nilutamide-6481 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nilutamide-6481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADD2 adducin 2 (beta)
AJAP1 adherens junctions associated protein 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
BEGAIN brain-enriched guanylate kinase-associated
C2ORF27A chromosome 2 open reading frame 27A
C6ORF10 chromosome 6 open reading frame 10
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACTIN cactin, spliceosome C complex subunit
CBX8 chromobox homolog 8
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD82 CD82 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDY1 chromodomain protein, Y-linked, 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COMT catechol-O-methyltransferase
DESI2 desumoylating isopeptidase 2
DFNB31 deafness, autosomal recessive 31
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIO2 deiodinase, iodothyronine, type II
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DVL3 dishevelled segment polarity protein 3
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
ERN1 endoplasmic reticulum to nucleus signaling 1
FKBP10 FK506 binding protein 10, 65 kDa
FRMD4A FERM domain containing 4A
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB3 gap junction protein, beta 3, 31kDa
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GPR45 G protein-coupled receptor 45
GPSM3 G-protein signaling modulator 3
GRIP2 glutamate receptor interacting protein 2
HIPK2 homeodomain interacting protein kinase 2
HIST1H3E histone cluster 1, H3e
HOXA10 homeobox A10
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICA1 islet cell autoantigen 1, 69kDa
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGFBP1 insulin-like growth factor binding protein 1
IQCA1 IQ motif containing with AAA domain 1
KANK1 KN motif and ankyrin repeat domains 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KRT15 keratin 15, type I
LIN7A lin-7 homolog A (C. elegans)
LMOD1 leiomodin 1 (smooth muscle)
LOC157562 uncharacterized LOC157562
LRP12 low density lipoprotein receptor-related protein 12
MANBA mannosidase, beta A, lysosomal
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MIP major intrinsic protein of lens fiber
MMP3 matrix metallopeptidase 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L1 NEDD4 binding protein 2-like 1
NADK NAD kinase
NF2 neurofibromin 2 (merlin)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NKX3-2 NK3 homeobox 2
NPY4R neuropeptide Y receptor Y4
PALM paralemmin
PARVB parvin, beta
PAX2 paired box 2
PITX1 paired-like homeodomain 1
POU6F2 POU class 6 homeobox 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PROM1 prominin 1
PTHLH parathyroid hormone-like hormone
RANBP1 RAN binding protein 1
RNF122 ring finger protein 122
RNF6 ring finger protein (C3H2C3 type) 6
SAMD4A sterile alpha motif domain containing 4A
SDC3 syndecan 3
SGCE sarcoglycan, epsilon
SH2B3 SH2B adaptor protein 3
SIX1 SIX homeobox 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TAPBP TAP binding protein (tapasin)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TENM4 teneurin transmembrane protein 4
TMEM242 transmembrane protein 242
TMEM259 transmembrane protein 259
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
UGT8 UDP glycosyltransferase 8
VAC14 Vac14 homolog (S. cerevisiae)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZFAND5 zinc finger, AN1-type domain 5
ZNF222 zinc finger protein 222
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAM15 ADAM metallopeptidase domain 15
ADTRP androgen-dependent TFPI-regulating protein
AFAP1 actin filament associated protein 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMH anti-Mullerian hormone
AMPD3 adenosine monophosphate deaminase 3
APOC4 apolipoprotein C-IV
APOD apolipoprotein D
ARC activity-regulated cytoskeleton-associated protein
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATXN2 ataxin 2
BFSP1 beaded filament structural protein 1, filensin
C10ORF95 chromosome 10 open reading frame 95
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCRL2 chemokine (C-C motif) receptor-like 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CEL carboxyl ester lipase
CHRM3 cholinergic receptor, muscarinic 3
CLDN17 claudin 17
CRLF1 cytokine receptor-like factor 1
CTSE cathepsin E
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EAF2 ELL associated factor 2
ETAA1 Ewing tumor-associated antigen 1
EXO5 exonuclease 5
F2R coagulation factor II (thrombin) receptor
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FSCN1 fascin actin-bundling protein 1
GLDC glycine dehydrogenase (decarboxylating)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AK histone cluster 1, H2ak
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
IGSF1 immunoglobulin superfamily, member 1
IL12RB1 interleukin 12 receptor, beta 1
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1456 KIAA1456
LAMP3 lysosomal-associated membrane protein 3
LOC390998 ribosomal protein L10 pseudogene
LPXN leupaxin
METTL16 methyltransferase like 16
MITF microphthalmia-associated transcription factor
MYBBP1A MYB binding protein (P160) 1a
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2L3 nuclear factor, erythroid 2-like 3
NUP62CL nucleoporin 62kDa C-terminal like
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PADI1 peptidyl arginine deiminase, type I
PCDHGB5 protocadherin gamma subfamily B, 5
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
PPT2 palmitoyl-protein thioesterase 2
PROL1 proline rich, lacrimal 1
PRSS50 protease, serine, 50
RNF2 ring finger protein 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLMO1 slowmo homolog 1 (Drosophila)
SPAG4 sperm associated antigen 4
SPATA1 spermatogenesis associated 1
STIM1 stromal interaction molecule 1
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMPRSS3 transmembrane protease, serine 3
TTC33 tetratricopeptide repeat domain 33
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR25 WD repeat domain 25
XDH xanthine dehydrogenase
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF350 zinc finger protein 350
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF480 zinc finger protein 480