nimodipine Gene Set

Dataset Guide to Pharmacology Chemical Ligands of Receptors
Category physical interactions
Type ligand (chemical)
Description A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm. (Chemical Entities of Biological Interest Ontology, CHEBI_7575)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2523
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Genes

4 receptors of the nimodipine ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol Name
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
NR3C2 nuclear receptor subfamily 3, group C, member 2