nimodipine-5421 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nimodipine-5421 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN4 actinin, alpha 4
ADCK2 aarF domain containing kinase 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AMPD3 adenosine monophosphate deaminase 3
ARL3 ADP-ribosylation factor-like 3
ASPH aspartate beta-hydroxylase
ATP10B ATPase, class V, type 10B
C1ORF105 chromosome 1 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CARD10 caspase recruitment domain family, member 10
CBX8 chromobox homolog 8
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CEP112 centrosomal protein 112kDa
CLCA2 chloride channel accessory 2
CLDN15 claudin 15
CLMN calmin (calponin-like, transmembrane)
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CORT cortistatin
CRAT carnitine O-acetyltransferase
CYTH1 cytohesin 1
DMXL2 Dmx-like 2
DOK5 docking protein 5
DSPP dentin sialophosphoprotein
DTNA dystrobrevin, alpha
ECE1 endothelin converting enzyme 1
EDNRA endothelin receptor type A
EHD2 EH-domain containing 2
EVA1B eva-1 homolog B (C. elegans)
FBXO11 F-box protein 11
FDX1 ferredoxin 1
FECH ferrochelatase
FH fumarate hydratase
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GJA4 gap junction protein, alpha 4, 37kDa
GLG1 golgi glycoprotein 1
GM2A GM2 ganglioside activator
GPALPP1 GPALPP motifs containing 1
HIST1H1B histone cluster 1, H1b
HRASLS2 HRAS-like suppressor 2
IGL immunoglobulin lambda locus
ITM2C integral membrane protein 2C
JMJD4 jumonji domain containing 4
KIAA1109 KIAA1109
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF13 Kruppel-like factor 13
KLHL20 kelch-like family member 20
LIN7B lin-7 homolog B (C. elegans)
LINC00260 long intergenic non-protein coding RNA 260
LMAN1 lectin, mannose-binding, 1
LONP2 lon peptidase 2, peroxisomal
LRP12 low density lipoprotein receptor-related protein 12
MAP2K5 mitogen-activated protein kinase kinase 5
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MORC2 MORC family CW-type zinc finger 2
MSC musculin
N4BP2L1 NEDD4 binding protein 2-like 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NOS1 nitric oxide synthase 1 (neuronal)
NRSN2 neurensin 2
NT5M 5',3'-nucleotidase, mitochondrial
OGFR opioid growth factor receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCLO piccolo presynaptic cytomatrix protein
PDE3B phosphodiesterase 3B, cGMP-inhibited
PLAU plasminogen activator, urokinase
POLM polymerase (DNA directed), mu
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPP5C protein phosphatase 5, catalytic subunit
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PVR poliovirus receptor
RAB30 RAB30, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
S100A11 S100 calcium binding protein A11
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SFTPB surfactant protein B
SIK3 SIK family kinase 3
SKAP1 src kinase associated phosphoprotein 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOX4 SRY (sex determining region Y)-box 4
STK3 serine/threonine kinase 3
TBX2 T-box 2
TESK1 testis-specific kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WNK1 WNK lysine deficient protein kinase 1
WNT5A wingless-type MMTV integration site family, member 5A
XYLB xylulokinase homolog (H. influenzae)

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
APOD apolipoprotein D
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC4 armadillo repeat containing 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BATF basic leucine zipper transcription factor, ATF-like
BST2 bone marrow stromal cell antigen 2
BTF3P11 basic transcription factor 3 pseudogene 11
CA5BP1 carbonic anhydrase VB pseudogene 1
CD8A CD8a molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHM choroideremia (Rab escort protein 1)
CIC capicua transcriptional repressor
CLCN2 chloride channel, voltage-sensitive 2
CLEC4E C-type lectin domain family 4, member E
CLIC2 chloride intracellular channel 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CTSF cathepsin F
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAH17 dynein, axonemal, heavy chain 17
DPY19L1P1 DPY19L1 pseudogene 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
ETV7 ets variant 7
EXD3 exonuclease 3'-5' domain containing 3
FADS2 fatty acid desaturase 2
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GDAP1 ganglioside induced differentiation associated protein 1
GNL1 guanine nucleotide binding protein-like 1
GRTP1 growth hormone regulated TBC protein 1
GSTTP1 glutathione S-transferase theta pseudogene 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AK histone cluster 1, H2ak
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HOXC5 homeobox C5
IFI27 interferon, alpha-inducible protein 27
IRF9 interferon regulatory factor 9
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KDM7A lysine (K)-specific demethylase 7A
KIF13B kinesin family member 13B
LZTR1 leucine-zipper-like transcription regulator 1
MAK male germ cell-associated kinase
MATN3 matrilin 3
MFAP2 microfibrillar-associated protein 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRPL41 mitochondrial ribosomal protein L41
MYO1E myosin IE
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD4 neuronal differentiation 4
NLRX1 NLR family member X1
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLSCR4 phospholipid scramblase 4
PNPLA6 patatin-like phospholipase domain containing 6
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTBN5 spectrin, beta, non-erythrocytic 5
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TESC tescalcin
TFF2 trefoil factor 2
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TRPV6 transient receptor potential cation channel, subfamily V, member 6
USB1 U6 snRNA biogenesis 1
XYLT1 xylosyltransferase I
ZNF137P zinc finger protein 137, pseudogene
ZNF747 zinc finger protein 747