niflumic acid-5490 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the niflumic acid-5490 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AKAP9 A kinase (PRKA) anchor protein 9
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
APOM apolipoprotein M
BLVRA biliverdin reductase A
BST2 bone marrow stromal cell antigen 2
BTG3 BTG family, member 3
C19ORF66 chromosome 19 open reading frame 66
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACTIN cactin, spliceosome C complex subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC93 coiled-coil domain containing 93
CCNO cyclin O
CNR1 cannabinoid receptor 1 (brain)
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CPA4 carboxypeptidase A4
CSF1R colony stimulating factor 1 receptor
DCN decorin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELMO2 engulfment and cell motility 2
EPHB2 EPH receptor B2
FAM149B1 family with sequence similarity 149, member B1
FAM214B family with sequence similarity 214, member B
FDPS farnesyl diphosphate synthase
GAB1 GRB2-associated binding protein 1
GIMAP5 GTPase, IMAP family member 5
GPR176 G protein-coupled receptor 176
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AI histone cluster 1, H2ai
HNMT histamine N-methyltransferase
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
ING2 inhibitor of growth family, member 2
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITM2A integral membrane protein 2A
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL24 kelch-like family member 24
KRT38 keratin 38, type I
LAMP3 lysosomal-associated membrane protein 3
LMF1 lipase maturation factor 1
LOC100131532 uncharacterized LOC100131532
LRP6 low density lipoprotein receptor-related protein 6
MFN2 mitofusin 2
MRPS18C mitochondrial ribosomal protein S18C
MX2 MX dynamin-like GTPase 2
MYOF myoferlin
MZF1 myeloid zinc finger 1
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP3 NEDD4 binding protein 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PARP12 poly (ADP-ribose) polymerase family, member 12
PAX2 paired box 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLSCR1 phospholipid scramblase 1
PLXDC1 plexin domain containing 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTRF polymerase I and transcript release factor
RAD51 RAD51 recombinase
SAMD4A sterile alpha motif domain containing 4A
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMTN smoothelin
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SP100 SP100 nuclear antigen
SP110 SP110 nuclear body protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STK11 serine/threonine kinase 11
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBCD tubulin folding cofactor D
TSFM Ts translation elongation factor, mitochondrial
TSPAN32 tetraspanin 32
TYRP1 tyrosinase-related protein 1
UNC119 unc-119 homolog (C. elegans)
UPK2 uroplakin 2
UTS2 urotensin 2
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZNF407 zinc finger protein 407
ZNF532 zinc finger protein 532

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADTRP androgen-dependent TFPI-regulating protein
ASB7 ankyrin repeat and SOCS box containing 7
BAG4 BCL2-associated athanogene 4
BBS7 Bardet-Biedl syndrome 7
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF29 chromosome 4 open reading frame 29
C5 complement component 5
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCNL2 cyclin L2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD83 CD83 molecule
CENPO centromere protein O
CLDN15 claudin 15
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGKE diacylglycerol kinase, epsilon 64kDa
DSCAM Down syndrome cell adhesion molecule
ENO2 enolase 2 (gamma, neuronal)
F2R coagulation factor II (thrombin) receptor
FADS3 fatty acid desaturase 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FURIN furin (paired basic amino acid cleaving enzyme)
GALT galactose-1-phosphate uridylyltransferase
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
INO80D INO80 complex subunit D
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF6 interferon regulatory factor 6
JMJD4 jumonji domain containing 4
LAMA3 laminin, alpha 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMCD1 LIM and cysteine-rich domains 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAMLD1 mastermind-like domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED9 mediator complex subunit 9
MYO1F myosin IF
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPY5R neuropeptide Y receptor Y5
ODF2 outer dense fiber of sperm tails 2
ONECUT2 one cut homeobox 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PEX26 peroxisomal biogenesis factor 26
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PODXL2 podocalyxin-like 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PRSS16 protease, serine, 16 (thymus)
PRSS22 protease, serine, 22
PTCD2 pentatricopeptide repeat domain 2
QPCT glutaminyl-peptide cyclotransferase
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCAF4 SR-related CTD-associated factor 4
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKI SKI proto-oncogene
SLC10A3 solute carrier family 10, member 3
SLC25A40 solute carrier family 25, member 40
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SPINK4 serine peptidase inhibitor, Kazal type 4
SRPX sushi-repeat containing protein, X-linked
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TESC tescalcin
TM6SF1 transmembrane 6 superfamily member 1
TMEM183A transmembrane protein 183A
TPST2 tyrosylprotein sulfotransferase 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VAX2 ventral anterior homeobox 2
XAB2 XPA binding protein 2
ZNF276 zinc finger protein 276
ZNF639 zinc finger protein 639
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26