| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the nizatidine-5406 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| AHI1 | Abelson helper integration site 1 |
| AK1 | adenylate kinase 1 |
| APOC1 | apolipoprotein C-I |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATP10B | ATPase, class V, type 10B |
| C18ORF25 | chromosome 18 open reading frame 25 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CCPG1 | cell cycle progression 1 |
| CDC42 | cell division cycle 42 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLMN | calmin (calponin-like, transmembrane) |
| CLPS | colipase, pancreatic |
| CLTC | clathrin, heavy chain (Hc) |
| COMMD4 | COMM domain containing 4 |
| CORO7 | coronin 7 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTSZ | cathepsin Z |
| DTNA | dystrobrevin, alpha |
| ELL | elongation factor RNA polymerase II |
| EPHA3 | EPH receptor A3 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO11 | F-box protein 11 |
| FBXO9 | F-box protein 9 |
| FHL1 | four and a half LIM domains 1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GM2A | GM2 ganglioside activator |
| GPATCH4 | G patch domain containing 4 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR137 | G protein-coupled receptor 137 |
| HFE | hemochromatosis |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HRASLS2 | HRAS-like suppressor 2 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| JMJD4 | jumonji domain containing 4 |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LRRC15 | leucine rich repeat containing 15 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MGAT4C | MGAT4 family, member C |
| MTAP | methylthioadenosine phosphorylase |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NEK1 | NIMA-related kinase 1 |
| NKX6-1 | NK6 homeobox 1 |
| NUP54 | nucleoporin 54kDa |
| NXPH4 | neurexophilin 4 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDCL | phosducin-like |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLK3 | polo-like kinase 3 |
| POU4F1 | POU class 4 homeobox 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRND | prion protein 2 (dublet) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RGS6 | regulator of G-protein signaling 6 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SIK3 | SIK family kinase 3 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STC1 | stanniocalcin 1 |
| SUMO1 | small ubiquitin-like modifier 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TBL2 | transducin (beta)-like 2 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAV8-3 | T cell receptor alpha variable 8-3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WIZ | widely interspaced zinc finger motifs |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YIPF4 | Yip1 domain family, member 4 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZIC3 | Zic family member 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF484 | zinc finger protein 484 |
| ZNF609 | zinc finger protein 609 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ACTL8 | actin-like 8 |
| AEBP1 | AE binding protein 1 |
| AGO1 | argonaute RISC catalytic component 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARMC7 | armadillo repeat containing 7 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B9D2 | B9 protein domain 2 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BLNK | B-cell linker |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CBX7 | chromobox homolog 7 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIC | capicua transcriptional repressor |
| CLEC4E | C-type lectin domain family 4, member E |
| CLIC2 | chloride intracellular channel 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DIXDC1 | DIX domain containing 1 |
| DOC2A | double C2-like domains, alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPPK1 | epiplakin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETNK2 | ethanolamine kinase 2 |
| ETV6 | ets variant 6 |
| FAM46C | family with sequence similarity 46, member C |
| GAS2 | growth arrest-specific 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR143 | G protein-coupled receptor 143 |
| HDAC11 | histone deacetylase 11 |
| HDAC5 | histone deacetylase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HOXC10 | homeobox C10 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT54 | intraflagellar transport 54 |
| IRF1 | interferon regulatory factor 1 |
| KLF2 | Kruppel-like factor 2 |
| KRT13 | keratin 13, type I |
| KRT15 | keratin 15, type I |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1E | myosin IE |
| MYOZ3 | myozenin 3 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NLRX1 | NLR family member X1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCDHA6 | protocadherin alpha 6 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RNF122 | ring finger protein 122 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A9 | S100 calcium binding protein A9 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD1A | SET domain containing 1A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPAG4 | sperm associated antigen 4 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TRAIP | TRAF interacting protein |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBTD1 | ubiquitin domain containing 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFB | vascular endothelial growth factor B |
| WDR25 | WD repeat domain 25 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF254 | zinc finger protein 254 |
| ZNF506 | zinc finger protein 506 |
| ZNF606 | zinc finger protein 606 |
