemokine (C-X-C motif) ligand 13
CYB561 cytochrome b561
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DOCK6 dedicator of cytokinesis 6
EDA ectodysplasin A
F12 coagulation factor XII (Hageman factor)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FRZB frizzled-related protein
GAREM GRB2 associated, regulator of MAPK1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCRT hypocretin (orexin) neuropeptide precursor
HOXA1 homeobox A1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL27RA interleukin 27 receptor, alpha
INE1 inactivation escape 1 (non-protein coding)
IQSEC1 IQ motif and Sec7 domain 1
KALRN kalirin, RhoGEF kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA0895 KIAA0895
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL22 kelch-like family member 22
KRT19P2 keratin 19 pseudogene 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC8B leucine rich repeat containing 8 family, member B
MAPK7 mitogen-activated protein kinase 7
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP25 matrix metallopeptidase 25
MVD mevalonate (diphospho) decarboxylase
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OAZ3 ornithine decarboxylase antizyme 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM5 PDZ and LIM domain 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PMFBP1 polyamine modulated factor 1 binding protein 1
PML promyelocytic leukemia
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKCA protein kinase C, alpha
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTAFR platelet-activating factor receptor
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB13 RAB13, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54B RAD54 homolog B (S. cerevisiae)
RBPMS RNA binding protein with multiple splicing
RGS3 regulator of G-protein signaling 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIMS3 regulating synaptic membrane exocytosis 3
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SAFB scaffold attachment factor B
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SOCS3 suppressor of cytokine signaling 3
SP4 Sp4 transcription factor
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRPK2 SRSF protein kinase 2
SS18 synovial sarcoma translocation, chromosome 18
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAPBP TAP binding protein (tapasin)
TCP10 t-complex 10
TROVE2 TROVE domain family, member 2
TRPS1 trichorhinophalangeal syndrome I
UBXN1 UBX domain protein 1
UGCG UDP-glucose ceramide glucosyltransferase
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AHDC1 AT hook, DNA binding motif, containing 1
ANO10 anoctamin 10
AOAH acyloxyacyl hydrolase (neutrophil)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
BAMBI BMP and activin membrane-bound inhibitor
BBC3 BCL2 binding component 3
BHLHE41 basic helix-loop-helix family, member e41
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
CAPN5 calpain 5
CCDC85C coiled-coil domain containing 85C
CCL2 chemokine (C-C motif) ligand 2
CDA cytidine deaminase
CDK6 cyclin-dependent kinase 6
CST3 cystatin C
CXCL2 chemokine (C-X-C motif) ligand 2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDN dendrin
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM50B family with sequence similarity 50, member B
FAM57A family with sequence similarity 57, member A
FGL1 fibrinogen-like 1
FLCN folliculin
FURIN furin (paired basic amino acid cleaving enzyme)
GALK1 galactokinase 1
GRPR gastrin-releasing peptide receptor
GSTZ1 glutathione S-transferase zeta 1
HIST1H2BE histone cluster 1, H2be
INF2 inverted formin, FH2 and WH2 domain containing
IRF7 interferon regulatory factor 7
KIF20A kinesin family member 20A
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LMBR1L limb development membrane protein 1-like
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRP5 low density lipoprotein receptor-related protein 5
LTBP2 latent transforming growth factor beta binding protein 2
MAGEF1 melanoma antigen family F1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MED9 mediator complex subunit 9
METTL16 methyltransferase like 16
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MICA MHC class I polypeptide-related sequence A
MOCOS molybdenum cofactor sulfurase
MPDU1 mannose-P-dolichol utilization defect 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
PARG poly (ADP-ribose) glycohydrolase
PDZD7 PDZ domain containing 7
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PODXL2 podocalyxin-like 2
POLM polymerase (DNA directed), mu
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POM121 POM121 transmembrane nucleoporin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB33B RAB33B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S1PR4 sphingosine-1-phosphate receptor 4
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SETD1A SET domain containing 1A
SLC22A14 solute carrier family 22, member 14
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMA4 glucuronidase, beta pseudogene
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STXBP1 syntaxin binding protein 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNJ2BP synaptojanin 2 binding protein
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TESK2 testis-specific kinase 2
TMEM110 transmembrane protein 110
TMEM159 transmembrane protein 159
TMOD3 tropomodulin 3 (ubiquitous)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP19 ubiquitin specific peptidase 19
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR13 WD repeat domain 13
ZNF134 zinc finger protein 134
ZNF253 zinc finger protein 253
ZNF276 zinc finger protein 276
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493
ZNF696 zinc finger protein 696
ZNF747 zinc finger protein 747