| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the nifurtimox-6608 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADH6 | alcohol dehydrogenase 6 (class V) |
| AIM2 | absent in melanoma 2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATXN2L | ataxin 2-like |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTG2 | BTG family, member 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CD6 | CD6 molecule |
| CD7 | CD7 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL4A6 | collagen, type IV, alpha 6 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CST4 | cystatin S |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DICER1 | dicer 1, ribonuclease type III |
| DSG3 | desmoglein 3 |
| EPHA7 | EPH receptor A7 |
| FAM46C | family with sequence similarity 46, member C |
| FBXO31 | F-box protein 31 |
| FLT1 | fms-related tyrosine kinase 1 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| HIST1H2BM | histone cluster 1, H2bm |
| HLA-DOB | major histocompatibility complex, class II, DO beta |
| HMG20B | high mobility group 20B |
| HSF1 | heat shock transcription factor 1 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IL17RB | interleukin 17 receptor B |
| IL1R2 | interleukin 1 receptor, type II |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGB8 | integrin, beta 8 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KALRN | kalirin, RhoGEF kinase |
| KDM6B | lysine (K)-specific demethylase 6B |
| KIAA1109 | KIAA1109 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| MAG | myelin associated glycoprotein |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MEP1B | meprin A, beta |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NEBL | nebulette |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPR1 | natriuretic peptide receptor 1 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NPY | neuropeptide Y |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRF1 | nuclear respiratory factor 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHA9 | protocadherin alpha 9 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLAC4 | placenta-specific 4 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRKCA | protein kinase C, alpha |
| PRPH | peripherin |
| PRR5L | proline rich 5 like |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| REEP2 | receptor accessory protein 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RNASEH2B | ribonuclease H2, subunit B |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| SERHL2 | serine hydrolase-like 2 |
| SLC4A5 | solute carrier family 4 (sodium bicarbonate cotransporter), member 5 |
| SMC1A | structural maintenance of chromosomes 1A |
| SMCP | sperm mitochondria-associated cysteine-rich protein |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| STAB2 | stabilin 2 |
| STK38 | serine/threonine kinase 38 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
| TBX5 | T-box 5 |
| TCF3 | transcription factor 3 |
| TMEM206 | transmembrane protein 206 |
| TMOD1 | tropomodulin 1 |
| TNN | tenascin N |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| XAF1 | XIAP associated factor 1 |
| XDH | xanthine dehydrogenase |
| YBX2 | Y box binding protein 2 |
| ZNF236 | zinc finger protein 236 |
| ZNF407 | zinc finger protein 407 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALS2CL | ALS2 C-terminal like |
| ANGPTL4 | angiopoietin-like 4 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARRB2 | arrestin, beta 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CHMP1A | charged multivesicular body protein 1A |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMTN | dematin actin binding protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 |
| EVPL | envoplakin |
| FAM53B | family with sequence similarity 53, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBRS | fibrosin |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FNTB | farnesyltransferase, CAAX box, beta |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H2AK | histone cluster 1, H2ak |
| HYI | hydroxypyruvate isomerase (putative) |
| INO80D | INO80 complex subunit D |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMC3 | laminin, gamma 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LYPD3 | LY6/PLAUR domain containing 3 |
| LYRM9 | LYR motif containing 9 |
| MB | myoglobin |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1HL1 | metallothionein 1H-like 1 |
| NAG18 | NAG18 mRNA |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| ONECUT2 | one cut homeobox 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PC | pyruvate carboxylase |
| PDZD2 | PDZ domain containing 2 |
| PDZK1 | PDZ domain containing 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLL | polymerase (DNA directed), lambda |
| RNF39 | ring finger protein 39 |
| RPGRIP1L | RPGRIP1-like |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| RWDD2A | RWD domain containing 2A |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM212 | transmembrane protein 212 |
| TOLLIP | toll interacting protein |
| TPCN1 | two pore segment channel 1 |
| TRIM21 | tripartite motif containing 21 |
| TRIM62 | tripartite motif containing 62 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VNN1 | vanin 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XYLT2 | xylosyltransferase II |
| YIPF1 | Yip1 domain family, member 1 |
| YOD1 | YOD1 deubiquitinase |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF276 | zinc finger protein 276 |
| ZNF510 | zinc finger protein 510 |
| ZNF528 | zinc finger protein 528 |
