nodal Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description nodal growth differentiation factor|The protein encoded by this gene is a member of the TGF-beta superfamily. Studies of the mouse counterpart suggested that this gene may be essential for mesoderm formation and subsequent organization of axial structures in early embryonic development. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4838)
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Genes

172 genes co-occuring with the biological term nodal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACOT8 acyl-CoA thioesterase 8
ACVR2A activin A receptor, type IIA
ADGRG1 adhesion G protein-coupled receptor G1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ANXA1 annexin A1
ASS1 argininosuccinate synthase 1
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB1 cyclin B1
CCND1 cyclin D1
CCNG2 cyclin G2
CCR9 chemokine (C-C motif) receptor 9
CD151 CD151 molecule (Raph blood group)
CD247 CD247 molecule
CD276 CD276 molecule
CD44 CD44 molecule (Indian blood group)
CD5 CD5 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CNTNAP2 contactin associated protein-like 2
CRP C-reactive protein, pentraxin-related
CSTA cystatin A (stefin A)
CTNNBIP1 catenin, beta interacting protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DAZL deleted in azoospermia-like
DHFR dihydrofolate reductase
DPYD dihydropyrimidine dehydrogenase
EGFR epidermal growth factor receptor
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
FABP4 fatty acid binding protein 4, adipocyte
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FCRL4 Fc receptor-like 4
FERMT2 fermitin family member 2
FGFR4 fibroblast growth factor receptor 4
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FOXH1 forkhead box H1
FOXO3 forkhead box O3
FOXP1 forkhead box P1
GCSAM germinal center-associated, signaling and motility
GDF1 growth differentiation factor 1
GDF3 growth differentiation factor 3
GJA1 gap junction protein, alpha 1, 43kDa
GSK3B glycogen synthase kinase 3 beta
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HLA-A major histocompatibility complex, class I, A
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
ICAM1 intercellular adhesion molecule 1
IFITM3 interferon induced transmembrane protein 3
IGH immunoglobulin heavy locus
IL3 interleukin 3
INHBA inhibin, beta A
INS insulin
IREB2 iron-responsive element binding protein 2
KIF3A kinesin family member 3A
KLK4 kallikrein-related peptidase 4
KRT19 keratin 19, type I
LARGE like-glycosyltransferase
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP5 low density lipoprotein receptor-related protein 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MASP2 mannan-binding lectin serine peptidase 2
MDC1 mediator of DNA-damage checkpoint 1
MEGF8 multiple EGF-like-domains 8
MGMT O-6-methylguanine-DNA methyltransferase
MIA melanoma inhibitory activity
MIA3 melanoma inhibitory activity family, member 3
MIR126 microRNA 126
MIR127 microRNA 127
MIR142 microRNA 142
MIR155 microRNA 155
MIR17 microRNA 17
MIR21 microRNA 21
MIXL1 Mix paired-like homeobox
MKI67 marker of proliferation Ki-67
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYBPC3 myosin binding protein C, cardiac
NANOG Nanog homeobox
NES nestin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NODAL nodal growth differentiation factor
NOTCH4 notch 4
NPTX1 neuronal pentraxin I
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ORAI1 ORAI calcium release-activated calcium modulator 1
PAEP progestagen-associated endometrial protein
PARK7 parkinson protein 7
PAX5 paired box 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PDPN podoplanin
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAU plasminogen activator, urokinase
PPARA peroxisome proliferator-activated receptor alpha
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PRKD1 protein kinase D1
PTK7 protein tyrosine kinase 7 (inactive)
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RHOA ras homolog family member A
RHOH ras homolog family member H
RUNX3 runt-related transcription factor 3
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SDC1 syndecan 1
SELE selectin E
SELPLG selectin P ligand
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHOX2 short stature homeobox 2
SIPA1 signal-induced proliferation-associated 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SOCS3 suppressor of cytokine signaling 3
SOST sclerostin
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX21 T-box 21
TDGF1 teratocarcinoma-derived growth factor 1
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRIM33 tripartite motif containing 33
TRIM8 tripartite motif containing 8
TTC8 tetratricopeptide repeat domain 8
TUFM Tu translation elongation factor, mitochondrial
TYMS thymidylate synthetase
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
WIF1 WNT inhibitory factor 1