nitrendipine-336 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the nitrendipine-336 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AGFG2 ArfGAP with FG repeats 2
AIM2 absent in melanoma 2
ALK anaplastic lymphoma receptor tyrosine kinase
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAM basal cell adhesion molecule (Lutheran blood group)
BIN1 bridging integrator 1
CA5A carbonic anhydrase VA, mitochondrial
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD247 CD247 molecule
CD44 CD44 molecule (Indian blood group)
CD79A CD79a molecule, immunoglobulin-associated alpha
CHERP calcium homeostasis endoplasmic reticulum protein
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLSTN2 calsyntenin 2
CNTLN centlein, centrosomal protein
COL13A1 collagen, type XIII, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DCHS1 dachsous cadherin-related 1
EPHB1 EPH receptor B1
EVI5 ecotropic viral integration site 5
EXOC6B exocyst complex component 6B
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM105A family with sequence similarity 105, member A
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT2 fucosyltransferase 2 (secretor status included)
GJA5 gap junction protein, alpha 5, 40kDa
GK glycerol kinase
GMEB1 glucocorticoid modulatory element binding protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR173 G protein-coupled receptor 173
GPX2 glutathione peroxidase 2
HOXB7 homeobox B7
HOXC5 homeobox C5
HPX hemopexin
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
IDS iduronate 2-sulfatase
IL11 interleukin 11
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL5RA interleukin 5 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LUZP1 leucine zipper protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MASP2 mannan-binding lectin serine peptidase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MINK1 misshapen-like kinase 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVB12B multivesicular body subunit 12B
MZF1 myeloid zinc finger 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NDNF neuron-derived neurotrophic factor
NF1 neurofibromin 1
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
OCA2 oculocutaneous albinism II
PARD3 par-3 family cell polarity regulator
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PARVA parvin, alpha
PDLIM4 PDZ and LIM domain 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PNMA2 paraneoplastic Ma antigen 2
PRB1 proline-rich protein BstNI subfamily 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
SCARB1 scavenger receptor class B, member 1
SCLY selenocysteine lyase
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMAD3 SMAD family member 3
SNCB synuclein, beta
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STARD8 StAR-related lipid transfer (START) domain containing 8
TBL1X transducin (beta)-like 1X-linked
TBR1 T-box, brain, 1
TCEA2 transcription elongation factor A (SII), 2
TLR6 toll-like receptor 6
TSHB thyroid stimulating hormone, beta
TTC22 tetratricopeptide repeat domain 22
USH1C Usher syndrome 1C (autosomal recessive, severe)
VAC14 Vac14 homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF117 zinc finger protein 117
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AEBP1 AE binding protein 1
AHR aryl hydrocarbon receptor
AKAP12 A kinase (PRKA) anchor protein 12
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
AMOT angiomotin
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARG1 arginase 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C16ORF59 chromosome 16 open reading frame 59
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAPN5 calpain 5
CCDC130 coiled-coil domain containing 130
CCDC94 coiled-coil domain containing 94
CCL4 chemokine (C-C motif) ligand 4
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH22 cadherin 22, type 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CRABP1 cellular retinoic acid binding protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DGAT1 diacylglycerol O-acyltransferase 1
DGKD diacylglycerol kinase, delta 130kDa
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
E4F1 E4F transcription factor 1
ECE1 endothelin converting enzyme 1
FANCE Fanconi anemia, complementation group E
FBXL2 F-box and leucine-rich repeat protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FOLR2 folate receptor 2 (fetal)
GAB2 GRB2-associated binding protein 2
GLDC glycine dehydrogenase (decarboxylating)
GPR19 G protein-coupled receptor 19
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAL histidine ammonia-lyase
HDAC11 histone deacetylase 11
HMHA1 histocompatibility (minor) HA-1
HOXC6 homeobox C6
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL4R interleukin 4 receptor
JAM2 junctional adhesion molecule 2
KDM5D lysine (K)-specific demethylase 5D
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LGALS13 lectin, galactoside-binding, soluble, 13
LHX6 LIM homeobox 6
LIAS lipoic acid synthetase
LOC100127972 uncharacterized LOC100127972
LY6D lymphocyte antigen 6 complex, locus D
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MEPE matrix extracellular phosphoglycoprotein
MON1B MON1 secretory trafficking family member B
NPPB natriuretic peptide B
OPRK1 opioid receptor, kappa 1
PCDHB3 protocadherin beta 3
PCTP phosphatidylcholine transfer protein
PGS1 phosphatidylglycerophosphate synthase 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G2E phospholipase A2, group IIE
PNMT phenylethanolamine N-methyltransferase
POGLUT1 protein O-glucosyltransferase 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB33B RAB33B, member RAS oncogene family
SATB1 SATB homeobox 1
SIL1 SIL1 nucleotide exchange factor
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPRR2B small proline-rich protein 2B
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STON1 stonin 1
SUSD4 sushi domain containing 4
SYT2 synaptotagmin II
T T, brachyury homolog (mouse)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM1 toll-like receptor adaptor molecule 1
TRAPPC12 trafficking protein particle complex 12
TSPAN5 tetraspanin 5
TSSC4 tumor suppressing subtransferable candidate 4
TUBB1 tubulin, beta 1 class VI
USP20 ubiquitin specific peptidase 20
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR13 WD repeat domain 13
WNT2 wingless-type MMTV integration site family member 2
WNT7A wingless-type MMTV integration site family, member 7A
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF329 zinc finger protein 329
ZNF528 zinc finger protein 528
ZNF668 zinc finger protein 668