| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the nisoxetine-6496 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACO2 | aconitase 2, mitochondrial |
| ACPP | acid phosphatase, prostate |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOC4 | apolipoprotein C-IV |
| BGN | biglycan |
| C10ORF95 | chromosome 10 open reading frame 95 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD14 | CD14 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CIB2 | calcium and integrin binding family member 2 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| DENND5B | DENN/MADD domain containing 5B |
| DLEC1 | deleted in lung and esophageal cancer 1 |
| DLG5 | discs, large homolog 5 (Drosophila) |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK4 | docking protein 4 |
| DSG3 | desmoglein 3 |
| DVL3 | dishevelled segment polarity protein 3 |
| EDNRA | endothelin receptor type A |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPHA1 | EPH receptor A1 |
| ETV5 | ets variant 5 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FABP7 | fatty acid binding protein 7, brain |
| FAM134B | family with sequence similarity 134, member B |
| FBLN1 | fibulin 1 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FPR1 | formyl peptide receptor 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GID4 | GID complex subunit 4 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GK | glycerol kinase |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HMHB1 | histocompatibility (minor) HB-1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HR | hair growth associated |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL11 | interleukin 11 |
| INO80B | INO80 complex subunit B |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIF25 | kinesin family member 25 |
| LAMA4 | laminin, alpha 4 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LOX | lysyl oxidase |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MTMR8 | myotubularin related protein 8 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MVK | mevalonate kinase |
| NEUROD1 | neuronal differentiation 1 |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| PARD3 | par-3 family cell polarity regulator |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PEG10 | paternally expressed 10 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RCAN1 | regulator of calcineurin 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SIRT4 | sirtuin 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SMAD3 | SMAD family member 3 |
| STK3 | serine/threonine kinase 3 |
| STX7 | syntaxin 7 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAPBP | TAP binding protein (tapasin) |
| TBC1D19 | TBC1 domain family, member 19 |
| TBCD | tubulin folding cofactor D |
| TCP10L | t-complex 10-like |
| TLR8 | toll-like receptor 8 |
| TONSL | tonsoku-like, DNA repair protein |
| TPMT | thiopurine S-methyltransferase |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM2 | tripartite motif containing 2 |
| UNC5B | unc-5 homolog B (C. elegans) |
| UTRN | utrophin |
| VCAN | versican |
| WDR91 | WD repeat domain 91 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF318 | zinc finger protein 318 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGO1 | argonaute RISC catalytic component 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDON | cell adhesion associated, oncogene regulated |
| CEL | carboxyl ester lipase |
| CEP85 | centrosomal protein 85kDa |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYSF | dysferlin |
| EDAR | ectodysplasin A receptor |
| EMID1 | EMI domain containing 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM120C | family with sequence similarity 120C |
| FGL1 | fibrinogen-like 1 |
| GATA4 | GATA binding protein 4 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4A | histone cluster 1, H4a |
| HMOX1 | heme oxygenase 1 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 |
| HYI | hydroxypyruvate isomerase (putative) |
| KLHL25 | kelch-like family member 25 |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL16 | methyltransferase like 16 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYO1F | myosin IF |
| NFS1 | NFS1 cysteine desulfurase |
| NPFFR1 | neuropeptide FF receptor 1 |
| ONECUT2 | one cut homeobox 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDGFD | platelet derived growth factor D |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PER3 | period circadian clock 3 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLAT | plasminogen activator, tissue |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RUNDC3B | RUN domain containing 3B |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SH2D4A | SH2 domain containing 4A |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAGLN | transgelin |
| TDRD7 | tudor domain containing 7 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TIGD6 | tigger transposable element derived 6 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TTBK2 | tau tubulin kinase 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBXN6 | UBX domain protein 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VIM | vimentin |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF428 | zinc finger protein 428 |
| ZNF747 | zinc finger protein 747 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
