| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the niridazole-2440 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| AURKA | aurora kinase A |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CA1 | carbonic anhydrase I |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC85B | coiled-coil domain containing 85B |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CDC14B | cell division cycle 14B |
| CEP41 | centrosomal protein 41kDa |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DUSP1 | dual specificity phosphatase 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EWSR1 | EWS RNA-binding protein 1 |
| FCMR | Fc fragment of IgM receptor |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOXO1 | forkhead box O1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GAB1 | GRB2-associated binding protein 1 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUK1 | guanylate kinase 1 |
| HBE1 | hemoglobin, epsilon 1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| IFT122 | intraflagellar transport 122 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ING2 | inhibitor of growth family, member 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LEFTY2 | left-right determination factor 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC01558 | long intergenic non-protein coding RNA 1558 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTD1 | mbt domain containing 1 |
| MCL1 | myeloid cell leukemia 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| METTL16 | methyltransferase like 16 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCLN | nicalin |
| NEBL | nebulette |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAX5 | paired box 5 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PGAP1 | post-GPI attachment to proteins 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| RAB13 | RAB13, member RAS oncogene family |
| RAB40A | RAB40A, member RAS oncogene family |
| RELN | reelin |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNF39 | ring finger protein 39 |
| RUNX1 | runt-related transcription factor 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SALL2 | spalt-like transcription factor 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGCE | sarcoglycan, epsilon |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SMAD3 | SMAD family member 3 |
| SP1 | Sp1 transcription factor |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX40 | testis expressed 40 |
| TFG | TRK-fused gene |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THAP10 | THAP domain containing 10 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TRGV5 | T cell receptor gamma variable 5 |
| TRIM25 | tripartite motif containing 25 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| YTHDC2 | YTH domain containing 2 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| AGO4 | argonaute RISC catalytic component 4 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CABIN1 | calcineurin binding protein 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC9 | coiled-coil domain containing 9 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRY2 | cryptochrome circadian clock 2 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOCK4 | dedicator of cytokinesis 4 |
| EFNA3 | ephrin-A3 |
| EMID1 | EMI domain containing 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM102A | family with sequence similarity 102, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FGF23 | fibroblast growth factor 23 |
| FMNL1 | formin-like 1 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPNMB | glycoprotein (transmembrane) nmb |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOPX | HOP homeobox |
| IL1R2 | interleukin 1 receptor, type II |
| IL2 | interleukin 2 |
| IL4R | interleukin 4 receptor |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IQCG | IQ motif containing G |
| IZUMO4 | IZUMO family member 4 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KLHL36 | kelch-like family member 36 |
| LIMD2 | LIM domain containing 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINS | lines homolog (Drosophila) |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MYBPH | myosin binding protein H |
| NDE1 | nudE neurodevelopment protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDZD7 | PDZ domain containing 7 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PNOC | prepronociceptin |
| POLH | polymerase (DNA directed), eta |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB17 | RAB17, member RAS oncogene family |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RCAN3 | RCAN family member 3 |
| REC8 | REC8 meiotic recombination protein |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RLF | rearranged L-myc fusion |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STAT5A | signal transducer and activator of transcription 5A |
| STBD1 | starch binding domain 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBX19 | T-box 19 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TK1 | thymidine kinase 1, soluble |
| TMEM53 | transmembrane protein 53 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN2 | tetraspanin 2 |
| UBXN6 | UBX domain protein 6 |
| USP20 | ubiquitin specific peptidase 20 |
| VASH1 | vasohibin 1 |
| WDR62 | WD repeat domain 62 |
| XYLT2 | xylosyltransferase II |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF324 | zinc finger protein 324 |
| ZNF76 | zinc finger protein 76 |