nimesulide-2112 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the nimesulide-2112 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
APOM apolipoprotein M
APP amyloid beta (A4) precursor protein
ASB13 ankyrin repeat and SOCS box containing 13
ASB7 ankyrin repeat and SOCS box containing 7
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CADPS2 Ca++-dependent secretion activator 2
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDIP1 cell death-inducing p53 target 1
CLIC5 chloride intracellular channel 5
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSTN3 calsyntenin 3
CNTLN centlein, centrosomal protein
CYB561 cytochrome b561
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNM3 dynamin 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EP300 E1A binding protein p300
EPS8L1 EPS8-like 1
FN1 fibronectin 1
GOLGA2 golgin A2
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPR3 G protein-coupled receptor 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HN1L hematological and neurological expressed 1-like
HOMER3 homer scaffolding protein 3
HRH2 histamine receptor H2
IDI2-AS1 IDI2 antisense RNA 1
IGL immunoglobulin lambda locus
IL15 interleukin 15
ITGB5 integrin, beta 5
KIF1A kinesin family member 1A
LDB1 LIM domain binding 1
LIME1 Lck interacting transmembrane adaptor 1
LMNA lamin A/C
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC399491
LRP3 low density lipoprotein receptor-related protein 3
LYPD3 LY6/PLAUR domain containing 3
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCF2L MCF.2 cell line derived transforming sequence-like
MIIP migration and invasion inhibitory protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSX2 msh homeobox 2
NCKIPSD NCK interacting protein with SH3 domain
NOP14-AS1 NOP14 antisense RNA 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDGFB platelet-derived growth factor beta polypeptide
PKP3 plakophilin 3
PLAC4 placenta-specific 4
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRPF18 pre-mRNA processing factor 18
PWAR5 Prader Willi/Angelman region RNA 5
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RGS4 regulator of G-protein signaling 4
RHOBTB2 Rho-related BTB domain containing 2
RIF1 replication timing regulatory factor 1
RNF2 ring finger protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
SAP30 Sin3A-associated protein, 30kDa
SEZ6L seizure related 6 homolog (mouse)-like
SGSM3 small G protein signaling modulator 3
SIAH1 siah E3 ubiquitin protein ligase 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SORBS2 sorbin and SH3 domain containing 2
SOX4 SRY (sex determining region Y)-box 4
STK4 serine/threonine kinase 4
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFCP2 transcription factor CP2
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM14 tripartite motif containing 14
TRIM23 tripartite motif containing 23
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTC12 tetratricopeptide repeat domain 12
TTC38 tetratricopeptide repeat domain 38
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
VLDLR very low density lipoprotein receptor
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF277 zinc finger protein 277
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF629 zinc finger protein 629

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AEN apoptosis enhancing nuclease
ANGPTL4 angiopoietin-like 4
APOLD1 apolipoprotein L domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL2L2 BCL2-like 2
C11ORF73 chromosome 11 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
C3ORF52 chromosome 3 open reading frame 52
C9ORF3 chromosome 9 open reading frame 3
CCDC47 coiled-coil domain containing 47
CDT1 chromatin licensing and DNA replication factor 1
CFD complement factor D (adipsin)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHPF chondroitin polymerizing factor
CIDEC cell death-inducing DFFA-like effector c
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORO1A coronin, actin binding protein, 1A
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECM1 extracellular matrix protein 1
ELOVL4 ELOVL fatty acid elongase 4
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM102A family with sequence similarity 102, member A
FAM131A family with sequence similarity 131, member A
FAM160B2 family with sequence similarity 160, member B2
FKBP1B FK506 binding protein 1B, 12.6 kDa
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH1 G patch domain containing 1
GPR1 G protein-coupled receptor 1
GRPR gastrin-releasing peptide receptor
HIRA histone cell cycle regulator
HIST1H3B histone cluster 1, H3b
HOXA1 homeobox A1
IGFLR1 IGF-like family receptor 1
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0894 KIAA0894 protein
LOC100272216 uncharacterized LOC100272216
LYPD1 LY6/PLAUR domain containing 1
MNX1 motor neuron and pancreas homeobox 1
MTMR12 myotubularin related protein 12
MXRA8 matrix-remodelling associated 8
NPM3 nucleophosmin/nucleoplasmin 3
NRSN2 neurensin 2
NYNRIN NYN domain and retroviral integrase containing
ODF2 outer dense fiber of sperm tails 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PELP1 proline, glutamate and leucine rich protein 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLAC8 placenta-specific 8
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
REPS2 RALBP1 associated Eps domain containing 2
RPP25 ribonuclease P/MRP 25kDa subunit
SAMD9 sterile alpha motif domain containing 9
SETD6 SET domain containing 6
SH2D2A SH2 domain containing 2A
SKI SKI proto-oncogene
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC46A3 solute carrier family 46, member 3
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SSNA1 Sjogren syndrome nuclear autoantigen 1
ST5 suppression of tumorigenicity 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
THBS3 thrombospondin 3
TMEM159 transmembrane protein 159
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNS2 tensin 2
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TXLNG taxilin gamma
UBQLN4 ubiquilin 4
WDR18 WD repeat domain 18
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF174 zinc finger protein 174
ZNF254 zinc finger protein 254
ZNF551 zinc finger protein 551
ZNF571 zinc finger protein 571
ZNF606 zinc finger protein 606
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862
ZNRD1-AS1 ZNRD1 antisense RNA 1