nocodazole-1393 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the nocodazole-1393 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE2 adhesion G protein-coupled receptor E2
AHR aryl hydrocarbon receptor
ANKRD12 ankyrin repeat domain 12
ANXA2 annexin A2
AREG amphiregulin
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARL4C ADP-ribosylation factor-like 4C
ARRB2 arrestin, beta 2
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BCL2A1 BCL2-related protein A1
BCL3 B-cell CLL/lymphoma 3
BTG1 B-cell translocation gene 1, anti-proliferative
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CD86 CD86 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CLDND1 claudin domain containing 1
CLIP1 CAP-GLY domain containing linker protein 1
CLK1 CDC-like kinase 1
CREM cAMP responsive element modulator
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CYLD cylindromatosis (turban tumor syndrome)
CYTH1 cytohesin 1
CYTIP cytohesin 1 interacting protein
DOCK4 dedicator of cytokinesis 4
DPY19L4 dpy-19-like 4 (C. elegans)
DUSP4 dual specificity phosphatase 4
ECT2 epithelial cell transforming 2
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
G0S2 G0/G1 switch 2
GAB2 GRB2-associated binding protein 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR183 G protein-coupled receptor 183
H2BFS H2B histone family, member S (pseudogene)
HBEGF heparin-binding EGF-like growth factor
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IER3 immediate early response 3
IFRD1 interferon-related developmental regulator 1
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
KIF23 kinesin family member 23
KLF10 Kruppel-like factor 10
KRIT1 KRIT1, ankyrin repeat containing
KYNU kynureninase
LASP1 LIM and SH3 protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALT1 MALT1 paracaspase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
N4BP2L2 NEDD4 binding protein 2-like 2
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NAMPT nicotinamide phosphoribosyltransferase
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAUR plasminogen activator, urokinase receptor
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
PLSCR1 phospholipid scramblase 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPARD peroxisome proliferator-activated receptor delta
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTX3 pentraxin 3, long
RAP2C RAP2C, member of RAS oncogene family
RGS2 regulator of G-protein signaling 2
RIOK3 RIO kinase 3
RNF19B ring finger protein 19B
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS2 ribosomal protein S2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SH2B3 SH2B adaptor protein 3
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SMIM7 small integral membrane protein 7
SMOX spermine oxidase
STXBP3 syntaxin binding protein 3
TANK TRAF family member-associated NFKB activator
THBS1 thrombospondin 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPM4 tropomyosin 4
TREM1 triggering receptor expressed on myeloid cells 1
TRIB1 tribbles pseudokinase 1
VEZF1 vascular endothelial zinc finger 1
WIPF1 WAS/WASL interacting protein family, member 1
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ACY1 aminoacylase 1
ADGRA3 adhesion G protein-coupled receptor A3
ADRB2 adrenoceptor beta 2, surface
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ASB13 ankyrin repeat and SOCS box containing 13
ASNS asparagine synthetase (glutamine-hydrolyzing)
C10ORF2 chromosome 10 open reading frame 2
CBR1 carbonyl reductase 1
CCL2 chemokine (C-C motif) ligand 2
CD3EAP CD3e molecule, epsilon associated protein
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLTCL1 clathrin, heavy chain-like 1
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTH cystathionine gamma-lyase
DCPS decapping enzyme, scavenger
DEAF1 DEAF1 transcription factor
EBNA1BP2 EBNA1 binding protein 2
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELANE elastase, neutrophil expressed
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENDOG endonuclease G
EXOSC5 exosome component 5
FAM216A family with sequence similarity 216, member A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FLT3 fms-related tyrosine kinase 3
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FYCO1 FYVE and coiled-coil domain containing 1
GEMIN4 gem (nuclear organelle) associated protein 4
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPE1 heat shock 10kDa protein 1
IRF8 interferon regulatory factor 8
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0020 KIAA0020
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MEST mesoderm specific transcript
METTL1 methyltransferase like 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MPV17 MpV17 mitochondrial inner membrane protein
MRPL24 mitochondrial ribosomal protein L24
MRPL3 mitochondrial ribosomal protein L3
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTG1 mitochondrial ribosome-associated GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NAT10 N-acetyltransferase 10 (GCN5-related)
NCF1C neutrophil cytosolic factor 1C pseudogene
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOL8 nucleolar protein 8
ODC1 ornithine decarboxylase 1
ORM1 orosomucoid 1
OSGEP O-sialoglycoprotein endopeptidase
PAAF1 proteasomal ATPase-associated factor 1
PCCB propionyl CoA carboxylase, beta polypeptide
PCYOX1L prenylcysteine oxidase 1 like
PES1 pescadillo ribosomal biogenesis factor 1
PFAS phosphoribosylformylglycinamidine synthase
PHGDH phosphoglycerate dehydrogenase
PLAC8 placenta-specific 8
PMPCA peptidase (mitochondrial processing) alpha
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPAN peter pan homolog (Drosophila)
PRTN3 proteinase 3
PSAT1 phosphoserine aminotransferase 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PUS7 pseudouridylate synthase 7 (putative)
QPRT quinolinate phosphoribosyltransferase
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SMYD3 SET and MYND domain containing 3
SPP1 secreted phosphoprotein 1
SRM spermidine synthase
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STRA13 stimulated by retinoic acid 13
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TFB2M transcription factor B2, mitochondrial
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TRAPPC2L trafficking protein particle complex 2-like
UCK2 uridine-cytidine kinase 2
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WDR12 WD repeat domain 12
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43