Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the nitrofurantoin-7373 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AAGAB | alpha- and gamma-adaptin binding protein |
ADGRL1 | adhesion G protein-coupled receptor L1 |
ANXA10 | annexin A10 |
APOM | apolipoprotein M |
ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
BTG2 | BTG family, member 2 |
CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
CCDC93 | coiled-coil domain containing 93 |
CCNT2 | cyclin T2 |
CDC14B | cell division cycle 14B |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CFLAR | CASP8 and FADD-like apoptosis regulator |
CHRM3 | cholinergic receptor, muscarinic 3 |
CNTNAP2 | contactin associated protein-like 2 |
CTNND2 | catenin (cadherin-associated protein), delta 2 |
CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
DOHH | deoxyhypusine hydroxylase/monooxygenase |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EHBP1L1 | EH domain binding protein 1-like 1 |
EPAS1 | endothelial PAS domain protein 1 |
ERO1LB | ERO1-like beta (S. cerevisiae) |
EXOC6B | exocyst complex component 6B |
FCF1 | FCF1 rRNA-processing protein |
FGFR1 | fibroblast growth factor receptor 1 |
GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
GPR161 | G protein-coupled receptor 161 |
GRK5 | G protein-coupled receptor kinase 5 |
HIST1H1E | histone cluster 1, H1e |
HIST3H3 | histone cluster 3, H3 |
HOXA4 | homeobox A4 |
HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
IL12A | interleukin 12A |
IL15 | interleukin 15 |
KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
KITLG | KIT ligand |
KRTAP9-9 | keratin associated protein 9-9 |
LIG3 | ligase III, DNA, ATP-dependent |
LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
LOC399491 | |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
MAGEH1 | melanoma antigen family H1 |
MED31 | mediator complex subunit 31 |
MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
MMP13 | matrix metallopeptidase 13 |
MRPL57 | mitochondrial ribosomal protein L57 |
MYO7A | myosin VIIA |
MYOZ3 | myozenin 3 |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
OAZ3 | ornithine decarboxylase antizyme 3 |
PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
PCOLCE | procollagen C-endopeptidase enhancer |
PGAP1 | post-GPI attachment to proteins 1 |
PGM5 | phosphoglucomutase 5 |
PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
PTBP3 | polypyrimidine tract binding protein 3 |
PTGDR2 | prostaglandin D2 receptor 2 |
PVT1 | Pvt1 oncogene (non-protein coding) |
RAB31 | RAB31, member RAS oncogene family |
RAB3A | RAB3A, member RAS oncogene family |
RARG | retinoic acid receptor, gamma |
RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
RGS7 | regulator of G-protein signaling 7 |
RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
RPAP2 | RNA polymerase II associated protein 2 |
SAMD4B | sterile alpha motif domain containing 4B |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SENP6 | SUMO1/sentrin specific peptidase 6 |
SERBP1 | SERPINE1 mRNA binding protein 1 |
SERTAD3 | SERTA domain containing 3 |
SIRT3 | sirtuin 3 |
SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
SOX30 | SRY (sex determining region Y)-box 30 |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
SYN2 | synapsin II |
TBCD | tubulin folding cofactor D |
TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
TLE4 | transducin-like enhancer of split 4 |
TMCO6 | transmembrane and coiled-coil domains 6 |
TRAV8-3 | T cell receptor alpha variable 8-3 |
TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
TYRO3 | TYRO3 protein tyrosine kinase |
ULK2 | unc-51 like autophagy activating kinase 2 |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
XYLB | xylulokinase homolog (H. influenzae) |
YTHDC1 | YTH domain containing 1 |
ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
ZNF768 | zinc finger protein 768 |
Symbol | Name |
---|---|
ADAM15 | ADAM metallopeptidase domain 15 |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
ANG | angiogenin, ribonuclease, RNase A family, 5 |
ARHGAP12 | Rho GTPase activating protein 12 |
ARMC6 | armadillo repeat containing 6 |
ASCC2 | activating signal cointegrator 1 complex subunit 2 |
ATAD2B | ATPase family, AAA domain containing 2B |
ATOX1 | antioxidant 1 copper chaperone |
BAG4 | BCL2-associated athanogene 4 |
C9ORF91 | chromosome 9 open reading frame 91 |
CAPN5 | calpain 5 |
CCDC106 | coiled-coil domain containing 106 |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
CDH7 | cadherin 7, type 2 |
CLDN15 | claudin 15 |
CLEC10A | C-type lectin domain family 10, member A |
CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
CTSK | cathepsin K |
CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
CYB5R1 | cytochrome b5 reductase 1 |
DCAF13 | DDB1 and CUL4 associated factor 13 |
DDIT4 | DNA-damage-inducible transcript 4 |
DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
EDC3 | enhancer of mRNA decapping 3 |
ELP6 | elongator acetyltransferase complex subunit 6 |
ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
ETV4 | ets variant 4 |
FAM102A | family with sequence similarity 102, member A |
FBXO5 | F-box protein 5 |
FCHO1 | FCH domain only 1 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GLDC | glycine dehydrogenase (decarboxylating) |
GRPR | gastrin-releasing peptide receptor |
GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
HIST1H2AJ | histone cluster 1, H2aj |
IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
IREB2 | iron-responsive element binding protein 2 |
KIF16B | kinesin family member 16B |
LIMS2 | LIM and senescent cell antigen-like domains 2 |
LNPEP | leucyl/cystinyl aminopeptidase |
LPAR3 | lysophosphatidic acid receptor 3 |
LY6G5C | lymphocyte antigen 6 complex, locus G5C |
LYRM2 | LYR motif containing 2 |
MACROD1 | MACRO domain containing 1 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MBIP | MAP3K12 binding inhibitory protein 1 |
MCC | mutated in colorectal cancers |
MFGE8 | milk fat globule-EGF factor 8 protein |
MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
MYL5 | myosin, light chain 5, regulatory |
MYO1D | myosin ID |
NABP2 | nucleic acid binding protein 2 |
NCS1 | neuronal calcium sensor 1 |
NECAP2 | NECAP endocytosis associated 2 |
OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
PLCD1 | phospholipase C, delta 1 |
PRPF8 | pre-mRNA processing factor 8 |
PRR7 | proline rich 7 (synaptic) |
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RANBP17 | RAN binding protein 17 |
RBM47 | RNA binding motif protein 47 |
REV1 | REV1, polymerase (DNA directed) |
RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
RHOC | ras homolog family member C |
RNF170 | ring finger protein 170 |
RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
S100A9 | S100 calcium binding protein A9 |
SAMD9 | sterile alpha motif domain containing 9 |
SCEL | sciellin |
SEPP1 | selenoprotein P, plasma, 1 |
SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
SLC25A40 | solute carrier family 25, member 40 |
SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
SYTL2 | synaptotagmin-like 2 |
TBX19 | T-box 19 |
TLR2 | toll-like receptor 2 |
TMC7 | transmembrane channel-like 7 |
TMEM2 | transmembrane protein 2 |
TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
TRAPPC2 | trafficking protein particle complex 2 |
TRIM9 | tripartite motif containing 9 |
TSPAN15 | tetraspanin 15 |
VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
WDR76 | WD repeat domain 76 |
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
ZBTB44 | zinc finger and BTB domain containing 44 |
ZMAT5 | zinc finger, matrin-type 5 |
ZNF282 | zinc finger protein 282 |
ZNF34 | zinc finger protein 34 |
ZNF480 | zinc finger protein 480 |
ZNF552 | zinc finger protein 552 |
ZNF668 | zinc finger protein 668 |