nilutamide-3104 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nilutamide-3104 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ACSM1 acyl-CoA synthetase medium-chain family member 1
ARMC9 armadillo repeat containing 9
ARRB1 arrestin, beta 1
ATF5 activating transcription factor 5
ATF7IP activating transcription factor 7 interacting protein
ATG10 autophagy related 10
BAGE B melanoma antigen
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BHMT2 betaine--homocysteine S-methyltransferase 2
C8B complement component 8, beta polypeptide
CCDC85B coiled-coil domain containing 85B
CD59 CD59 molecule, complement regulatory protein
CDR2L cerebellar degeneration-related protein 2-like
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP41 centrosomal protein 41kDa
CLCN7 chloride channel, voltage-sensitive 7
CLTC clathrin, heavy chain (Hc)
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CREBBP CREB binding protein
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DICER1 dicer 1, ribonuclease type III
DLC1 DLC1 Rho GTPase activating protein
DNAH17 dynein, axonemal, heavy chain 17
EPHB4 EPH receptor B4
EPS8L1 EPS8-like 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM76A family with sequence similarity 76, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXL8 F-box and leucine-rich repeat protein 8
FGF6 fibroblast growth factor 6
FST follistatin
GAREM GRB2 associated, regulator of MAPK1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAB1 B1 for mucin
HIC2 hypermethylated in cancer 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IL1R2 interleukin 1 receptor, type II
IQSEC2 IQ motif and Sec7 domain 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
LDLR low density lipoprotein receptor
LIG3 ligase III, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMS2 LIM and senescent cell antigen-like domains 2
LOC100131532 uncharacterized LOC100131532
LTBP1 latent transforming growth factor beta binding protein 1
MAOA monoamine oxidase A
MAP4 microtubule-associated protein 4
MCM3AP minichromosome maintenance complex component 3 associated protein
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MNMIP1 manchette microtubule inner protein 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NCAM1 neural cell adhesion molecule 1
NF2 neurofibromin 2 (merlin)
OLIG2 oligodendrocyte lineage transcription factor 2
PGAP3 post-GPI attachment to proteins 3
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKCH protein kinase C, eta
PSEN2 presenilin 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PURG purine-rich element binding protein G
RAB13 RAB13, member RAS oncogene family
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS5 regulator of G-protein signaling 5
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RUNDC3A RUN domain containing 3A
RUNX2 runt-related transcription factor 2
SAFB scaffold attachment factor B
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SIK1 salt-inducible kinase 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLITRK5 SLIT and NTRK-like family, member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNPH syntaphilin
SPDEF SAM pointed domain containing ETS transcription factor
TAOK2 TAO kinase 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
THBS1 thrombospondin 1
TMC7 transmembrane channel-like 7
TNN tenascin N
TONSL tonsoku-like, DNA repair protein
TRAF4 TNF receptor-associated factor 4
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TYMP thymidine phosphorylase
TYRO3 TYRO3 protein tyrosine kinase
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP53 ubiquitin specific peptidase 53
VCX2 variable charge, X-linked 2
XYLB xylulokinase homolog (H. influenzae)
ZNF471 zinc finger protein 471
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANXA2P3 annexin A2 pseudogene 3
BANK1 B-cell scaffold protein with ankyrin repeats 1
BTF3P11 basic transcription factor 3 pseudogene 11
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CD34 CD34 molecule
CDO1 cysteine dioxygenase type 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP170B centrosomal protein 170B
CEP97 centrosomal protein 97kDa
CHML choroideremia-like (Rab escort protein 2)
CHPF chondroitin polymerizing factor
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPA2 carboxypeptidase A2 (pancreatic)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPNE1 copine I
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DENND5B DENN/MADD domain containing 5B
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDAR ectodysplasin A receptor
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM127B family with sequence similarity 127, member B
FAM13C family with sequence similarity 13, member C
FAM49A family with sequence similarity 49, member A
FKBP9 FK506 binding protein 9, 63 kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FRS3 fibroblast growth factor receptor substrate 3
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH2L G patch domain containing 2-like
GPR132 G protein-coupled receptor 132
GPR27 G protein-coupled receptor 27
GPR3 G protein-coupled receptor 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1B histone cluster 1, H1b
HIST1H2BJ histone cluster 1, H2bj
HIST2H2AA3 histone cluster 2, H2aa3
HLA-DMB major histocompatibility complex, class II, DM beta
HYAL3 hyaluronoglucosaminidase 3
IDI2-AS1 IDI2 antisense RNA 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
KIF24 kinesin family member 24
KIFC3 kinesin family member C3
KPTN kaptin (actin binding protein)
KRT8P12 keratin 8 pseudogene 12
LOC730101 uncharacterized LOC730101
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K7CL MAP3K7 C-terminal like
MEFV Mediterranean fever
MYO1E myosin IE
NAG18 NAG18 mRNA
NINJ2 ninjurin 2
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NT5C 5', 3'-nucleotidase, cytosolic
NUBP2 nucleotide binding protein 2
PAQR4 progestin and adipoQ receptor family member IV
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGP phosphoglycolate phosphatase
PLA2G15 phospholipase A2, group XV
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB17 RAB17, member RAS oncogene family
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINT1 serine peptidase inhibitor, Kunitz type 1
STBD1 starch binding domain 1
STX1A syntaxin 1A (brain)
THEM6 thioesterase superfamily member 6
TRAF1 TNF receptor-associated factor 1
TSPAN32 tetraspanin 32
TUBG2 tubulin, gamma 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR62 WD repeat domain 62
ZNF280B zinc finger protein 280B
ZNF32 zinc finger protein 32
ZNF34 zinc finger protein 34
ZNHIT2 zinc finger, HIT-type containing 2