| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the nitrofurantoin-4697 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| AJAP1 | adherens junctions associated protein 1 |
| AK1 | adenylate kinase 1 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| BCL2A1 | BCL2-related protein A1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTG2 | BTG family, member 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC121 | coiled-coil domain containing 121 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD248 | CD248 molecule, endosialin |
| CD34 | CD34 molecule |
| CD58 | CD58 molecule |
| CDC25C | cell division cycle 25C |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CREM | cAMP responsive element modulator |
| CYHR1 | cysteine/histidine-rich 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EMC1 | ER membrane protein complex subunit 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV6 | ets variant 6 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EXPH5 | exophilin 5 |
| FANCA | Fanconi anemia, complementation group A |
| FBLN1 | fibulin 1 |
| FCGBP | Fc fragment of IgG binding protein |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FMOD | fibromodulin |
| FRZB | frizzled-related protein |
| FSCN1 | fascin actin-bundling protein 1 |
| GALC | galactosylceramidase |
| GFI1 | growth factor independent 1 transcription repressor |
| GHRHR | growth hormone releasing hormone receptor |
| GID4 | GID complex subunit 4 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GNRHR | gonadotropin-releasing hormone receptor |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HFE | hemochromatosis |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H3E | histone cluster 1, H3e |
| HOXA1 | homeobox A1 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL23A | interleukin 23, alpha subunit p19 |
| IL5RA | interleukin 5 receptor, alpha |
| ING4 | inhibitor of growth family, member 4 |
| JMJD4 | jumonji domain containing 4 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KLF2 | Kruppel-like factor 2 |
| KRT17 | keratin 17, type I |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPIN1 | lipin 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| MNDA | myeloid cell nuclear differentiation antigen |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCOA2 | nuclear receptor coactivator 2 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PARD6B | par-6 family cell polarity regulator beta |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PLAC1 | placenta-specific 1 |
| PLVAP | plasmalemma vesicle associated protein |
| PSCA | prostate stem cell antigen |
| QKI | QKI, KH domain containing, RNA binding |
| QSER1 | glutamine and serine rich 1 |
| RAB6B | RAB6B, member RAS oncogene family |
| RBBP9 | retinoblastoma binding protein 9 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RIN3 | Ras and Rab interactor 3 |
| RS1 | retinoschisin 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCRN3 | secernin 3 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BP1 | SH3-domain binding protein 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| TAPBP | TAP binding protein (tapasin) |
| TFF2 | trefoil factor 2 |
| TMEM19 | transmembrane protein 19 |
| VWA5A | von Willebrand factor A domain containing 5A |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZFP64 | ZFP64 zinc finger protein |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ARC | activity-regulated cytoskeleton-associated protein |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CAPN5 | calpain 5 |
| CCDC132 | coiled-coil domain containing 132 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDHR2 | cadherin-related family member 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORT | cortistatin |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DSCAM | Down syndrome cell adhesion molecule |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP8 | dual specificity phosphatase 8 |
| DYSF | dysferlin |
| ERCC4 | excision repair cross-complementation group 4 |
| FANCC | Fanconi anemia, complementation group C |
| FGF23 | fibroblast growth factor 23 |
| FLCN | folliculin |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GAMT | guanidinoacetate N-methyltransferase |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| HPN | hepsin |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM8 | lysine (K)-specific demethylase 8 |
| KRT31 | keratin 31, type I |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MFAP2 | microfibrillar-associated protein 2 |
| MUC3B | mucin 3B, cell surface associated |
| MYLK | myosin light chain kinase |
| MYO1F | myosin IF |
| N4BP3 | NEDD4 binding protein 3 |
| NAG18 | NAG18 mRNA |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCAM2 | neural cell adhesion molecule 2 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEUROD1 | neuronal differentiation 1 |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGP | phosphoglycolate phosphatase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITX2 | paired-like homeodomain 2 |
| PLAT | plasminogen activator, tissue |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| QPCT | glutaminyl-peptide cyclotransferase |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF208 | ring finger protein 208 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| SAA3P | serum amyloid A3 pseudogene |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SP1 | Sp1 transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRYD7 | SPRY domain containing 7 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TH | tyrosine hydroxylase |
| THBS3 | thrombospondin 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM120B | transmembrane protein 120B |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TNS2 | tensin 2 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBA3D | tubulin, alpha 3d |
| TUBB2B | tubulin, beta 2B class IIb |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF675 | zinc finger protein 675 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |