| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the nisoxetine-5516 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAMTSL4 | ADAMTS-like 4 |
| AHI1 | Abelson helper integration site 1 |
| AMELX | amelogenin, X-linked |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ASPN | asporin |
| BMP8B | bone morphogenetic protein 8b |
| BRS3 | bombesin-like receptor 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CES1 | carboxylesterase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CYP2A7P1 | cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 |
| DLL3 | delta-like 3 (Drosophila) |
| DUSP10 | dual specificity phosphatase 10 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EMC3 | ER membrane protein complex subunit 3 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPHA3 | EPH receptor A3 |
| EPHB2 | EPH receptor B2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBLN1 | fibulin 1 |
| FHL1 | four and a half LIM domains 1 |
| GATA4 | GATA binding protein 4 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPR15 | G protein-coupled receptor 15 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HLA-G | major histocompatibility complex, class I, G |
| HOXA9 | homeobox A9 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL1B | interleukin 1, beta |
| IL6ST | interleukin 6 signal transducer |
| INA | internexin neuronal intermediate filament protein, alpha |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT24 | keratin 24, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIMK2 | LIM domain kinase 2 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LYST | lysosomal trafficking regulator |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRAS | muscle RAS oncogene homolog |
| MX2 | MX dynamin-like GTPase 2 |
| MYO7B | myosin VIIB |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NLGN4X | neuroligin 4, X-linked |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PITX1 | paired-like homeodomain 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RAP2A | RAP2A, member of RAS oncogene family |
| RHOT2 | ras homolog family member T2 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPL10L | ribosomal protein L10-like |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC22A17 | solute carrier family 22, member 17 |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPRR1B | small proline-rich protein 1B |
| STRN3 | striatin, calmodulin binding protein 3 |
| STX1A | syntaxin 1A (brain) |
| SUGP1 | SURP and G patch domain containing 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFF2 | trefoil factor 2 |
| TFR2 | transferrin receptor 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| UBXN1 | UBX domain protein 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF134 | zinc finger protein 134 |
| ZNF510 | zinc finger protein 510 |
| ZNF747 | zinc finger protein 747 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| AFG3L2 | AFG3-like AAA ATPase 2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARMC7 | armadillo repeat containing 7 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN5 | calpain 5 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CENPT | centromere protein T |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CISH | cytokine inducible SH2-containing protein |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| ERF | Ets2 repressor factor |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FANCE | Fanconi anemia, complementation group E |
| FKBPL | FK506 binding protein like |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H1D | histone cluster 1, H1d |
| HOXD11 | homeobox D11 |
| HSPA1L | heat shock 70kDa protein 1-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LAMA5 | laminin, alpha 5 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LHX6 | LIM homeobox 6 |
| LMBR1L | limb development membrane protein 1-like |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MYL5 | myosin, light chain 5, regulatory |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDE1 | nudE neurodevelopment protein 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OCEL1 | occludin/ELL domain containing 1 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PGP | phosphoglycolate phosphatase |
| PLAC8 | placenta-specific 8 |
| PMCH | pro-melanin-concentrating hormone |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| REEP4 | receptor accessory protein 4 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RGS17 | regulator of G-protein signaling 17 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF122 | ring finger protein 122 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SP140L | SP140 nuclear body protein-like |
| SPIDR | scaffolding protein involved in DNA repair |
| STAG3 | stromal antigen 3 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TAGLN | transgelin |
| TKFC | triokinase/FMN cyclase |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPTE | transmembrane phosphatase with tensin homology |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN1 | tetraspanin 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USP18 | ubiquitin specific peptidase 18 |
| VAX2 | ventral anterior homeobox 2 |
| WDR62 | WD repeat domain 62 |
| XK | X-linked Kx blood group |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF480 | zinc finger protein 480 |
| ZNF492 | zinc finger protein 492 |
| ZNF696 | zinc finger protein 696 |
| ZNF770 | zinc finger protein 770 |
