| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nizatidine-6305 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALOX12 | arachidonate 12-lipoxygenase |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANXA10 | annexin A10 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| CEP162 | centrosomal protein 162kDa |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CST4 | cystatin S |
| CUL9 | cullin 9 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DMD | dystrophin |
| DRD2 | dopamine receptor D2 |
| DTNA | dystrobrevin, alpha |
| DVL2 | dishevelled segment polarity protein 2 |
| EDAR | ectodysplasin A receptor |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FGF5 | fibroblast growth factor 5 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGL1 | fibrinogen-like 1 |
| GATA2 | GATA binding protein 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HEMK1 | HemK methyltransferase family member 1 |
| HMG20B | high mobility group 20B |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| INADL | InaD-like (Drosophila) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIF1A | kinesin family member 1A |
| KLHL28 | kelch-like family member 28 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT32 | keratin 32, type I |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LOC257152 | uncharacterized LOC257152 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP7 | microtubule-associated protein 7 |
| MED28 | mediator complex subunit 28 |
| MEGF6 | multiple EGF-like-domains 6 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC1 | mucin 1, cell surface associated |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NINJ1 | ninjurin 1 |
| NPEPL1 | aminopeptidase-like 1 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NTNG1 | netrin G1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDLIM4 | PDZ and LIM domain 4 |
| PIDD1 | p53-induced death domain protein 1 |
| PKP4 | plakophilin 4 |
| PLA2G3 | phospholipase A2, group III |
| PLCH1 | phospholipase C, eta 1 |
| PLD3 | phospholipase D family, member 3 |
| PLIN2 | perilipin 2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKCA | protein kinase C, alpha |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PURA | purine-rich element binding protein A |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RANBP1 | RAN binding protein 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RNF39 | ring finger protein 39 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SIRT5 | sirtuin 5 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STAG3 | stromal antigen 3 |
| STK17B | serine/threonine kinase 17b |
| STX2 | syntaxin 2 |
| TEP1 | telomerase-associated protein 1 |
| TK2 | thymidine kinase 2, mitochondrial |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TTC9 | tetratricopeptide repeat domain 9 |
| USP19 | ubiquitin specific peptidase 19 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| VWA5A | von Willebrand factor A domain containing 5A |
| YY2 | YY2 transcription factor |
| ZHX3 | zinc fingers and homeoboxes 3 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| AZI2 | 5-azacytidine induced 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BEX1 | brain expressed, X-linked 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHMP6 | charged multivesicular body protein 6 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like |
| CRIP2 | cysteine-rich protein 2 |
| CRYBA2 | crystallin, beta A2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CXORF56 | chromosome X open reading frame 56 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DSPP | dentin sialophosphoprotein |
| ECM1 | extracellular matrix protein 1 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| FER | fer (fps/fes related) tyrosine kinase |
| FMO4 | flavin containing monooxygenase 4 |
| GALE | UDP-galactose-4-epimerase |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLCE | glucuronic acid epimerase |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR176 | G protein-coupled receptor 176 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H3B | histone cluster 1, H3b |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM4D | lysine (K)-specific demethylase 4D |
| KIF18A | kinesin family member 18A |
| KLC2 | kinesin light chain 2 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC730101 | uncharacterized LOC730101 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAGEF1 | melanoma antigen family F1 |
| MICALL2 | MICAL-like 2 |
| MUC7 | mucin 7, secreted |
| MYL9 | myosin, light chain 9, regulatory |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRTN | neurturin |
| ONECUT2 | one cut homeobox 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALMD | palmdelphin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PRPH | peripherin |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RAB8B | RAB8B, member RAS oncogene family |
| RASA2 | RAS p21 protein activator 2 |
| RECQL4 | RecQ protein-like 4 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETBP1 | SET binding protein 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SYNPO | synaptopodin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TPK1 | thiamin pyrophosphokinase 1 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UROS | uroporphyrinogen III synthase |
| XAB2 | XPA binding protein 2 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF165 | zinc finger protein 165 |
| ZNF197 | zinc finger protein 197 |
| ZNF324 | zinc finger protein 324 |
| ZNF350 | zinc finger protein 350 |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF675 | zinc finger protein 675 |
| ZNF816 | zinc finger protein 816 |
