niridazole-5682 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the niridazole-5682 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACOT11 acyl-CoA thioesterase 11
ADAM12 ADAM metallopeptidase domain 12
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C1ORF61 chromosome 1 open reading frame 61
CA9 carbonic anhydrase IX
CD34 CD34 molecule
CD58 CD58 molecule
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CLCA2 chloride channel accessory 2
CNPY4 canopy FGF signaling regulator 4
COL4A2 collagen, type IV, alpha 2
COL6A1 collagen, type VI, alpha 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DEFA4 defensin, alpha 4, corticostatin
DFNB31 deafness, autosomal recessive 31
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DPY19L1P1 DPY19L1 pseudogene 1
DYSF dysferlin
E2F4 E2F transcription factor 4, p107/p130-binding
EDA ectodysplasin A
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERC2-IT1 ERC2 intronic transcript 1
F13A1 coagulation factor XIII, A1 polypeptide
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FRMD8 FERM domain containing 8
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GK2 glycerol kinase 2
GLIPR1 GLI pathogenesis-related 1
GOLGA8A golgin A8 family, member A
GPA33 glycoprotein A33 (transmembrane)
GPATCH3 G patch domain containing 3
GPR15 G protein-coupled receptor 15
GPR20 G protein-coupled receptor 20
HAB1 B1 for mucin
HLA-J major histocompatibility complex, class I, J (pseudogene)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXC5 homeobox C5
HRASLS2 HRAS-like suppressor 2
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IGLL1 immunoglobulin lambda-like polypeptide 1
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD17 potassium channel tetramerization domain containing 17
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT83 keratin 83, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LPAR4 lysophosphatidic acid receptor 4
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL7A methyltransferase like 7A
MR1 major histocompatibility complex, class I-related
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NDRG2 NDRG family member 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEUROD4 neuronal differentiation 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OR7A5 olfactory receptor, family 7, subfamily A, member 5
PDE10A phosphodiesterase 10A
PHF20 PHD finger protein 20
PKNOX1 PBX/knotted 1 homeobox 1
PLSCR2 phospholipid scramblase 2
POU2F2 POU class 2 homeobox 2
PRB3 proline-rich protein BstNI subfamily 3
PRDM1 PR domain containing 1, with ZNF domain
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RND1 Rho family GTPase 1
RUFY3 RUN and FYVE domain containing 3
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3GL3 SH3-domain GRB2-like 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SPAG6 sperm associated antigen 6
SSX3 synovial sarcoma, X breakpoint 3
STOML1 stomatin (EPB72)-like 1
SYN3 synapsin III
TBC1D2B TBC1 domain family, member 2B
THBS3 thrombospondin 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNK2 tyrosine kinase, non-receptor, 2
TRAT1 T cell receptor associated transmembrane adaptor 1
TRD T cell receptor delta locus
TUBA4B tubulin, alpha 4b
VIPR1 vasoactive intestinal peptide receptor 1
ZNF711 zinc finger protein 711

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AFAP1 actin filament associated protein 1
ALS2CL ALS2 C-terminal like
ANKRD36 ankyrin repeat domain 36
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX2 armadillo repeat containing, X-linked 2
ATAD5 ATPase family, AAA domain containing 5
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCAS1 breast carcinoma amplified sequence 1
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF80 chromosome 11 open reading frame 80
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC186 coiled-coil domain containing 186
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CFAP44 cilia and flagella associated protein 44
CFD complement factor D (adipsin)
CHML choroideremia-like (Rab escort protein 2)
CINP cyclin-dependent kinase 2 interacting protein
CRABP1 cellular retinoic acid binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CXORF21 chromosome X open reading frame 21
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DRD1 dopamine receptor D1
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
FGF23 fibroblast growth factor 23
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALT galactose-1-phosphate uridylyltransferase
GMIP GEM interacting protein
GPR87 G protein-coupled receptor 87
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HOXD11 homeobox D11
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI27 interferon, alpha-inducible protein 27
ISG15 ISG15 ubiquitin-like modifier
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KLF2 Kruppel-like factor 2
LHX1 LIM homeobox 1
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MMP9 matrix metallopeptidase 9
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYL5 myosin, light chain 5, regulatory
NEB nebulin
OCA2 oculocutaneous albinism II
ODF2 outer dense fiber of sperm tails 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGR progesterone receptor
PLA2G15 phospholipase A2, group XV
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNPLA6 patatin-like phospholipase domain containing 6
PRPH peripherin
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB3D RAB3D, member RAS oncogene family
RCAN3 RCAN family member 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
SCAI suppressor of cancer cell invasion
SCRN3 secernin 3
SDC3 syndecan 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH2B3 SH2B adaptor protein 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STARD3 StAR-related lipid transfer (START) domain containing 3
SYBU syntabulin (syntaxin-interacting)
TBC1D17 TBC1 domain family, member 17
TBR1 T-box, brain, 1
TGFBR3 transforming growth factor, beta receptor III
TIGD6 tigger transposable element derived 6
TMEM19 transmembrane protein 19
TNRC6B trinucleotide repeat containing 6B
TREM1 triggering receptor expressed on myeloid cells 1
TRIM5 tripartite motif containing 5
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF10 zinc finger protein 10
ZNF134 zinc finger protein 134
ZNF280D zinc finger protein 280D
ZNF428 zinc finger protein 428
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747
ZNRD1-AS1 ZNRD1 antisense RNA 1