| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the nisoxetine-3117 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BNC2 | basonuclin 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CAPN3 | calpain 3, (p94) |
| CCDC181 | coiled-coil domain containing 181 |
| CD200 | CD200 molecule |
| CD47 | CD47 molecule |
| CD6 | CD6 molecule |
| CDC14A | cell division cycle 14A |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDON | cell adhesion associated, oncogene regulated |
| CFAP70 | cilia and flagella associated protein 70 |
| CHN2 | chimerin 2 |
| CLEC3B | C-type lectin domain family 3, member B |
| COL5A1 | collagen, type V, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CREM | cAMP responsive element modulator |
| CRP | C-reactive protein, pentraxin-related |
| CST1 | cystatin SN |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DOK3 | docking protein 3 |
| ECE2 | endothelin converting enzyme 2 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ENDOD1 | endonuclease domain containing 1 |
| F12 | coagulation factor XII (Hageman factor) |
| FADS3 | fatty acid desaturase 3 |
| FAM76A | family with sequence similarity 76, member A |
| FGFR2 | fibroblast growth factor receptor 2 |
| FOSL1 | FOS-like antigen 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPM6A | glycoprotein M6A |
| GPR153 | G protein-coupled receptor 153 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSPT1 | G1 to S phase transition 1 |
| HDAC11 | histone deacetylase 11 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| ICAM1 | intercellular adhesion molecule 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IZUMO4 | IZUMO family member 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLK11 | kallikrein-related peptidase 11 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP1A | microtubule-associated protein 1A |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MOXD1 | monooxygenase, DBH-like 1 |
| MYOZ3 | myozenin 3 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| OCM2 | oncomodulin 2 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PAX8 | paired box 8 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIWIL2 | piwi-like RNA-mediated gene silencing 2 |
| POU6F1 | POU class 6 homeobox 1 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTCRA | pre T-cell antigen receptor alpha |
| PXN | paxillin |
| REC8 | REC8 meiotic recombination protein |
| RGS12 | regulator of G-protein signaling 12 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL3L | ribosomal protein L3-like |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOCS2 | suppressor of cytokine signaling 2 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THBS1 | thrombospondin 1 |
| TMOD1 | tropomodulin 1 |
| TPMT | thiopurine S-methyltransferase |
| TRIM15 | tripartite motif containing 15 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TUBB1 | tubulin, beta 1 class VI |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| VSX1 | visual system homeobox 1 |
| WWC1 | WW and C2 domain containing 1 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF276 | zinc finger protein 276 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AKTIP | AKT interacting protein |
| ANAPC2 | anaphase promoting complex subunit 2 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP13A1 | ATPase type 13A1 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CBX4 | chromobox homolog 4 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDCP1 | CUB domain containing protein 1 |
| CHPF | chondroitin polymerizing factor |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CORO7 | coronin 7 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) |
| CTSV | cathepsin V |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EXOC6B | exocyst complex component 6B |
| FAM127A | family with sequence similarity 127, member A |
| FBRS | fibrosin |
| FGF9 | fibroblast growth factor 9 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GAA | glucosidase, alpha; acid |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSS | glutathione synthetase |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL28 | kelch-like family member 28 |
| LOC157562 | uncharacterized LOC157562 |
| LOC729164 | hCG1732469 |
| MAGEF1 | melanoma antigen family F1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MRPL28 | mitochondrial ribosomal protein L28 |
| MTMR12 | myotubularin related protein 12 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1E | myosin IE |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NXPH4 | neurexophilin 4 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RHOB | ras homolog family member B |
| RIN1 | Ras and Rab interactor 1 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SIRT6 | sirtuin 6 |
| SKI | SKI proto-oncogene |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST7L | suppression of tumorigenicity 7 like |
| STEAP3 | STEAP family member 3, metalloreductase |
| STX11 | syntaxin 11 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SURF2 | surfeit 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBL3 | transducin (beta)-like 3 |
| TEC | tec protein tyrosine kinase |
| TERT | telomerase reverse transcriptase |
| TESK1 | testis-specific kinase 1 |
| TMEM180 | transmembrane protein 180 |
| TMEM212 | transmembrane protein 212 |
| TMEM53 | transmembrane protein 53 |
| TRABD | TraB domain containing |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT61A | tRNA methyltransferase 61A |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| ULBP2 | UL16 binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF493 | zinc finger protein 493 |
| ZNF557 | zinc finger protein 557 |
