Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the nipecotic acid-5999 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AAMDC | adipogenesis associated, Mth938 domain containing |
ADCY2 | adenylate cyclase 2 (brain) |
ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
AMPH | amphiphysin |
AOX1 | aldehyde oxidase 1 |
BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
C11ORF1 | chromosome 11 open reading frame 1 |
C21ORF2 | chromosome 21 open reading frame 2 |
CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
CASR | calcium-sensing receptor |
CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
CD22 | CD22 molecule |
CD3D | CD3d molecule, delta (CD3-TCR complex) |
CD53 | CD53 molecule |
CD58 | CD58 molecule |
CDH10 | cadherin 10, type 2 (T2-cadherin) |
CDRT1 | CMT1A duplicated region transcript 1 |
CEP164 | centrosomal protein 164kDa |
CNPY4 | canopy FGF signaling regulator 4 |
COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
CRMP1 | collapsin response mediator protein 1 |
CXORF21 | chromosome X open reading frame 21 |
DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
DMBT1 | deleted in malignant brain tumors 1 |
DOCK9 | dedicator of cytokinesis 9 |
DOK4 | docking protein 4 |
DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
EDNRA | endothelin receptor type A |
EGFR | epidermal growth factor receptor |
ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
EPHB2 | EPH receptor B2 |
EXOSC1 | exosome component 1 |
FN1 | fibronectin 1 |
GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
GPATCH4 | G patch domain containing 4 |
GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
HBEGF | heparin-binding EGF-like growth factor |
HBS1L | HBS1-like translational GTPase |
HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
HOXC5 | homeobox C5 |
IAPP | islet amyloid polypeptide |
ING2 | inhibitor of growth family, member 2 |
IRS2 | insulin receptor substrate 2 |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
KCNIP1 | Kv channel interacting protein 1 |
KCNIP2 | Kv channel interacting protein 2 |
LGALS2 | lectin, galactoside-binding, soluble, 2 |
LOC644450 | uncharacterized LOC644450 |
MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
MLXIP | MLX interacting protein |
MST1L | macrophage stimulating 1-like |
MX1 | MX dynamin-like GTPase 1 |
MYOZ1 | myozenin 1 |
N4BP3 | NEDD4 binding protein 3 |
NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NMT2 | N-myristoyltransferase 2 |
NRF1 | nuclear respiratory factor 1 |
PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
PDLIM5 | PDZ and LIM domain 5 |
PEX3 | peroxisomal biogenesis factor 3 |
PLAU | plasminogen activator, urokinase |
PML | promyelocytic leukemia |
PPP1R3A | protein phosphatase 1, regulatory subunit 3A |
PRDM2 | PR domain containing 2, with ZNF domain |
PRKCI | protein kinase C, iota |
PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
RPL35A | ribosomal protein L35a |
SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
SFRP5 | secreted frizzled-related protein 5 |
SH3BP2 | SH3-domain binding protein 2 |
SIPA1 | signal-induced proliferation-associated 1 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
SOCS7 | suppressor of cytokine signaling 7 |
SSTR2 | somatostatin receptor 2 |
STOM | stomatin |
STS | steroid sulfatase (microsomal), isozyme S |
SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
TBXA2R | thromboxane A2 receptor |
TLR8 | toll-like receptor 8 |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
TRIM10 | tripartite motif containing 10 |
TTC38 | tetratricopeptide repeat domain 38 |
UBE3A | ubiquitin protein ligase E3A |
UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
VPS9D1 | VPS9 domain containing 1 |
WLS | wntless Wnt ligand secretion mediator |
ZER1 | zyg-11 related, cell cycle regulator |
ZNF507 | zinc finger protein 507 |
Symbol | Name |
---|---|
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ACSL4 | acyl-CoA synthetase long-chain family member 4 |
AMH | anti-Mullerian hormone |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
ARRB1 | arrestin, beta 1 |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
ATP7B | ATPase, Cu++ transporting, beta polypeptide |
BCAS1 | breast carcinoma amplified sequence 1 |
BPGM | 2,3-bisphosphoglycerate mutase |
C14ORF93 | chromosome 14 open reading frame 93 |
C17ORF70 | chromosome 17 open reading frame 70 |
C5AR2 | complement component 5a receptor 2 |
CBX8 | chromobox homolog 8 |
CCDC25 | coiled-coil domain containing 25 |
CCDC9 | coiled-coil domain containing 9 |
CD82 | CD82 molecule |
CDON | cell adhesion associated, oncogene regulated |
CFD | complement factor D (adipsin) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHRM3 | cholinergic receptor, muscarinic 3 |
CIC | capicua transcriptional repressor |
CIDEB | cell death-inducing DFFA-like effector b |
CINP | cyclin-dependent kinase 2 interacting protein |
CNN2 | calponin 2 |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
EFNA3 | ephrin-A3 |
FAM118A | family with sequence similarity 118, member A |
FBXO22 | F-box protein 22 |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
HINFP | histone H4 transcription factor |
HIRA | histone cell cycle regulator |
IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
ISG15 | ISG15 ubiquitin-like modifier |
ITPKB | inositol-trisphosphate 3-kinase B |
JMJD4 | jumonji domain containing 4 |
KIAA0319L | KIAA0319-like |
KIF16B | kinesin family member 16B |
KLF11 | Kruppel-like factor 11 |
LMNB1 | lamin B1 |
LRP5L | low density lipoprotein receptor-related protein 5-like |
LRRC23 | leucine rich repeat containing 23 |
LRRC37A2 | leucine rich repeat containing 37, member A2 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
MAN2C1 | mannosidase, alpha, class 2C, member 1 |
MANBA | mannosidase, beta A, lysosomal |
MAP1S | microtubule-associated protein 1S |
MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
MSL3 | male-specific lethal 3 homolog (Drosophila) |
MTERF1 | mitochondrial transcription termination factor 1 |
NDE1 | nudE neurodevelopment protein 1 |
NPFFR1 | neuropeptide FF receptor 1 |
NUPL2 | nucleoporin like 2 |
OSMR | oncostatin M receptor |
OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
PCDHA5 | protocadherin alpha 5 |
PDE8B | phosphodiesterase 8B |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
POLI | polymerase (DNA directed) iota |
PRMT7 | protein arginine methyltransferase 7 |
PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
RBL1 | retinoblastoma-like 1 |
RNF31 | ring finger protein 31 |
RPGR | retinitis pigmentosa GTPase regulator |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
SLC35F5 | solute carrier family 35, member F5 |
SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SND1-IT1 | SND1 intronic transcript 1 |
SPRYD7 | SPRY domain containing 7 |
TBC1D17 | TBC1 domain family, member 17 |
THBS3 | thrombospondin 3 |
TMEM121 | transmembrane protein 121 |
TRAPPC13 | trafficking protein particle complex 13 |
TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
TTBK2 | tau tubulin kinase 2 |
TTC30A | tetratricopeptide repeat domain 30A |
TUBA3C | tubulin, alpha 3c |
ULBP2 | UL16 binding protein 2 |
UNC119 | unc-119 homolog (C. elegans) |
USP20 | ubiquitin specific peptidase 20 |
XK | X-linked Kx blood group |
ZNF134 | zinc finger protein 134 |
ZNF136 | zinc finger protein 136 |
ZNF205 | zinc finger protein 205 |
ZNF227 | zinc finger protein 227 |
ZNF329 | zinc finger protein 329 |
ZNF365 | zinc finger protein 365 |
ZNF606 | zinc finger protein 606 |
ZNF778 | zinc finger protein 778 |
ZNF862 | zinc finger protein 862 |