nomifensine-2224 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the nomifensine-2224 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
AIRE autoimmune regulator
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPTL4 angiopoietin-like 4
ARID4B AT rich interactive domain 4B (RBP1-like)
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BMP8A bone morphogenetic protein 8a
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BST2 bone marrow stromal cell antigen 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF1 chromosome 11 open reading frame 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CATSPERB catsper channel auxiliary subunit beta
CCNK cyclin K
CD7 CD7 molecule
CD70 CD70 molecule
CDC42 cell division cycle 42
CDHR2 cadherin-related family member 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CNN1 calponin 1, basic, smooth muscle
CTNS cystinosin, lysosomal cystine transporter
DFNB31 deafness, autosomal recessive 31
DLC1 DLC1 Rho GTPase activating protein
EPX eosinophil peroxidase
F9 coagulation factor IX
FBXO4 F-box protein 4
FHL1 four and a half LIM domains 1
GK3P glycerol kinase 3 pseudogene
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GSTP1 glutathione S-transferase pi 1
HIPK3 homeodomain interacting protein kinase 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSF2BP heat shock transcription factor 2 binding protein
HSF4 heat shock transcription factor 4
ICAM1 intercellular adhesion molecule 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL6ST interleukin 6 signal transducer
INHBE inhibin, beta E
IZUMO4 IZUMO family member 4
KIF25-AS1 KIF25 antisense RNA 1
KLF13 Kruppel-like factor 13
KRT75 keratin 75, type II
LCMT2 leucine carboxyl methyltransferase 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN2A2 mannosidase, alpha, class 2A, member 2
MBNL2 muscleblind-like splicing regulator 2
MEGF9 multiple EGF-like-domains 9
MINK1 misshapen-like kinase 1
MIP major intrinsic protein of lens fiber
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L1 NEDD4 binding protein 2-like 1
NCR1 natural cytotoxicity triggering receptor 1
NF2 neurofibromin 2 (merlin)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIB nuclear factor I/B
NNMT nicotinamide N-methyltransferase
NUPR1 nuclear protein, transcriptional regulator, 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCDH1 protocadherin 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PHC3 polyhomeotic homolog 3 (Drosophila)
PKP2 plakophilin 2
PLXNB3 plexin B3
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PRB4 proline-rich protein BstNI subfamily 4
QKI QKI, KH domain containing, RNA binding
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SKIL SKI-like proto-oncogene
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOAT2 sterol O-acyltransferase 2
SPDEF SAM pointed domain containing ETS transcription factor
SPEG SPEG complex locus
SPRED2 sprouty-related, EVH1 domain containing 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD8 StAR-related lipid transfer (START) domain containing 8
STK24 serine/threonine kinase 24
THAP9 THAP domain containing 9
TNPO2 transportin 2
VCAN versican
WAPAL wings apart-like homolog (Drosophila)
WNK1 WNK lysine deficient protein kinase 1
ZNF235 zinc finger protein 235
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ALS2CL ALS2 C-terminal like
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC4 armadillo repeat containing 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BFSP1 beaded filament structural protein 1, filensin
C17ORF53 chromosome 17 open reading frame 53
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CD34 CD34 molecule
CD82 CD82 molecule
CDKN2AIP CDKN2A interacting protein
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CPTP ceramide-1-phosphate transfer protein
CSF1R colony stimulating factor 1 receptor
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
DSPP dentin sialophosphoprotein
DYSF dysferlin
EFHD2 EF-hand domain family, member D2
EPHA2 EPH receptor A2
ETNK2 ethanolamine kinase 2
EVA1B eva-1 homolog B (C. elegans)
FAM189A2 family with sequence similarity 189, member A2
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FBXO46 F-box protein 46
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRC5D G protein-coupled receptor, class C, group 5, member D
GYS1 glycogen synthase 1 (muscle)
HDAC5 histone deacetylase 5
HIST1H4A histone cluster 1, H4a
HMOX1 heme oxygenase 1
HSPA1L heat shock 70kDa protein 1-like
IL12RB1 interleukin 12 receptor, beta 1
IP6K1 inositol hexakisphosphate kinase 1
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0754 KIAA0754
MGC12488
MSI1 musashi RNA-binding protein 1
MST1 macrophage stimulating 1
MTCL1 microtubule crosslinking factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1E myosin IE
NDE1 nudE neurodevelopment protein 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NXPE3 neurexophilin and PC-esterase domain family, member 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD3 OTU deubiquitinase 3
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB8 protocadherin beta 8
PEX26 peroxisomal biogenesis factor 26
PGM1 phosphoglucomutase 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PQLC2 PQ loop repeat containing 2
PRR3 proline rich 3
RAB32 RAB32, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF208 ring finger protein 208
RPAP1 RNA polymerase II associated protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX3 SRY (sex determining region Y)-box 3
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STMN3 stathmin-like 3
SYBU syntabulin (syntaxin-interacting)
SYNC syncoilin, intermediate filament protein
TEAD3 TEA domain family member 3
TRPC5 transient receptor potential cation channel, subfamily C, member 5
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZNF134 zinc finger protein 134
ZNF37BP zinc finger protein 37B, pseudogene
ZNF696 zinc finger protein 696
ZSCAN2 zinc finger and SCAN domain containing 2