Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the nipecotic acid-3121 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADRA1A | adrenoceptor alpha 1A |
AFF4 | AF4/FMR2 family, member 4 |
ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
AMPH | amphiphysin |
ARSE | arylsulfatase E (chondrodysplasia punctata 1) |
ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
ATXN2L | ataxin 2-like |
BCAS3 | breast carcinoma amplified sequence 3 |
BLZF1 | basic leucine zipper nuclear factor 1 |
BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
CASZ1 | castor zinc finger 1 |
CCL7 | chemokine (C-C motif) ligand 7 |
CD47 | CD47 molecule |
CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
CHAT | choline O-acetyltransferase |
CNTNAP2 | contactin associated protein-like 2 |
COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
CXCL3 | chemokine (C-X-C motif) ligand 3 |
DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DMP1 | dentin matrix acidic phosphoprotein 1 |
ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
EXPH5 | exophilin 5 |
EZR | ezrin |
F12 | coagulation factor XII (Hageman factor) |
FADS3 | fatty acid desaturase 3 |
FGL1 | fibrinogen-like 1 |
FRMPD1 | FERM and PDZ domain containing 1 |
FXYD2 | FXYD domain containing ion transport regulator 2 |
GADD45G | growth arrest and DNA-damage-inducible, gamma |
GPR132 | G protein-coupled receptor 132 |
GPR15 | G protein-coupled receptor 15 |
GPR22 | G protein-coupled receptor 22 |
GRSF1 | G-rich RNA sequence binding factor 1 |
HIST1H4E | histone cluster 1, H4e |
IKZF4 | IKAROS family zinc finger 4 (Eos) |
IL3RA | interleukin 3 receptor, alpha (low affinity) |
IRF4 | interferon regulatory factor 4 |
KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
LAMC2 | laminin, gamma 2 |
LEF1 | lymphoid enhancer-binding factor 1 |
LHFPL2 | lipoma HMGIC fusion partner-like 2 |
LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
LYRM9 | LYR motif containing 9 |
MAGEA5 | melanoma antigen family A5 |
MAL | mal, T-cell differentiation protein |
MAP4 | microtubule-associated protein 4 |
MAP6D1 | MAP6 domain containing 1 |
MLN | motilin |
MPPE1 | metallophosphoesterase 1 |
MXD1 | MAX dimerization protein 1 |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
NTNG1 | netrin G1 |
OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
PALLD | palladin, cytoskeletal associated protein |
PCDH11Y | protocadherin 11 Y-linked |
PDE4DIP | phosphodiesterase 4D interacting protein |
PDGFB | platelet-derived growth factor beta polypeptide |
PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
PGK1 | phosphoglycerate kinase 1 |
PLAC1 | placenta-specific 1 |
PRKCA | protein kinase C, alpha |
PTCRA | pre T-cell antigen receptor alpha |
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
QSER1 | glutamine and serine rich 1 |
RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
RPLP2 | ribosomal protein, large, P2 |
RSU1 | Ras suppressor protein 1 |
RTEL1 | regulator of telomere elongation helicase 1 |
SCAND2P | SCAN domain containing 2 pseudogene |
SCHIP1 | schwannomin interacting protein 1 |
SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
SPRR2B | small proline-rich protein 2B |
SRPK2 | SRSF protein kinase 2 |
SRR | serine racemase |
STK38 | serine/threonine kinase 38 |
SYT2 | synaptotagmin II |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TMEM30B | transmembrane protein 30B |
TNP2 | transition protein 2 (during histone to protamine replacement) |
TTLL3 | tubulin tyrosine ligase-like family member 3 |
URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
WSCD1 | WSC domain containing 1 |
YIPF2 | Yip1 domain family, member 2 |
ZBTB18 | zinc finger and BTB domain containing 18 |
ZC3H7B | zinc finger CCCH-type containing 7B |
ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
Symbol | Name |
---|---|
ACOX2 | acyl-CoA oxidase 2, branched chain |
AKTIP | AKT interacting protein |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
BRMS1 | breast cancer metastasis suppressor 1 |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
CAMK4 | calcium/calmodulin-dependent protein kinase IV |
CD3D | CD3d molecule, delta (CD3-TCR complex) |
CD70 | CD70 molecule |
CHPF | chondroitin polymerizing factor |
CLSPN | claspin |
CORT | cortistatin |
CSF3R | colony stimulating factor 3 receptor (granulocyte) |
CTAGE9 | CTAGE family, member 9 |
CTSV | cathepsin V |
DCAF13 | DDB1 and CUL4 associated factor 13 |
DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
DFNA5 | deafness, autosomal dominant 5 |
DGKG | diacylglycerol kinase, gamma 90kDa |
DNMBP | dynamin binding protein |
FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
FGF22 | fibroblast growth factor 22 |
FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
GPR19 | G protein-coupled receptor 19 |
GRAMD1B | GRAM domain containing 1B |
GSTA4 | glutathione S-transferase alpha 4 |
HIRA | histone cell cycle regulator |
HIST1H1B | histone cluster 1, H1b |
HIST1H3G | histone cluster 1, H3g |
HRAS | Harvey rat sarcoma viral oncogene homolog |
HYAL2 | hyaluronoglucosaminidase 2 |
IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
IGLV1-44 | immunoglobulin lambda variable 1-44 |
IPO4 | importin 4 |
JAM2 | junctional adhesion molecule 2 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KDM5C | lysine (K)-specific demethylase 5C |
KLHL26 | kelch-like family member 26 |
KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
MAGEB2 | melanoma antigen family B2 |
MAP3K11 | mitogen-activated protein kinase kinase kinase 11 |
MAPK3 | mitogen-activated protein kinase 3 |
MB | myoglobin |
MFSD6 | major facilitator superfamily domain containing 6 |
MLPH | melanophilin |
MTMR12 | myotubularin related protein 12 |
NAG18 | NAG18 mRNA |
NBEAL2 | neurobeachin-like 2 |
NFS1 | NFS1 cysteine desulfurase |
NPDC1 | neural proliferation, differentiation and control, 1 |
OXTR | oxytocin receptor |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PDE12 | phosphodiesterase 12 |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
POR | P450 (cytochrome) oxidoreductase |
PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
PRDM1 | PR domain containing 1, with ZNF domain |
PYGB | phosphorylase, glycogen; brain |
RNF31 | ring finger protein 31 |
RPL23AP7 | ribosomal protein L23a pseudogene 7 |
RPP25 | ribonuclease P/MRP 25kDa subunit |
RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
RRP1 | ribosomal RNA processing 1 |
SAP30L | SAP30-like |
SCN10A | sodium channel, voltage gated, type X alpha subunit |
SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
SFT2D2 | SFT2 domain containing 2 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SMR3A | submaxillary gland androgen regulated protein 3A |
SP140 | SP140 nuclear body protein |
SPAG1 | sperm associated antigen 1 |
SPON2 | spondin 2, extracellular matrix protein |
ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
STBD1 | starch binding domain 1 |
SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
TESK1 | testis-specific kinase 1 |
TMEM120B | transmembrane protein 120B |
TMEM134 | transmembrane protein 134 |
TRABD | TraB domain containing |
TRAF1 | TNF receptor-associated factor 1 |
TUBB2A | tubulin, beta 2A class IIa |
WDR91 | WD repeat domain 91 |
YOD1 | YOD1 deubiquitinase |
ZNF215 | zinc finger protein 215 |
ZNF286A | zinc finger protein 286A |
ZNF580 | zinc finger protein 580 |
ZNF623 | zinc finger protein 623 |
ZNF862 | zinc finger protein 862 |