nipecotic acid-7296 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the nipecotic acid-7296 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP35 Rho GTPase activating protein 35
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
AVL9 AVL9 homolog (S. cerevisiase)
BATF basic leucine zipper transcription factor, ATF-like
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C11ORF63 chromosome 11 open reading frame 63
C14ORF79 chromosome 14 open reading frame 79
C14ORF93 chromosome 14 open reading frame 93
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCSER2 coiled-coil serine-rich protein 2
CD33 CD33 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD58 CD58 molecule
CHD7 chromodomain helicase DNA binding protein 7
CHN2 chimerin 2
CLCN6 chloride channel, voltage-sensitive 6
CLEC7A C-type lectin domain family 7, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
COL3A1 collagen, type III, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CSHL1 chorionic somatomammotropin hormone-like 1
DCLK2 doublecortin-like kinase 2
DOCK9 dedicator of cytokinesis 9
DRD2 dopamine receptor D2
DTX2 deltex 2, E3 ubiquitin ligase
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
ELOVL5 ELOVL fatty acid elongase 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC8 excision repair cross-complementation group 8
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FAM174B family with sequence similarity 174, member B
FCMR Fc fragment of IgM receptor
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPER1 G protein-coupled estrogen receptor 1
GRM4 glutamate receptor, metabotropic 4
GSK3A glycogen synthase kinase 3 alpha
HDAC9 histone deacetylase 9
HIST1H1E histone cluster 1, H1e
HIST1H2AB histone cluster 1, H2ab
HSDL2 hydroxysteroid dehydrogenase like 2
IFNA14 interferon, alpha 14
JRK Jrk homolog (mouse)
JUNB jun B proto-oncogene
KIAA0040 KIAA0040
KIAA1109 KIAA1109
LIG4 ligase IV, DNA, ATP-dependent
LRP3 low density lipoprotein receptor-related protein 3
LY96 lymphocyte antigen 96
MARS methionyl-tRNA synthetase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
MUC7 mucin 7, secreted
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NINJ1 ninjurin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PAQR6 progestin and adipoQ receptor family member VI
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB26 RAB26, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
REST RE1-silencing transcription factor
RHBDD3 rhomboid domain containing 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRAGB Ras-related GTP binding B
SEC24D SEC24 family member D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIDT2 SID1 transmembrane family, member 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPATA2L spermatogenesis associated 2-like
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SSX3 synovial sarcoma, X breakpoint 3
STAC SH3 and cysteine rich domain
STIM1 stromal interaction molecule 1
SUN1 Sad1 and UNC84 domain containing 1
TMCC1 transmembrane and coiled-coil domain family 1
TMEM63A transmembrane protein 63A
TNIK TRAF2 and NCK interacting kinase
TRAF2 TNF receptor-associated factor 2
TRIL TLR4 interactor with leucine-rich repeats
TTC12 tetratricopeptide repeat domain 12
UEVLD UEV and lactate/malate dehyrogenase domains
XYLB xylulokinase homolog (H. influenzae)
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710
ZNF749 zinc finger protein 749
ZNF768 zinc finger protein 768
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AP4M1 adaptor-related protein complex 4, mu 1 subunit
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BTBD2 BTB (POZ) domain containing 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CCP110 centriolar coiled coil protein 110kDa
CEP112 centrosomal protein 112kDa
CLDN14 claudin 14
CLEC2B C-type lectin domain family 2, member B
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCL2 chemokine (C-X-C motif) ligand 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DLK1 delta-like 1 homolog (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DNMBP dynamin binding protein
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FADS2 fatty acid desaturase 2
FANCF Fanconi anemia, complementation group F
FKBP1B FK506 binding protein 1B, 12.6 kDa
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2L G patch domain containing 2-like
HCFC2 host cell factor C2
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H2AM histone cluster 1, H2am
HLX H2.0-like homeobox
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HYI hydroxypyruvate isomerase (putative)
IL17RA interleukin 17 receptor A
IL7R interleukin 7 receptor
INF2 inverted formin, FH2 and WH2 domain containing
KCTD20 potassium channel tetramerization domain containing 20
KIAA0319L KIAA0319-like
KRT4 keratin 4, type II
LIG1 ligase I, DNA, ATP-dependent
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK12 mitogen-activated protein kinase 12
MB myoglobin
METTL22 methyltransferase like 22
MFGE8 milk fat globule-EGF factor 8 protein
MFSD11 major facilitator superfamily domain containing 11
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMP13 matrix metallopeptidase 13
MXD3 MAX dimerization protein 3
MXRA8 matrix-remodelling associated 8
NABP2 nucleic acid binding protein 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NLRX1 NLR family member X1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNRC1 proline-rich nuclear receptor coactivator 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRPF38B pre-mRNA processing factor 38B
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM47 RNA binding motif protein 47
RBM4B RNA binding motif protein 4B
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
SCML2 sex comb on midleg-like 2 (Drosophila)
SESN1 sestrin 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
STAP2 signal transducing adaptor family member 2
STAR steroidogenic acute regulatory protein
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TJP2 tight junction protein 2
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USP6NL USP6 N-terminal like
VEZT vezatin, adherens junctions transmembrane protein
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZFP69B ZFP69 zinc finger protein B
ZNF230 zinc finger protein 230
ZNF280D zinc finger protein 280D
ZNF816 zinc finger protein 816