nocodazole-2239 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nocodazole-2239 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE3 adhesion G protein-coupled receptor E3
AREG amphiregulin
ARMC8 armadillo repeat containing 8
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF3 activating transcription factor 3
ATG5 autophagy related 5
BAG1 BCL2-associated athanogene
BCAN brevican
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALCR calcitonin receptor
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN7 chloride channel, voltage-sensitive 7
CLK1 CDC-like kinase 1
CLN5 ceroid-lipofuscinosis, neuronal 5
COL6A1 collagen, type VI, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CUL3 cullin 3
DDIT3 DNA-damage-inducible transcript 3
DHODH dihydroorotate dehydrogenase (quinone)
DTNA dystrobrevin, alpha
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EGR1 early growth response 1
EGR3 early growth response 3
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4A1 eukaryotic translation initiation factor 4A1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFR1 fibroblast growth factor receptor 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRSF1 G-rich RNA sequence binding factor 1
HBEGF heparin-binding EGF-like growth factor
HEG1 heart development protein with EGF-like domains 1
HIC2 hypermethylated in cancer 2
HOXA7 homeobox A7
ICOSLG inducible T-cell co-stimulator ligand
IL17RC interleukin 17 receptor C
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0141 KIAA0141
KLF6 Kruppel-like factor 6
LIF leukemia inhibitory factor
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC157562 uncharacterized LOC157562
LOX lysyl oxidase
LPIN1 lipin 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
LZTFL1 leucine zipper transcription factor-like 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA6 melanoma antigen family A6
MALL mal, T-cell differentiation protein-like
MID2 midline 2
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
N4BP2L2 NEDD4 binding protein 2-like 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NPFF neuropeptide FF-amide peptide precursor
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK3 polo-like kinase 3
PLSCR4 phospholipid scramblase 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTPRE protein tyrosine phosphatase, receptor type, E
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM8A RNA binding motif protein 8A
RPL28 ribosomal protein L28
RPL31 ribosomal protein L31
RSL1D1 ribosomal L1 domain containing 1
S100A11 S100 calcium binding protein A11
SARM1 sterile alpha and TIR motif containing 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SH3BP2 SH3-domain binding protein 2
SH3GLB1 SH3-domain GRB2-like endophilin B1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMIM7 small integral membrane protein 7
SMOX spermine oxidase
SMYD2 SET and MYND domain containing 2
SPG20 spastic paraplegia 20 (Troyer syndrome)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STOML1 stomatin (EPB72)-like 1
TRIM29 tripartite motif containing 29
TSFM Ts translation elongation factor, mitochondrial
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VCAN versican
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR55 WD repeat domain 55
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZNF423 zinc finger protein 423
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ARMCX2 armadillo repeat containing, X-linked 2
ARMCX5 armadillo repeat containing, X-linked 5
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCLAF1 BCL2-associated transcription factor 1
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C14ORF79 chromosome 14 open reading frame 79
C14ORF93 chromosome 14 open reading frame 93
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
C4ORF29 chromosome 4 open reading frame 29
C9ORF9 chromosome 9 open reading frame 9
CBX8 chromobox homolog 8
CCDC121 coiled-coil domain containing 121
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK18 cyclin-dependent kinase 18
CDON cell adhesion associated, oncogene regulated
CEL carboxyl ester lipase
CNR2 cannabinoid receptor 2 (macrophage)
CSF1R colony stimulating factor 1 receptor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DACH1 dachshund family transcription factor 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM110B family with sequence similarity 110, member B
FAM169A family with sequence similarity 169, member A
FAM46C family with sequence similarity 46, member C
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
GATA4 GATA binding protein 4
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTM5 glutathione S-transferase mu 5
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCFC2 host cell factor C2
HIST1H2AK histone cluster 1, H2ak
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL17RB interleukin 17 receptor B
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
LIN7B lin-7 homolog B (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LOC730101 uncharacterized LOC730101
LRP2 low density lipoprotein receptor-related protein 2
LY6D lymphocyte antigen 6 complex, locus D
MSI1 musashi RNA-binding protein 1
NOL10 nucleolar protein 10
NXPE3 neurexophilin and PC-esterase domain family, member 3
OVOL1 ovo-like zinc finger 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARG poly (ADP-ribose) glycohydrolase
PICK1 protein interacting with PRKCA 1
POM121 POM121 transmembrane nucleoporin
PRR15L proline rich 15-like
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RBM4B RNA binding motif protein 4B
RCOR3 REST corepressor 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF170 ring finger protein 170
RNF2 ring finger protein 2
RRAGB Ras-related GTP binding B
SALL2 spalt-like transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SFT2D2 SFT2 domain containing 2
SIPA1 signal-induced proliferation-associated 1
SIX1 SIX homeobox 1
SLIT2 slit homolog 2 (Drosophila)
SMC6 structural maintenance of chromosomes 6
STON1 stonin 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBX19 T-box 19
TMCC2 transmembrane and coiled-coil domain family 2
TMEM121 transmembrane protein 121
TRIM45 tripartite motif containing 45
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
USP27X ubiquitin specific peptidase 27, X-linked
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VIM vimentin
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
XDH xanthine dehydrogenase
ZNF134 zinc finger protein 134
ZNF16 zinc finger protein 16
ZNF446 zinc finger protein 446
ZNF532 zinc finger protein 532
ZSCAN31 zinc finger and SCAN domain containing 31