| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the nifurtimox-7328 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| B9D2 | B9 protein domain 2 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BRSK2 | BR serine/threonine kinase 2 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC186 | coiled-coil domain containing 186 |
| CDC25C | cell division cycle 25C |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EEA1 | early endosome antigen 1 |
| EFNA3 | ephrin-A3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| FADS3 | fatty acid desaturase 3 |
| FAM65A | family with sequence similarity 65, member A |
| FGFR4 | fibroblast growth factor receptor 4 |
| FST | follistatin |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GOLGA2 | golgin A2 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| HFE | hemochromatosis |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HLA-C | major histocompatibility complex, class I, C |
| HNMT | histamine N-methyltransferase |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| IFI35 | interferon-induced protein 35 |
| IFT54 | intraflagellar transport 54 |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IPP | intracisternal A particle-promoted polypeptide |
| IQCG | IQ motif containing G |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KLK2 | kallikrein-related peptidase 2 |
| LOC257152 | uncharacterized LOC257152 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTA1 | metastasis associated 1 |
| MTMR8 | myotubularin related protein 8 |
| MYO1B | myosin IB |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLXNA3 | plexin A3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PXN | paxillin |
| RAB11B | RAB11B, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNX1 | runt-related transcription factor 1 |
| SASH1 | SAM and SH3 domain containing 1 |
| SBF1 | SET binding factor 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEC24D | SEC24 family member D |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SH3BP2 | SH3-domain binding protein 2 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SRI | sorcin |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STMN1 | stathmin 1 |
| TADA3 | transcriptional adaptor 3 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMOD1 | tropomodulin 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| USP20 | ubiquitin specific peptidase 20 |
| UTRN | utrophin |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF223 | zinc finger protein 223 |
| ZNF224 | zinc finger protein 224 |
| ZNF440 | zinc finger protein 440 |
| ZNF532 | zinc finger protein 532 |
| ZNF74 | zinc finger protein 74 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APH1B | APH1B gamma secretase subunit |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC25 | coiled-coil domain containing 25 |
| CENPQ | centromere protein Q |
| CLDN15 | claudin 15 |
| CLK3 | CDC-like kinase 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CUEDC1 | CUE domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FANCE | Fanconi anemia, complementation group E |
| FBRS | fibrosin |
| FBXO31 | F-box protein 31 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLJ22184 | |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPATCH2L | G patch domain containing 2-like |
| HIST1H1D | histone cluster 1, H1d |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL4R | interleukin 4 receptor |
| IPO8 | importin 8 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LAMA3 | laminin, alpha 3 |
| LAMB3 | laminin, beta 3 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINS | lines homolog (Drosophila) |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCC | mutated in colorectal cancers |
| MED4 | mediator complex subunit 4 |
| MPG | N-methylpurine-DNA glycosylase |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO1E | myosin IE |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRX1 | NLR family member X1 |
| NRSN2 | neurensin 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| SDC3 | syndecan 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRT2 | sirtuin 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TAOK1 | TAO kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCTN2 | tectonic family member 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM183A | transmembrane protein 183A |
| TRAIP | TRAF interacting protein |
| TRIM25 | tripartite motif containing 25 |
| TRIM5 | tripartite motif containing 5 |
| TSPYL2 | TSPY-like 2 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| ZNF141 | zinc finger protein 141 |
| ZNF205 | zinc finger protein 205 |
| ZNF428 | zinc finger protein 428 |
| ZNF506 | zinc finger protein 506 |
| ZNF747 | zinc finger protein 747 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
