nimodipine-3103 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nimodipine-3103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD2 abhydrolase domain containing 2
ACVR1B activin A receptor, type IB
ANGPTL2 angiopoietin-like 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BNC2 basonuclin 2
BTD biotinidase
BTF3P11 basic transcription factor 3 pseudogene 11
BTN2A2 butyrophilin, subfamily 2, member A2
C1ORF61 chromosome 1 open reading frame 61
CALML3 calmodulin-like 3
CCDC71 coiled-coil domain containing 71
CLCN7 chloride channel, voltage-sensitive 7
COPE coatomer protein complex, subunit epsilon
CREM cAMP responsive element modulator
CTAG2 cancer/testis antigen 2
CXCR3 chemokine (C-X-C motif) receptor 3
CYB561 cytochrome b561
DLG5 discs, large homolog 5 (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DOCK4 dedicator of cytokinesis 4
DPEP2 dipeptidase 2
DUSP4 dual specificity phosphatase 4
EFR3B EFR3 homolog B (S. cerevisiae)
FBXO31 F-box protein 31
FLOT1 flotillin 1
FPR2 formyl peptide receptor 2
FRMD4B FERM domain containing 4B
FTH1 ferritin, heavy polypeptide 1
GNLY granulysin
GPR15 G protein-coupled receptor 15
GPR68 G protein-coupled receptor 68
HCG4 HLA complex group 4 (non-protein coding)
HNMT histamine N-methyltransferase
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R2 interleukin 1 receptor, type II
IL21R interleukin 21 receptor
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIAA0226L KIAA0226-like
KRT8P12 keratin 8 pseudogene 12
KYNU kynureninase
LAMB3 laminin, beta 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MOB3B MOB kinase activator 3B
MPPE1 metallophosphoesterase 1
MSH3 mutS homolog 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXRA8 matrix-remodelling associated 8
NBPF10 neuroblastoma breakpoint family, member 10
NPPA natriuretic peptide A
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRG1 neuregulin 1
NUP188 nucleoporin 188kDa
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PADI1 peptidyl arginine deiminase, type I
PAOX polyamine oxidase (exo-N4-amino)
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRKCH protein kinase C, eta
RAB33A RAB33A, member RAS oncogene family
REC8 REC8 meiotic recombination protein
ROM1 retinal outer segment membrane protein 1
SDC2 syndecan 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH2D2A SH2 domain containing 2A
SIGLEC7 sialic acid binding Ig-like lectin 7
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIX3 SIX homeobox 3
SLC25A30 solute carrier family 25, member 30
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35F5 solute carrier family 35, member F5
SORBS3 sorbin and SH3 domain containing 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX6 T-box 6
TCP10L t-complex 10-like
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS1 thrombospondin 1
TK2 thymidine kinase 2, mitochondrial
TPMT thiopurine S-methyltransferase
TTLL1 tubulin tyrosine ligase-like family member 1
TYMP thymidine phosphorylase
ZC3H13 zinc finger CCCH-type containing 13
ZFPL1 zinc finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF185 zinc finger protein 185 (LIM domain)
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ATXN2 ataxin 2
B3GNT1
BAHCC1 BAH domain and coiled-coil containing 1
BEND5 BEN domain containing 5
BHLHE41 basic helix-loop-helix family, member e41
C16ORF59 chromosome 16 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
CES3 carboxylesterase 3
COL9A2 collagen, type IX, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND5B DENN/MADD domain containing 5B
DPY19L2P2 DPY19L2 pseudogene 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F1 E2F transcription factor 1
ECI2 enoyl-CoA delta isomerase 2
EMILIN2 elastin microfibril interfacer 2
ENO3 enolase 3 (beta, muscle)
FAM127B family with sequence similarity 127, member B
FAM184A family with sequence similarity 184, member A
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FOSL1 FOS-like antigen 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GDAP1 ganglioside induced differentiation associated protein 1
GPATCH2L G patch domain containing 2-like
GPHN gephyrin
GPR27 G protein-coupled receptor 27
GTPBP6 GTP binding protein 6 (putative)
HCAR3 hydroxycarboxylic acid receptor 3
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HRAS Harvey rat sarcoma viral oncogene homolog
IFITM3 interferon induced transmembrane protein 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP5 lysosomal-associated membrane protein family, member 5
LAS1L LAS1-like (S. cerevisiae)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LINC00260 long intergenic non-protein coding RNA 260
LTBP2 latent transforming growth factor beta binding protein 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MED22 mediator complex subunit 22
MLPH melanophilin
MRPL4 mitochondrial ribosomal protein L4
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOL10 nucleolar protein 10
NOL6 nucleolar protein 6 (RNA-associated)
PLA2G15 phospholipase A2, group XV
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PNMA1 paraneoplastic Ma antigen 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RBM42 RNA binding motif protein 42
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF122 ring finger protein 122
RPA4 replication protein A4, 30kDa
RPAP1 RNA polymerase II associated protein 1
SCG5 secretogranin V
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SPATS2 spermatogenesis associated, serine-rich 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRN striatin, calmodulin binding protein
TBXAS1 thromboxane A synthase 1 (platelet)
TEC tec protein tyrosine kinase
THBS4 thrombospondin 4
THEM6 thioesterase superfamily member 6
TM9SF4 transmembrane 9 superfamily protein member 4
TMEM212 transmembrane protein 212
TPM3 tropomyosin 3
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM26 tripartite motif containing 26
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPYL2 TSPY-like 2
TUBG2 tubulin, gamma 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WDR76 WD repeat domain 76
WT1-AS WT1 antisense RNA
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YOD1 YOD1 deubiquitinase
ZNF10 zinc finger protein 10
ZNF862 zinc finger protein 862