nimodipine-6320 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nimodipine-6320 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACOX3 acyl-CoA oxidase 3, pristanoyl
ALDOB aldolase B, fructose-bisphosphate
AOC2 amine oxidase, copper containing 2 (retina-specific)
APOM apolipoprotein M
ARID1A AT rich interactive domain 1A (SWI-like)
ASIC1 acid sensing (proton gated) ion channel 1
ASMTL acetylserotonin O-methyltransferase-like
ATN1 atrophin 1
ATXN2L ataxin 2-like
BICD1 bicaudal D homolog 1 (Drosophila)
C14ORF1 chromosome 14 open reading frame 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDC14B cell division cycle 14B
CDT1 chromatin licensing and DNA replication factor 1
CLDN17 claudin 17
CORO1A coronin, actin binding protein, 1A
CRYGC crystallin, gamma C
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSF cathepsin F
CUL7 cullin 7
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAI2 dynein, axonemal, intermediate chain 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGFR epidermal growth factor receptor
EML2 echinoderm microtubule associated protein like 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FAM174B family with sequence similarity 174, member B
FBXO31 F-box protein 31
FGF17 fibroblast growth factor 17
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAS8 growth arrest-specific 8
GLRB glycine receptor, beta
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTM5 glutathione S-transferase mu 5
GTDC1 glycosyltransferase-like domain containing 1
HFE hemochromatosis
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
INPP5J inositol polyphosphate-5-phosphatase J
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0922 KIAA0922
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LATS1 large tumor suppressor kinase 1
MAPK14 mitogen-activated protein kinase 14
MLH3 mutL homolog 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
N4BP1 NEDD4 binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBEAL2 neurobeachin-like 2
NOL12 nucleolar protein 12
NPEPL1 aminopeptidase-like 1
NPY2R neuropeptide Y receptor Y2
PAIP2B poly(A) binding protein interacting protein 2B
PALM paralemmin
PARP6 poly (ADP-ribose) polymerase family, member 6
PCNXL2 pecanex-like 2 (Drosophila)
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGPEP1 pyroglutamyl-peptidase I
PHACTR2 phosphatase and actin regulator 2
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKP4 plakophilin 4
PRDX2 peroxiredoxin 2
PTCH1 patched 1
PTPRE protein tyrosine phosphatase, receptor type, E
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGDS ral guanine nucleotide dissociation stimulator
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBM19 RNA binding motif protein 19
RNF170 ring finger protein 170
RPL10 ribosomal protein L10
SAYSD1 SAYSVFN motif domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIRT5 sirtuin 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMR3A submaxillary gland androgen regulated protein 3A
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STC1 stanniocalcin 1
STC2 stanniocalcin 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TCP11L1 t-complex 11, testis-specific-like 1
THOC5 THO complex 5
TMSB15A thymosin beta 15a
UBA7 ubiquitin-like modifier activating enzyme 7
VEZT vezatin, adherens junctions transmembrane protein
WWOX WW domain containing oxidoreductase
YIPF4 Yip1 domain family, member 4
ZMYND11 zinc finger, MYND-type containing 11
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ATAD5 ATPase family, AAA domain containing 5
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C11ORF80 chromosome 11 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
CBR4 carbonyl reductase 4
CCDC85C coiled-coil domain containing 85C
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DLL3 delta-like 3 (Drosophila)
EFNA1 ephrin-A1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EXD3 exonuclease 3'-5' domain containing 3
FADS3 fatty acid desaturase 3
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF23 fibroblast growth factor 23
FOXN2 forkhead box N2
FPGS folylpolyglutamate synthase
FUZ fuzzy planar cell polarity protein
GALT galactose-1-phosphate uridylyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTT1 glutathione S-transferase theta 1
GTPBP2 GTP binding protein 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IDI2-AS1 IDI2 antisense RNA 1
IFI30 interferon, gamma-inducible protein 30
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL15RA interleukin 15 receptor, alpha
JUNB jun B proto-oncogene
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KIAA1462 KIAA1462
LMO7 LIM domain 7
LNPEP leucyl/cystinyl aminopeptidase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP6 low density lipoprotein receptor-related protein 6
LRRC37A3 leucine rich repeat containing 37, member A3
LYRM9 LYR motif containing 9
MAPK12 mitogen-activated protein kinase 12
MAPK3 mitogen-activated protein kinase 3
MRPS18C mitochondrial ribosomal protein S18C
MUC3B mucin 3B, cell surface associated
MYO1D myosin ID
NLGN1 neuroligin 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NUPR1 nuclear protein, transcriptional regulator, 1
ONECUT2 one cut homeobox 2
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PDE12 phosphodiesterase 12
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
POM121 POM121 transmembrane nucleoporin
PRPH peripherin
PRR15L proline rich 15-like
PTGES2 prostaglandin E synthase 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCD5 stearoyl-CoA desaturase 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
SPATA7 spermatogenesis associated 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TMBIM1 transmembrane BAX inhibitor motif containing 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3D tubulin, alpha 3d
TUBA4B tubulin, alpha 4b
TUBB2B tubulin, beta 2B class IIb
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VWA1 von Willebrand factor A domain containing 1
WDR18 WD repeat domain 18
WFDC2 WAP four-disulfide core domain 2
ZBTB44 zinc finger and BTB domain containing 44
ZNF197 zinc finger protein 197
ZNF215 zinc finger protein 215
ZNF358 zinc finger protein 358
ZNF528 zinc finger protein 528
ZNF552 zinc finger protein 552
ZNF639 zinc finger protein 639
ZNF665 zinc finger protein 665
ZNF778 zinc finger protein 778
ZSCAN16 zinc finger and SCAN domain containing 16