nilutamide-6763 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the nilutamide-6763 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAGAB alpha- and gamma-adaptin binding protein
ADCY9 adenylate cyclase 9
AGFG1 ArfGAP with FG repeats 1
AHNAK AHNAK nucleoprotein
AIF1 allograft inflammatory factor 1
AKR1C2 aldo-keto reductase family 1, member C2
ANGPTL2 angiopoietin-like 2
ANKRD12 ankyrin repeat domain 12
ASPHD1 aspartate beta-hydroxylase domain containing 1
AURKA aurora kinase A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BEX1 brain expressed, X-linked 1
BICC1 BicC family RNA binding protein 1
BMP8B bone morphogenetic protein 8b
BST1 bone marrow stromal cell antigen 1
CACYBP calcyclin binding protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
COL4A6 collagen, type IV, alpha 6
CPB2 carboxypeptidase B2 (plasma)
CTSS cathepsin S
CUZD1 CUB and zona pellucida-like domains 1
DCTN1 dynactin 1
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAI2 dynein, axonemal, intermediate chain 2
DTNA dystrobrevin, alpha
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EIF5B eukaryotic translation initiation factor 5B
ERAP1 endoplasmic reticulum aminopeptidase 1
EZR ezrin
FAM134B family with sequence similarity 134, member B
FAM149B1 family with sequence similarity 149, member B1
FAM182B family with sequence similarity 182, member B
FBXO11 F-box protein 11
FGFR2 fibroblast growth factor receptor 2
GLP1R glucagon-like peptide 1 receptor
GRSF1 G-rich RNA sequence binding factor 1
GUK1 guanylate kinase 1
HOXD1 homeobox D1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IER3IP1 immediate early response 3 interacting protein 1
IL24 interleukin 24
ING2 inhibitor of growth family, member 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCTD14 potassium channel tetramerization domain containing 14
KIAA1024 KIAA1024
KRAS Kirsten rat sarcoma viral oncogene homolog
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MFAP3L microfibrillar-associated protein 3-like
MLANA melan-A
MLX MLX, MAX dimerization protein
MMP10 matrix metallopeptidase 10
MRPL41 mitochondrial ribosomal protein L41
MRPL52 mitochondrial ribosomal protein L52
NDN necdin, melanoma antigen (MAGE) family member
NOD1 nucleotide-binding oligomerization domain containing 1
NOP14-AS1 NOP14 antisense RNA 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OSBPL10 oxysterol binding protein-like 10
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPPA2 pappalysin 2
PGK1 phosphoglycerate kinase 1
PIGR polymeric immunoglobulin receptor
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASL12 RAS-like, family 12
RGS10 regulator of G-protein signaling 10
RGS12 regulator of G-protein signaling 12
RHEB Ras homolog enriched in brain
RIN3 Ras and Rab interactor 3
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPL13 ribosomal protein L13
RPL14 ribosomal protein L14
RPLP2 ribosomal protein, large, P2
RPS3A ribosomal protein S3A
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SSTR2 somatostatin receptor 2
TK2 thymidine kinase 2, mitochondrial
TM6SF1 transmembrane 6 superfamily member 1
TMCO6 transmembrane and coiled-coil domains 6
TRD T cell receptor delta locus
TWF1 twinfilin actin binding protein 1
TXN thioredoxin
VDAC3 voltage-dependent anion channel 3
YIPF4 Yip1 domain family, member 4
ZBTB20 zinc finger and BTB domain containing 20
ZNF268 zinc finger protein 268
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD8 abhydrolase domain containing 8
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM15 ADAM metallopeptidase domain 15
ADAM23 ADAM metallopeptidase domain 23
AES amino-terminal enhancer of split
ANXA2P3 annexin A2 pseudogene 3
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC4 apolipoprotein C-IV
ASIC1 acid sensing (proton gated) ion channel 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BMP15 bone morphogenetic protein 15
C16ORF62 chromosome 16 open reading frame 62
C7ORF69 chromosome 7 open reading frame 69
CAMKMT calmodulin-lysine N-methyltransferase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHM choroideremia (Rab escort protein 1)
CNN1 calponin 1, basic, smooth muscle
CPZ carboxypeptidase Z
DBF4B DBF4 zinc finger B
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNM3 dynamin 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ELSPBP1 epididymal sperm binding protein 1
EPHA7 EPH receptor A7
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM86B1 family with sequence similarity 86, member B1
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FRMD8 FERM domain containing 8
FRS2 fibroblast growth factor receptor substrate 2
FRS3 fibroblast growth factor receptor substrate 3
GIF gastric intrinsic factor (vitamin B synthesis)
GRM4 glutamate receptor, metabotropic 4
H1F0 H1 histone family, member 0
HDAC11 histone deacetylase 11
HHLA3 HERV-H LTR-associating 3
HIST1H2BN histone cluster 1, H2bn
HSPB6 heat shock protein, alpha-crystallin-related, B6
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KRT6A keratin 6A, type II
LMO7 LIM domain 7
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFSD6 major facilitator superfamily domain containing 6
NEUROD1 neuronal differentiation 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH12 protocadherin 12
PCSK7 proprotein convertase subtilisin/kexin type 7
PKD2L2 polycystic kidney disease 2-like 2
PKM pyruvate kinase, muscle
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLL polymerase (DNA directed), lambda
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRAMEF10 PRAME family member 10
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARS arginyl-tRNA synthetase
RNF126P1 ring finger protein 126 pseudogene 1
SCIN scinderin
SENP7 SUMO1/sentrin specific peptidase 7
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMAD7 SMAD family member 7
SNTG1 syntrophin, gamma 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SRD5A3 steroid 5 alpha-reductase 3
STEAP4 STEAP family member 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D22B TBC1 domain family, member 22B
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBXAS1 thromboxane A synthase 1 (platelet)
TLN1 talin 1
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TUBA3C tubulin, alpha 3c
UGT8 UDP glycosyltransferase 8
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YY2 YY2 transcription factor
ZFHX3 zinc finger homeobox 3
ZNF253 zinc finger protein 253
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446