niridazole-2440 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the niridazole-2440 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ALDOB aldolase B, fructose-bisphosphate
ALG12 ALG12, alpha-1,6-mannosyltransferase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AURKA aurora kinase A
C20ORF27 chromosome 20 open reading frame 27
CA1 carbonic anhydrase I
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC85B coiled-coil domain containing 85B
CCL22 chemokine (C-C motif) ligand 22
CDC14B cell division cycle 14B
CEP41 centrosomal protein 41kDa
CRTC1 CREB regulated transcription coactivator 1
DFNB31 deafness, autosomal recessive 31
DUSP1 dual specificity phosphatase 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
EWSR1 EWS RNA-binding protein 1
FCMR Fc fragment of IgM receptor
FGFBP1 fibroblast growth factor binding protein 1
FGFR1 fibroblast growth factor receptor 1
FOXO1 forkhead box O1
FXYD2 FXYD domain containing ion transport regulator 2
GAB1 GRB2-associated binding protein 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GP2 glycoprotein 2 (zymogen granule membrane)
GSK3A glycogen synthase kinase 3 alpha
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUK1 guanylate kinase 1
HBE1 hemoglobin, epsilon 1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HYI hydroxypyruvate isomerase (putative)
IFT122 intraflagellar transport 122
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING2 inhibitor of growth family, member 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LEFTY2 left-right determination factor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC01558 long intergenic non-protein coding RNA 1558
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
METTL16 methyltransferase like 16
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCLN nicalin
NEBL nebulette
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAX5 paired box 5
PBX2 pre-B-cell leukemia homeobox 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PGAP1 post-GPI attachment to proteins 1
PKNOX1 PBX/knotted 1 homeobox 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
RAB13 RAB13, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RELN reelin
RHOBTB3 Rho-related BTB domain containing 3
RNF39 ring finger protein 39
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SALL2 spalt-like transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SGCE sarcoglycan, epsilon
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC17A2 solute carrier family 17, member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMAD3 SMAD family member 3
SP1 Sp1 transcription factor
SRSF7 serine/arginine-rich splicing factor 7
SS18 synovial sarcoma translocation, chromosome 18
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNDIG1 synapse differentiation inducing 1
TCP11L1 t-complex 11, testis-specific-like 1
TEX40 testis expressed 40
TFG TRK-fused gene
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THAP10 THAP domain containing 10
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TPMT thiopurine S-methyltransferase
TRD T cell receptor delta locus
TRGV5 T cell receptor gamma variable 5
TRIM25 tripartite motif containing 25
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YTHDC2 YTH domain containing 2
ZC3H13 zinc finger CCCH-type containing 13
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
ANXA2P2 annexin A2 pseudogene 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C21ORF91 chromosome 21 open reading frame 91
C5ORF45 chromosome 5 open reading frame 45
C9ORF9 chromosome 9 open reading frame 9
CABIN1 calcineurin binding protein 1
CAMKMT calmodulin-lysine N-methyltransferase
CCDC176 coiled-coil domain containing 176
CCDC9 coiled-coil domain containing 9
CDKL3 cyclin-dependent kinase-like 3
CLIP2 CAP-GLY domain containing linker protein 2
COL9A2 collagen, type IX, alpha 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRY2 cryptochrome circadian clock 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK4 dedicator of cytokinesis 4
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ERCC4 excision repair cross-complementation group 4
FAM102A family with sequence similarity 102, member A
FBXL6 F-box and leucine-rich repeat protein 6
FGF23 fibroblast growth factor 23
FMNL1 formin-like 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GIPC1 GIPC PDZ domain containing family, member 1
GJA8 gap junction protein, alpha 8, 50kDa
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPNMB glycoprotein (transmembrane) nmb
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HOPX HOP homeobox
IL1R2 interleukin 1 receptor, type II
IL2 interleukin 2
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
IQCG IQ motif containing G
IZUMO4 IZUMO family member 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLHL36 kelch-like family member 36
LIMD2 LIM domain containing 2
LIN7B lin-7 homolog B (C. elegans)
LINS lines homolog (Drosophila)
LTBP3 latent transforming growth factor beta binding protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK10 mitogen-activated protein kinase 10
MYBPH myosin binding protein H
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PADI1 peptidyl arginine deiminase, type I
PDZD7 PDZ domain containing 7
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PNOC prepronociceptin
POLH polymerase (DNA directed), eta
PRICKLE3 prickle homolog 3 (Drosophila)
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
QPCTL glutaminyl-peptide cyclotransferase-like
RAB17 RAB17, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RCAN3 RCAN family member 3
REC8 REC8 meiotic recombination protein
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RLF rearranged L-myc fusion
SCAMP4 secretory carrier membrane protein 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAT5A signal transducer and activator of transcription 5A
STBD1 starch binding domain 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TIMP2 TIMP metallopeptidase inhibitor 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TK1 thymidine kinase 1, soluble
TMEM53 transmembrane protein 53
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN2 tetraspanin 2
UBXN6 UBX domain protein 6
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZNF137P zinc finger protein 137, pseudogene
ZNF324 zinc finger protein 324
ZNF76 zinc finger protein 76