| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the nitrendipine-336 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AIM2 | absent in melanoma 2 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP4A | ATPase, H+/K+ exchanging, alpha polypeptide |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BIN1 | bridging integrator 1 |
| CA5A | carbonic anhydrase VA, mitochondrial |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CD247 | CD247 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLSTN2 | calsyntenin 2 |
| CNTLN | centlein, centrosomal protein |
| COL13A1 | collagen, type XIII, alpha 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| DCHS1 | dachsous cadherin-related 1 |
| EPHB1 | EPH receptor B1 |
| EVI5 | ecotropic viral integration site 5 |
| EXOC6B | exocyst complex component 6B |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM105A | family with sequence similarity 105, member A |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GJA5 | gap junction protein, alpha 5, 40kDa |
| GK | glycerol kinase |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR173 | G protein-coupled receptor 173 |
| GPX2 | glutathione peroxidase 2 |
| HOXB7 | homeobox B7 |
| HOXC5 | homeobox C5 |
| HPX | hemopexin |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 |
| IDS | iduronate 2-sulfatase |
| IL11 | interleukin 11 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL5RA | interleukin 5 receptor, alpha |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LUZP1 | leucine zipper protein 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MINK1 | misshapen-like kinase 1 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MVB12B | multivesicular body subunit 12B |
| MZF1 | myeloid zinc finger 1 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NDNF | neuron-derived neurotrophic factor |
| NF1 | neurofibromin 1 |
| NOX1 | NADPH oxidase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OCA2 | oculocutaneous albinism II |
| PARD3 | par-3 family cell polarity regulator |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PARVA | parvin, alpha |
| PDLIM4 | PDZ and LIM domain 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| RAPGEF3 | Rap guanine nucleotide exchange factor (GEF) 3 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| SCARB1 | scavenger receptor class B, member 1 |
| SCLY | selenocysteine lyase |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SMAD3 | SMAD family member 3 |
| SNCB | synuclein, beta |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| TBL1X | transducin (beta)-like 1X-linked |
| TBR1 | T-box, brain, 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TLR6 | toll-like receptor 6 |
| TSHB | thyroid stimulating hormone, beta |
| TTC22 | tetratricopeptide repeat domain 22 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF117 | zinc finger protein 117 |
| ZNF3 | zinc finger protein 3 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| AEBP1 | AE binding protein 1 |
| AHR | aryl hydrocarbon receptor |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| AMOT | angiomotin |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARG1 | arginase 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CAPN5 | calpain 5 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC94 | coiled-coil domain containing 94 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) |
| CDH22 | cadherin 22, type 2 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 |
| E4F1 | E4F transcription factor 1 |
| ECE1 | endothelin converting enzyme 1 |
| FANCE | Fanconi anemia, complementation group E |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOLR2 | folate receptor 2 (fetal) |
| GAB2 | GRB2-associated binding protein 2 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPR19 | G protein-coupled receptor 19 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HAL | histidine ammonia-lyase |
| HDAC11 | histone deacetylase 11 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC6 | homeobox C6 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL4R | interleukin 4 receptor |
| JAM2 | junctional adhesion molecule 2 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 |
| LHX6 | LIM homeobox 6 |
| LIAS | lipoic acid synthetase |
| LOC100127972 | uncharacterized LOC100127972 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MEPE | matrix extracellular phosphoglycoprotein |
| MON1B | MON1 secretory trafficking family member B |
| NPPB | natriuretic peptide B |
| OPRK1 | opioid receptor, kappa 1 |
| PCDHB3 | protocadherin beta 3 |
| PCTP | phosphatidylcholine transfer protein |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLA2G2E | phospholipase A2, group IIE |
| PNMT | phenylethanolamine N-methyltransferase |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RAB33B | RAB33B, member RAS oncogene family |
| SATB1 | SATB homeobox 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPRR2B | small proline-rich protein 2B |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STON1 | stonin 1 |
| SUSD4 | sushi domain containing 4 |
| SYT2 | synaptotagmin II |
| T | T, brachyury homolog (mouse) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TSPAN5 | tetraspanin 5 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TUBB1 | tubulin, beta 1 class VI |
| USP20 | ubiquitin specific peptidase 20 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR13 | WD repeat domain 13 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| XYLT2 | xylosyltransferase II |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF329 | zinc finger protein 329 |
| ZNF528 | zinc finger protein 528 |
| ZNF668 | zinc finger protein 668 |