| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the nifuroxazide-2850 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANXA1 | annexin A1 |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BIN1 | bridging integrator 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CDK20 | cyclin-dependent kinase 20 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDN1 | claudin 1 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CNTN1 | contactin 1 |
| CTBS | chitobiase, di-N-acetyl- |
| CTGF | connective tissue growth factor |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR1 | early growth response 1 |
| FAM49B | family with sequence similarity 49, member B |
| FLCN | folliculin |
| FOXO1 | forkhead box O1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPR87 | G protein-coupled receptor 87 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMOX1 | heme oxygenase 1 |
| HOXB5 | homeobox B5 |
| IDS | iduronate 2-sulfatase |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| INHBE | inhibin, beta E |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| JUN | jun proto-oncogene |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOXL2 | lysyl oxidase-like 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED6 | mediator complex subunit 6 |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPC1 | Niemann-Pick disease, type C1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSER1 | oxidative stress responsive serine-rich 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RBFA | ribosome binding factor A (putative) |
| RGS14 | regulator of G-protein signaling 14 |
| RGS20 | regulator of G-protein signaling 20 |
| RNF39 | ring finger protein 39 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SQSTM1 | sequestosome 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TMEM63A | transmembrane protein 63A |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM16 | tripartite motif containing 16 |
| TUBA3C | tubulin, alpha 3c |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| WEE1 | WEE1 G2 checkpoint kinase |
| ZNF484 | zinc finger protein 484 |
| ZNF652 | zinc finger protein 652 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACVR2B | activin A receptor, type IIB |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ATXN2 | ataxin 2 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| BMP5 | bone morphogenetic protein 5 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCNO | cyclin O |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC25A | cell division cycle 25A |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP170B | centrosomal protein 170B |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHPF | chondroitin polymerizing factor |
| COL9A2 | collagen, type IX, alpha 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DENND4A | DENN/MADD domain containing 4A |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DVL1 | dishevelled segment polarity protein 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM46C | family with sequence similarity 46, member C |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GATA4 | GATA binding protein 4 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HOXC6 | homeobox C6 |
| HSPA2 | heat shock 70kDa protein 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI35 | interferon-induced protein 35 |
| IL17RB | interleukin 17 receptor B |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRX4 | iroquois homeobox 4 |
| IRX5 | iroquois homeobox 5 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0319L | KIAA0319-like |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRRC20 | leucine rich repeat containing 20 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MFAP2 | microfibrillar-associated protein 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NBEAL2 | neurobeachin-like 2 |
| NMU | neuromedin U |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OLFML3 | olfactomedin-like 3 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLD2 | phospholipase D2 |
| PRR4 | proline rich 4 (lacrimal) |
| RAB30 | RAB30, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| STK11 | serine/threonine kinase 11 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBX19 | T-box 19 |
| TH | tyrosine hydroxylase |
| TNS2 | tensin 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TUBG2 | tubulin, gamma 2 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP18 | ubiquitin specific peptidase 18 |
| VASH2 | vasohibin 2 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR4 | WD repeat domain 4 |
| WDR62 | WD repeat domain 62 |
| WLS | wntless Wnt ligand secretion mediator |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFC3H1 | zinc finger, C3H1-type containing |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF552 | zinc finger protein 552 |
