| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nizatidine-3385 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AIM1L | absent in melanoma 1-like |
| AK1 | adenylate kinase 1 |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARSD | arylsulfatase D |
| ATG10 | autophagy related 10 |
| B9D1 | B9 protein domain 1 |
| BARX2 | BARX homeobox 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMP8B | bone morphogenetic protein 8b |
| BMX | BMX non-receptor tyrosine kinase |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C2 | complement component 2 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CDH8 | cadherin 8, type 2 |
| CEP41 | centrosomal protein 41kDa |
| CES3 | carboxylesterase 3 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPQ | carboxypeptidase Q |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DOC2A | double C2-like domains, alpha |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ECE1 | endothelin converting enzyme 1 |
| EDN1 | endothelin 1 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EMC3 | ER membrane protein complex subunit 3 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FABP6 | fatty acid binding protein 6, ileal |
| FBXO4 | F-box protein 4 |
| FGF6 | fibroblast growth factor 6 |
| FHL1 | four and a half LIM domains 1 |
| FRMD1 | FERM domain containing 1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| HOXD11 | homeobox D11 |
| HSF4 | heat shock transcription factor 4 |
| ICAM2 | intercellular adhesion molecule 2 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL1B | interleukin 1, beta |
| IL22 | interleukin 22 |
| IRF4 | interferon regulatory factor 4 |
| ITGB5 | integrin, beta 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| LATS1 | large tumor suppressor kinase 1 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYOF | myoferlin |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEFL | neurofilament, light polypeptide |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAX9 | paired box 9 |
| PCDH17 | protocadherin 17 |
| PCDHA9 | protocadherin alpha 9 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB40C | RAB40C, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| SALL1 | spalt-like transcription factor 1 |
| SCLY | selenocysteine lyase |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERHL2 | serine hydrolase-like 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSTR5 | somatostatin receptor 5 |
| STAT4 | signal transducer and activator of transcription 4 |
| TAGLN3 | transgelin 3 |
| TBX6 | T-box 6 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TXNRD2 | thioredoxin reductase 2 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZNF286A | zinc finger protein 286A |
| ZNF518A | zinc finger protein 518A |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| B9D2 | B9 protein domain 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QB | complement component 1, q subcomponent, B chain |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBX8 | chromobox homolog 8 |
| CD82 | CD82 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| DBF4B | DBF4 zinc finger B |
| DBR1 | debranching RNA lariats 1 |
| DEAF1 | DEAF1 transcription factor |
| DVL1 | dishevelled segment polarity protein 1 |
| EDAR | ectodysplasin A receptor |
| EMID1 | EMI domain containing 1 |
| FAM186A | family with sequence similarity 186, member A |
| FSCN1 | fascin actin-bundling protein 1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR21 | G protein-coupled receptor 21 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H4D | histone cluster 1, H4d |
| HOXC11 | homeobox C11 |
| HOXC5 | homeobox C5 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KRT24 | keratin 24, type I |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LMTK2 | lemur tyrosine kinase 2 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MICALL2 | MICAL-like 2 |
| MON1B | MON1 secretory trafficking family member B |
| MUC3A | mucin 3A, cell surface associated |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PALM | paralemmin |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDE8B | phosphodiesterase 8B |
| PGM1 | phosphoglucomutase 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLXNB3 | plexin B3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLM | polymerase (DNA directed), mu |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RND1 | Rho family GTPase 1 |
| RPL10L | ribosomal protein L10-like |
| SAV1 | salvador family WW domain containing protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEX40 | testis expressed 40 |
| TLR5 | toll-like receptor 5 |
| TMEM209 | transmembrane protein 209 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TPCN1 | two pore segment channel 1 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSGA10 | testis specific, 10 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR78 | WD repeat domain 78 |
| XYLT1 | xylosyltransferase I |
| ZNF136 | zinc finger protein 136 |
| ZNF639 | zinc finger protein 639 |
