| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nifuroxazide-2490 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA2C | adrenoceptor alpha 2C |
| AFF2 | AF4/FMR2 family, member 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANXA2P2 | annexin A2 pseudogene 2 |
| AQP1 | aquaporin 1 (Colton blood group) |
| BCL2L1 | BCL2-like 1 |
| CABP1 | calcium binding protein 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CARD10 | caspase recruitment domain family, member 10 |
| CBX8 | chromobox homolog 8 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDO1 | cysteine dioxygenase type 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLEC4E | C-type lectin domain family 4, member E |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CREM | cAMP responsive element modulator |
| DCT | dopachrome tautomerase |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DUSP7 | dual specificity phosphatase 7 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EGR4 | early growth response 4 |
| EML2 | echinoderm microtubule associated protein like 2 |
| FBXO4 | F-box protein 4 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| GAS8 | growth arrest-specific 8 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GP6 | glycoprotein VI (platelet) |
| GPR22 | G protein-coupled receptor 22 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BN | histone cluster 1, H2bn |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HMOX1 | heme oxygenase 1 |
| HNMT | histamine N-methyltransferase |
| HOXA4 | homeobox A4 |
| HOXC4 | homeobox C4 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IL1RAP | interleukin 1 receptor accessory protein |
| INO80B | INO80 complex subunit B |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LIMK1 | LIM domain kinase 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAPT | microtubule-associated protein tau |
| MDFI | MyoD family inhibitor |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPPA | natriuretic peptide A |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OPTN | optineurin |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 |
| RANBP1 | RAN binding protein 1 |
| RBP4 | retinol binding protein 4, plasma |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPATA1 | spermatogenesis associated 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSH3 | slingshot protein phosphatase 3 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| SYT5 | synaptotagmin V |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| UPK3B | uroplakin 3B |
| USP29 | ubiquitin specific peptidase 29 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF81 | zinc finger protein 81 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACPP | acid phosphatase, prostate |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADM | adrenomedullin |
| ADRB2 | adrenoceptor beta 2, surface |
| BAG4 | BCL2-associated athanogene 4 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| DDN | dendrin |
| DHCR24 | 24-dehydrocholesterol reductase |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNM3 | dynamin 3 |
| EFNA3 | ephrin-A3 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| FBXO31 | F-box protein 31 |
| FGL2 | fibrinogen-like 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPATCH3 | G patch domain containing 3 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HOXA5 | homeobox A5 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGFLR1 | IGF-like family receptor 1 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| ITGB7 | integrin, beta 7 |
| KIF13B | kinesin family member 13B |
| KLHL21 | kelch-like family member 21 |
| KLHL28 | kelch-like family member 28 |
| LHFP | lipoma HMGIC fusion partner |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NCALD | neurocalcin delta |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NCKAP1L | NCK-associated protein 1-like |
| NDRG1 | N-myc downstream regulated 1 |
| NFE2 | nuclear factor, erythroid 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PANX1 | pannexin 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCD1 | phospholipase C, delta 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PODXL2 | podocalyxin-like 2 |
| PORCN | porcupine homolog (Drosophila) |
| PYGB | phosphorylase, glycogen; brain |
| RAB17 | RAB17, member RAS oncogene family |
| RAB33A | RAB33A, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| REC8 | REC8 meiotic recombination protein |
| RGS13 | regulator of G-protein signaling 13 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RUSC2 | RUN and SH3 domain containing 2 |
| RWDD2A | RWD domain containing 2A |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SETD1A | SET domain containing 1A |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCTA | T-cell leukemia translocation altered |
| THEM6 | thioesterase superfamily member 6 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM177 | transmembrane protein 177 |
| TMEM45A | transmembrane protein 45A |
| TRIM45 | tripartite motif containing 45 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UNC119 | unc-119 homolog (C. elegans) |
| UPK3A | uroplakin 3A |
| USB1 | U6 snRNA biogenesis 1 |
| USP6 | ubiquitin specific peptidase 6 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF345 | zinc finger protein 345 |
| ZNF395 | zinc finger protein 395 |
| ZNF804A | zinc finger protein 804A |
| ZNF862 | zinc finger protein 862 |