| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nimesulide-1428 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTR1A | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
| ADGRG3 | adhesion G protein-coupled receptor G3 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| ANGEL1 | angel homolog 1 (Drosophila) |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACYBP | calcyclin binding protein |
| CEP152 | centrosomal protein 152kDa |
| CIITA | class II, major histocompatibility complex, transactivator |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DENND2D | DENN/MADD domain containing 2D |
| DLG1 | discs, large homolog 1 (Drosophila) |
| DUS2 | dihydrouridine synthase 2 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFCAB14 | EF-hand calcium binding domain 14 |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FBXO42 | F-box protein 42 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGFR1OP | FGFR1 oncogene partner |
| FOXN3 | forkhead box N3 |
| GAA | glucosidase, alpha; acid |
| GAB2 | GRB2-associated binding protein 2 |
| GON4L | gon-4-like (C. elegans) |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HBB | hemoglobin, beta |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| ING4 | inhibitor of growth family, member 4 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| KIFAP3 | kinesin-associated protein 3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LY9 | lymphocyte antigen 9 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 |
| MCL1 | myeloid cell leukemia 1 |
| MED16 | mediator complex subunit 16 |
| MED18 | mediator complex subunit 18 |
| MED28 | mediator complex subunit 28 |
| MINK1 | misshapen-like kinase 1 |
| NADK | NAD kinase |
| NECAP2 | NECAP endocytosis associated 2 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NOTCH2 | notch 2 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NUP160 | nucleoporin 160kDa |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PCTP | phosphatidylcholine transfer protein |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PGK1 | phosphoglycerate kinase 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTCRA | pre T-cell antigen receptor alpha |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RNF170 | ring finger protein 170 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SETD4 | SET domain containing 4 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SRR | serine racemase |
| SSH3 | slingshot protein phosphatase 3 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STX16 | syntaxin 16 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TEX2 | testis expressed 2 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAF4 | TNF receptor-associated factor 4 |
| TUBB3 | tubulin, beta 3 class III |
| VEGFA | vascular endothelial growth factor A |
| VENTX | VENT homeobox |
| YTHDC2 | YTH domain containing 2 |
| ZNF410 | zinc finger protein 410 |
| ZNF480 | zinc finger protein 480 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ABHD3 | abhydrolase domain containing 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACVR2B | activin A receptor, type IIB |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B3GNT1 | |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCDC6 | coiled-coil domain containing 6 |
| CCNT1 | cyclin T1 |
| CDC37L1 | cell division cycle 37-like 1 |
| CDC73 | cell division cycle 73 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLDN15 | claudin 15 |
| CPOX | coproporphyrinogen oxidase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DENND1A | DENN/MADD domain containing 1A |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| E2F8 | E2F transcription factor 8 |
| EMP3 | epithelial membrane protein 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| EVL | Enah/Vasp-like |
| FAM57A | family with sequence similarity 57, member A |
| FBXO5 | F-box protein 5 |
| FMNL1 | formin-like 1 |
| FOXJ2 | forkhead box J2 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KLF13 | Kruppel-like factor 13 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MAVS | mitochondrial antiviral signaling protein |
| MBTD1 | mbt domain containing 1 |
| MCM9 | minichromosome maintenance complex component 9 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NRIP3 | nuclear receptor interacting protein 3 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| PRKX | protein kinase, X-linked |
| PRMT3 | protein arginine methyltransferase 3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTOV1 | prostate tumor overexpressed 1 |
| RAB20 | RAB20, member RAS oncogene family |
| RBBP5 | retinoblastoma binding protein 5 |
| RIN1 | Ras and Rab interactor 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP1 | ribosomal RNA processing 1 |
| RWDD3 | RWD domain containing 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SEC61B | Sec61 beta subunit |
| SKI | SKI proto-oncogene |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STXBP3 | syntaxin binding protein 3 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM135 | transmembrane protein 135 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAPPC2 | trafficking protein particle complex 2 |
| TSPAN32 | tetraspanin 32 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBXN6 | UBX domain protein 6 |
| UXS1 | UDP-glucuronate decarboxylase 1 |
| WT1-AS | WT1 antisense RNA |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZNF124 | zinc finger protein 124 |
| ZNF217 | zinc finger protein 217 |
| ZNF408 | zinc finger protein 408 |
| ZNF432 | zinc finger protein 432 |
| ZNF606 | zinc finger protein 606 |
| ZNF652 | zinc finger protein 652 |
| ZNF85 | zinc finger protein 85 |
