| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the nifurtimox-2908 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTN1 | actinin, alpha 1 |
| ACVR1B | activin A receptor, type IB |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| AQP4 | aquaporin 4 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| BSPRY | B-box and SPRY domain containing |
| BTBD18 | BTB (POZ) domain containing 18 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA11 | carbonic anhydrase XI |
| CAMKV | CaM kinase-like vesicle-associated |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| EFNA4 | ephrin-A4 |
| ERICH1 | glutamate-rich 1 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EXPH5 | exophilin 5 |
| FABP2 | fatty acid binding protein 2, intestinal |
| FAS | Fas cell surface death receptor |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FST | follistatin |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GLRX | glutaredoxin (thioltransferase) |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GTPBP1 | GTP binding protein 1 |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HOMER3 | homer scaffolding protein 3 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFT27 | intraflagellar transport 27 |
| INO80B | INO80 complex subunit B |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIAA0355 | KIAA0355 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LIMK1 | LIM domain kinase 1 |
| LRRC6 | leucine rich repeat containing 6 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MTAP | methylthioadenosine phosphorylase |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDRG2 | NDRG family member 2 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NLE1 | notchless homolog 1 (Drosophila) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| OVOL2 | ovo-like zinc finger 2 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PAX5 | paired box 5 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE8B | phosphodiesterase 8B |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PTEN | phosphatase and tensin homolog |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PVR | poliovirus receptor |
| RAB3A | RAB3A, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RGS14 | regulator of G-protein signaling 14 |
| RIN2 | Ras and Rab interactor 2 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A13 | S100 calcium binding protein A13 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| THAP9 | THAP domain containing 9 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TSC2 | tuberous sclerosis 2 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WDR59 | WD repeat domain 59 |
| XAB2 | XPA binding protein 2 |
| ZNF234 | zinc finger protein 234 |
| ZNF574 | zinc finger protein 574 |
| ZNF639 | zinc finger protein 639 |
| ZNF688 | zinc finger protein 688 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| ANKRD40 | ankyrin repeat domain 40 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BEND5 | BEN domain containing 5 |
| BNC2 | basonuclin 2 |
| BPI | bactericidal/permeability-increasing protein |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CBR3 | carbonyl reductase 3 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC85C | coiled-coil domain containing 85C |
| CD37 | CD37 molecule |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC2D | C-type lectin domain family 2, member D |
| CRY2 | cryptochrome circadian clock 2 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EGR2 | early growth response 2 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EVL | Enah/Vasp-like |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM127B | family with sequence similarity 127, member B |
| FAM204A | family with sequence similarity 204, member A |
| FANCC | Fanconi anemia, complementation group C |
| FCHSD2 | FCH and double SH3 domains 2 |
| GALK1 | galactokinase 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRAMD1B | GRAM domain containing 1B |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4D | histone cluster 1, H4d |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGA10 | integrin, alpha 10 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| LIMD2 | LIM domain containing 2 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC157562 | uncharacterized LOC157562 |
| LOC729164 | hCG1732469 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MANSC1 | MANSC domain containing 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MKL2 | MKL/myocardin-like 2 |
| MYO1E | myosin IE |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OXTR | oxytocin receptor |
| PADI2 | peptidyl arginine deiminase, type II |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCL1 | phospholipase C-like 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMP22 | peripheral myelin protein 22 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLL | polymerase (DNA directed), lambda |
| PPT2 | palmitoyl-protein thioesterase 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS13 | regulator of G-protein signaling 13 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STX1A | syntaxin 1A (brain) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEC | tec protein tyrosine kinase |
| THAP10 | THAP domain containing 10 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TOM1 | target of myb1 (chicken) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUFT1 | tuftelin 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| ZNF250 | zinc finger protein 250 |
