| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nisoxetine-5091 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACE2 | angiotensin I converting enzyme 2 |
| ACTN1 | actinin, alpha 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| AIM1L | absent in melanoma 1-like |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBS | cystathionine-beta-synthase |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDN | dendrin |
| DENND3 | DENN/MADD domain containing 3 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ETV6 | ets variant 6 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FGF5 | fibroblast growth factor 5 |
| FOXN2 | forkhead box N2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLE1 | GLE1 RNA export mediator |
| GPM6B | glycoprotein M6B |
| GPR176 | G protein-coupled receptor 176 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GRIP2 | glutamate receptor interacting protein 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIC2 | hypermethylated in cancer 2 |
| IQCA1 | IQ motif containing with AAA domain 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLHL25 | kelch-like family member 25 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MAP4 | microtubule-associated protein 4 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MIIP | migration and invasion inhibitory protein |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NRXN3 | neurexin 3 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDLIM5 | PDZ and LIM domain 5 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLXND1 | plexin D1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PVR | poliovirus receptor |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF39 | ring finger protein 39 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUNX1 | runt-related transcription factor 1 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCN2A | sodium channel, voltage gated, type II alpha subunit |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SNRK | SNF related kinase |
| SP110 | SP110 nuclear body protein |
| SPTB | spectrin, beta, erythrocytic |
| STAB2 | stabilin 2 |
| STC2 | stanniocalcin 2 |
| TADA3 | transcriptional adaptor 3 |
| TLR2 | toll-like receptor 2 |
| TMC6 | transmembrane channel-like 6 |
| TMEM231 | transmembrane protein 231 |
| TMEM63A | transmembrane protein 63A |
| TNXB | tenascin XB |
| TRAC | T cell receptor alpha constant |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TUBA4B | tubulin, alpha 4b |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF154 | zinc finger protein 154 |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| BSPRY | B-box and SPRY domain containing |
| BTC | betacellulin |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP112 | centrosomal protein 112kDa |
| CLDN8 | claudin 8 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ETNK2 | ethanolamine kinase 2 |
| FAM222B | family with sequence similarity 222, member B |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOXA1 | forkhead box A1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GAS8 | growth arrest-specific 8 |
| GSR | glutathione reductase |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3F | histone cluster 1, H3f |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IFI44L | interferon-induced protein 44-like |
| IFNA2 | interferon, alpha 2 |
| IFT54 | intraflagellar transport 54 |
| IQCG | IQ motif containing G |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA1107 | KIAA1107 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC61 | leucine rich repeat containing 61 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEA6 | melanoma antigen family A6 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MATN3 | matrilin 3 |
| MOSPD3 | motile sperm domain containing 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDP | Norrie disease (pseudoglioma) |
| NDRG4 | NDRG family member 4 |
| NXPH4 | neurexophilin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PALMD | palmdelphin |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLD3 | phospholipase D family, member 3 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| QSER1 | glutamine and serine rich 1 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF31 | ring finger protein 31 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLN | sarcolipin |
| SNHG3 | small nucleolar RNA host gene 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TNRC6B | trinucleotide repeat containing 6B |
| TNS2 | tensin 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| USB1 | U6 snRNA biogenesis 1 |
| VGF | VGF nerve growth factor inducible |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF358 | zinc finger protein 358 |
| ZNF428 | zinc finger protein 428 |
| ZNF446 | zinc finger protein 446 |
| ZNF711 | zinc finger protein 711 |
| ZNF76 | zinc finger protein 76 |
