| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nifurtimox-4953 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AIF1 | allograft inflammatory factor 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATF5 | activating transcription factor 5 |
| AUTS2 | autism susceptibility candidate 2 |
| BMP5 | bone morphogenetic protein 5 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CABIN1 | calcineurin binding protein 1 |
| CALML5 | calmodulin-like 5 |
| CBX4 | chromobox homolog 4 |
| CD70 | CD70 molecule |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL11A2 | collagen, type XI, alpha 2 |
| CXXC4 | CXXC finger protein 4 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| FAM174B | family with sequence similarity 174, member B |
| FAM182A | family with sequence similarity 182, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO40 | F-box protein 40 |
| FLOT1 | flotillin 1 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FRZB | frizzled-related protein |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GAS6 | growth arrest-specific 6 |
| GPR137 | G protein-coupled receptor 137 |
| GRM6 | glutamate receptor, metabotropic 6 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXB2 | homeobox B2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HPN | hepsin |
| ICAM1 | intercellular adhesion molecule 1 |
| IDUA | iduronidase, alpha-L- |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF1 | interferon regulatory factor 1 |
| ITGA8 | integrin, alpha 8 |
| JMJD4 | jumonji domain containing 4 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0319L | KIAA0319-like |
| LAMC2 | laminin, gamma 2 |
| LPL | lipoprotein lipase |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MST1 | macrophage stimulating 1 |
| NAG18 | NAG18 mRNA |
| NEFM | neurofilament, medium polypeptide |
| NME5 | NME/NM23 family member 5 |
| NOL12 | nucleolar protein 12 |
| OLFML2A | olfactomedin-like 2A |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCNX | pecanex homolog (Drosophila) |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PIP | prolactin-induced protein |
| PKP1 | plakophilin 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RPLP2 | ribosomal protein, large, P2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A2 | S100 calcium binding protein A2 |
| SCG2 | secretogranin II |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYN2 | synapsin II |
| TCF4 | transcription factor 4 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPMT | thiopurine S-methyltransferase |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VPS9D1 | VPS9 domain containing 1 |
| WSCD1 | WSC domain containing 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACYP2 | acylphosphatase 2, muscle type |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BAG4 | BCL2-associated athanogene 4 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC186 | coiled-coil domain containing 186 |
| CCNT1 | cyclin T1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHEK2 | checkpoint kinase 2 |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEAF1 | DEAF1 transcription factor |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EFHD2 | EF-hand domain family, member D2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC4 | excision repair cross-complementation group 4 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP5 | FK506 binding protein 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GATA4 | GATA binding protein 4 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR157 | G protein-coupled receptor 157 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMBOX1 | homeobox containing 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGA10 | integrin, alpha 10 |
| JUNB | jun B proto-oncogene |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MCC | mutated in colorectal cancers |
| MDM4 | MDM4, p53 regulator |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTMR12 | myotubularin related protein 12 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYO1E | myosin IE |
| NCSTN | nicastrin |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| PARD6B | par-6 family cell polarity regulator beta |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGBD5 | piggyBac transposable element derived 5 |
| PGP | phosphoglycolate phosphatase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLCD1 | phospholipase C, delta 1 |
| PLD2 | phospholipase D2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRPH | peripherin |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PVRL3 | poliovirus receptor-related 3 |
| RNF113A | ring finger protein 113A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| THBS3 | thrombospondin 3 |
| TMEM104 | transmembrane protein 104 |
| TOM1 | target of myb1 (chicken) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF211 | zinc finger protein 211 |
| ZNF747 | zinc finger protein 747 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
