| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the nitrofurantoin-2303 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit |
| APC | adenomatous polyposis coli |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP10A | ATPase, class V, type 10A |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BEX1 | brain expressed, X-linked 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CAV2 | caveolin 2 |
| CAV3 | caveolin 3 |
| CD248 | CD248 molecule, endosialin |
| CD58 | CD58 molecule |
| CD82 | CD82 molecule |
| CD86 | CD86 molecule |
| CDC25A | cell division cycle 25A |
| CDK6 | cyclin-dependent kinase 6 |
| CEP41 | centrosomal protein 41kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| COL1A1 | collagen, type I, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DOK4 | docking protein 4 |
| EFNB3 | ephrin-B3 |
| ESR1 | estrogen receptor 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FHL1 | four and a half LIM domains 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GYG2 | glycogenin 2 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFI35 | interferon-induced protein 35 |
| IL23A | interleukin 23, alpha subunit p19 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPT | microtubule-associated protein tau |
| MEF2D | myocyte enhancer factor 2D |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MLXIP | MLX interacting protein |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCAN | neurocan |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NPR3 | natriuretic peptide receptor 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRF1 | nuclear respiratory factor 1 |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAPPA2 | pappalysin 2 |
| PARVA | parvin, alpha |
| PCLO | piccolo presynaptic cytomatrix protein |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PRAME | preferentially expressed antigen in melanoma |
| PRSS3 | protease, serine, 3 |
| PTHLH | parathyroid hormone-like hormone |
| PTRF | polymerase I and transcript release factor |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RB1 | retinoblastoma 1 |
| RBFA | ribosome binding factor A (putative) |
| RPS3A | ribosomal protein S3A |
| RUNX1 | runt-related transcription factor 1 |
| S100A2 | S100 calcium binding protein A2 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC7A4 | solute carrier family 7, member 4 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| STAC | SH3 and cysteine rich domain |
| THBD | thrombomodulin |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM212 | transmembrane protein 212 |
| TPM2 | tropomyosin 2 (beta) |
| TRIM29 | tripartite motif containing 29 |
| UPK1B | uroplakin 1B |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| XYLT1 | xylosyltransferase I |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADM | adrenomedullin |
| ALPK1 | alpha-kinase 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C5AR2 | complement component 5a receptor 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN15 | calpain 15 |
| CBX8 | chromobox homolog 8 |
| CCDC186 | coiled-coil domain containing 186 |
| CDK3 | cyclin-dependent kinase 3 |
| CENPC | centromere protein C |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUL9 | cullin 9 |
| CXORF56 | chromosome X open reading frame 56 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DOCK4 | dedicator of cytokinesis 4 |
| DOK2 | docking protein 2, 56kDa |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM131A | family with sequence similarity 131, member A |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FOXC1 | forkhead box C1 |
| FPGS | folylpolyglutamate synthase |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTM5 | glutathione S-transferase mu 5 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BJ | histone cluster 1, H2bj |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HYI | hydroxypyruvate isomerase (putative) |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIF13A | kinesin family member 13A |
| KIFC1 | kinesin family member C1 |
| KLHL25 | kelch-like family member 25 |
| LHX1 | LIM homeobox 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| MEFV | Mediterranean fever |
| MNX1 | motor neuron and pancreas homeobox 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NMU | neuromedin U |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSMR | oncostatin M receptor |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMP22 | peripheral myelin protein 22 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RLN1 | relaxin 1 |
| RNF122 | ring finger protein 122 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMTN | smoothelin |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAB2 | stabilin 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VASH2 | vasohibin 2 |
| WDR76 | WD repeat domain 76 |
| XK | X-linked Kx blood group |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF480 | zinc finger protein 480 |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
| ZNF770 | zinc finger protein 770 |