Symbol |
Name |
Standardized Value |
PRKDC
|
protein kinase, DNA-activated, catalytic polypeptide
|
3.6597
|
XRCC4
|
X-ray repair complementing defective repair in Chinese hamster cells 4
|
3.3645
|
XRCC6
|
X-ray repair complementing defective repair in Chinese hamster cells 6
|
3.22045
|
LIG4
|
ligase IV, DNA, ATP-dependent
|
3.17646
|
ATM
|
ATM serine/threonine kinase
|
2.30341
|
RAD51
|
RAD51 recombinase
|
2.20818
|
MRE11A
|
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
|
2.09983
|
H2AFX
|
H2A histone family, member X
|
1.92508
|
RAD50
|
RAD50 homolog (S. cerevisiae)
|
1.83815
|
RAD52
|
RAD52 homolog (S. cerevisiae)
|
1.83747
|
DCLRE1C
|
DNA cross-link repair 1C
|
1.78715
|
NHEJ1
|
nonhomologous end-joining factor 1
|
1.77992
|
BRCA1
|
breast cancer 1, early onset
|
1.76432
|
XRCC5
|
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
|
1.68055
|
XRCC2
|
X-ray repair complementing defective repair in Chinese hamster cells 2
|
1.62945
|
XRCC3
|
X-ray repair complementing defective repair in Chinese hamster cells 3
|
1.61412
|
LIG3
|
ligase III, DNA, ATP-dependent
|
1.53331
|
POLM
|
polymerase (DNA directed), mu
|
1.48814
|
BRCA2
|
breast cancer 2, early onset
|
1.44968
|
XRCC1
|
X-ray repair complementing defective repair in Chinese hamster cells 1
|
1.39016
|
AICDA
|
activation-induced cytidine deaminase
|
1.36857
|
SETMAR
|
SET domain and mariner transposase fusion gene
|
1.35649
|
LIG1
|
ligase I, DNA, ATP-dependent
|
1.33467
|
EXO1
|
exonuclease 1
|
1.27505
|
POLL
|
polymerase (DNA directed), lambda
|
1.24865
|
TP53
|
tumor protein p53
|
1.18543
|
ZKSCAN7
|
zinc finger with KRAB and SCAN domains 7
|
1.17311
|
CHEK1
|
checkpoint kinase 1
|
1.13778
|
PARP1
|
poly (ADP-ribose) polymerase 1
|
1.09493
|
RAG1
|
recombination activating gene 1
|
1.08019
|
MDC1
|
mediator of DNA-damage checkpoint 1
|
1.06448
|
APLF
|
aprataxin and PNKP like factor
|
1.0403
|
RAD51C
|
RAD51 paralog C
|
1.02979
|
WRN
|
Werner syndrome, RecQ helicase-like
|
1.02879
|
RAG2
|
recombination activating gene 2
|
0.962627
|
ATR
|
ATR serine/threonine kinase
|
0.909716
|
PPP6R3
|
protein phosphatase 6, regulatory subunit 3
|
0.902281
|
MSH2
|
mutS homolog 2
|
0.897646
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
0.897183
|
RNF168
|
ring finger protein 168, E3 ubiquitin protein ligase
|
0.843318
|
FANCD2
|
Fanconi anemia, complementation group D2
|
0.836433
|
RAD54L
|
RAD54-like (S. cerevisiae)
|
0.825418
|
ERCC4
|
excision repair cross-complementation group 4
|
0.824959
|
XRCC6BP1
|
XRCC6 binding protein 1
|
0.820829
|
NBAS
|
neuroblastoma amplified sequence
|
0.803396
|
RAD18
|
RAD18 E3 ubiquitin protein ligase
|
0.791939
|
DCLRE1A
|
DNA cross-link repair 1A
|
0.777298
|
PPP6R2
|
protein phosphatase 6, regulatory subunit 2
|
0.773188
|
NBN
|
nibrin
|
0.76726
|
HEATR4
|
HEAT repeat containing 4
|
0.751357
|
RAD54B
|
RAD54 homolog B (S. cerevisiae)
|
0.751357
|
CIRBP-AS1
|
CIRBP antisense RNA 1
|
0.751357
|
FAM49A
|
family with sequence similarity 49, member A
|
0.751357
|
DEPDC4
|
DEP domain containing 4
|
0.751357
|
TRIM7
|
tripartite motif containing 7
|
0.751357
|
PLSCR2
|
phospholipid scramblase 2
|
0.751357
|
USP42
|
ubiquitin specific peptidase 42
|
0.751357
|
PSORS1C2
|
psoriasis susceptibility 1 candidate 2
|
0.751357
|
ZBED9
|
zinc finger, BED-type containing 9
|
0.751357
|
ZBED8
|
zinc finger, BED-type containing 8
|
0.751357
|
ATXN7L1
|
ataxin 7-like 1
|
0.751357
|
ERCC1
|
excision repair cross-complementation group 1
|
0.744122
|
FBXO24
|
F-box protein 24
|
0.725705
|
PPP6R1
|
protein phosphatase 6, regulatory subunit 1
|
0.700423
|
MDM2
|
MDM2 proto-oncogene, E3 ubiquitin protein ligase
|
0.694709
|
TP53BP1
|
tumor protein p53 binding protein 1
|
0.69427
|
REV3L
|
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
|
0.67463
|
TERF2
|
telomeric repeat binding factor 2
|
0.666827
|
RAD51AP1
|
RAD51 associated protein 1
|
0.650869
|
ENPP5
|
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
|
0.648291
|
UIMC1
|
ubiquitin interaction motif containing 1
|
0.623504
|
TDP2
|
tyrosyl-DNA phosphodiesterase 2
|
0.622654
|
RNF8
|
ring finger protein 8, E3 ubiquitin protein ligase
|
0.619255
|
ERCC2
|
excision repair cross-complementation group 2
|
0.617557
|
PARP3
|
poly (ADP-ribose) polymerase family, member 3
|
0.613742
|
UBA2
|
ubiquitin-like modifier activating enzyme 2
|
0.613318
|
MSL1
|
male-specific lethal 1 homolog (Drosophila)
|
0.593072
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
0.592652
|
TDP1
|
tyrosyl-DNA phosphodiesterase 1
|
0.592232
|
XRRA1
|
X-ray radiation resistance associated 1
|
0.583431
|
MLH1
|
mutL homolog 1
|
0.582176
|
TOP1
|
topoisomerase (DNA) I
|
0.566754
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
0.558457
|
FBXO28
|
F-box protein 28
|
0.532488
|
BLM
|
Bloom syndrome, RecQ helicase-like
|
0.531668
|
GNG10
|
guanine nucleotide binding protein (G protein), gamma 10
|
0.516124
|
PSORS1C1
|
psoriasis susceptibility 1 candidate 1
|
0.516124
|
BANP
|
BTG3 associated nuclear protein
|
0.502288
|
UNG
|
uracil-DNA glycosylase
|
0.49742
|
PCNA
|
proliferating cell nuclear antigen
|
0.497015
|
SBNO2
|
strawberry notch homolog 2 (Drosophila)
|
0.493775
|
POLD2
|
polymerase (DNA directed), delta 2, accessory subunit
|
0.493775
|
EGFR
|
epidermal growth factor receptor
|
0.487711
|
SETD3
|
SET domain containing 3
|
0.485693
|
PLP1
|
proteolipid protein 1
|
0.484886
|
BMP8A
|
bone morphogenetic protein 8a
|
0.474018
|
UBE2K
|
ubiquitin-conjugating enzyme E2K
|
0.464798
|
H2AFY
|
H2A histone family, member Y
|
0.461998
|
DCAF11
|
DDB1 and CUL4 associated factor 11
|
0.461599
|
OGG1
|
8-oxoguanine DNA glycosylase
|
0.4608
|
HIST1H4B
|
histone cluster 1, H4b
|
0.459602
|
HIST1H4A
|
histone cluster 1, H4a
|
0.459602
|
HIST1H4H
|
histone cluster 1, H4h
|
0.459602
|
HIST1H4I
|
histone cluster 1, H4i
|
0.459602
|
HIST2H4B
|
histone cluster 2, H4b
|
0.459602
|
HIST1H4C
|
histone cluster 1, H4c
|
0.459602
|
HIST1H4J
|
histone cluster 1, H4j
|
0.459602
|
HIST2H4A
|
histone cluster 2, H4a
|
0.459602
|
HIST1H4K
|
histone cluster 1, H4k
|
0.459602
|
HIST1H4E
|
histone cluster 1, H4e
|
0.459602
|
HIST1H4D
|
histone cluster 1, H4d
|
0.459602
|
HIST1H4F
|
histone cluster 1, H4f
|
0.459203
|
HIST1H4L
|
histone cluster 1, H4l
|
0.459203
|
HIST4H4
|
histone cluster 4, H4
|
0.459203
|
SMG1
|
SMG1 phosphatidylinositol 3-kinase-related kinase
|
0.454418
|
POLQ
|
polymerase (DNA directed), theta
|
0.450438
|
BCR
|
breakpoint cluster region
|
0.448451
|
PARP4
|
poly (ADP-ribose) polymerase family, member 4
|
0.438542
|
RNF169
|
ring finger protein 169
|
0.434196
|
RAB9B
|
RAB9B, member RAS oncogene family
|
0.429859
|
RNF144A
|
ring finger protein 144A
|
0.425138
|
FEN1
|
flap structure-specific endonuclease 1
|
0.424745
|
HIST1H2AD
|
histone cluster 1, H2ad
|
0.421997
|
HIST1H2AM
|
histone cluster 1, H2am
|
0.421997
|
HIST1H2AJ
|
histone cluster 1, H2aj
|
0.421997
|
H2AFJ
|
H2A histone family, member J
|
0.421997
|
HIST1H2AH
|
histone cluster 1, H2ah
|
0.421604
|
HIST1H2AG
|
histone cluster 1, H2ag
|
0.420428
|
H2AFY2
|
H2A histone family, member Y2
|
0.41886
|
HIST1H2AB
|
histone cluster 1, H2ab
|
0.418077
|
HIST1H2AE
|
histone cluster 1, H2ae
|
0.418077
|
H2AFV
|
H2A histone family, member V
|
0.417685
|
H2AFB1
|
H2A histone family, member B1
|
0.414946
|
H2AFB2
|
H2A histone family, member B2
|
0.41143
|
POT1
|
protection of telomeres 1
|
0.398975
|
CELA3A
|
chymotrypsin-like elastase family, member 3A
|
0.394323
|
ZNF461
|
zinc finger protein 461
|
0.392775
|
TOP2B
|
topoisomerase (DNA) II beta 180kDa
|
0.391615
|
C6ORF15
|
chromosome 6 open reading frame 15
|
0.390455
|
DNASE2
|
deoxyribonuclease II, lysosomal
|
0.387751
|
BARD1
|
BRCA1 associated RING domain 1
|
0.385051
|
TCF19
|
transcription factor 19
|
0.378891
|
TEP1
|
telomerase-associated protein 1
|
0.377354
|
DNTT
|
DNA nucleotidylexotransferase
|
0.372366
|
ERCC5
|
excision repair cross-complementation group 5
|
0.368919
|
RAD51B
|
RAD51 paralog B
|
0.368536
|
FANCA
|
Fanconi anemia, complementation group A
|
0.368153
|
TRIM4
|
tripartite motif containing 4
|
0.364713
|
CCNA2
|
cyclin A2
|
0.364331
|
RBBP8
|
retinoblastoma binding protein 8
|
0.360515
|
MSH4
|
mutS homolog 4
|
0.354042
|
HIST3H2BB
|
histone cluster 3, H2bb
|
0.346829
|
HIST2H2BF
|
histone cluster 2, H2bf
|
0.346829
|
HIST1H2BH
|
histone cluster 1, H2bh
|
0.346829
|
HIST1H2BD
|
histone cluster 1, H2bd
|
0.346829
|
HIST1H2BF
|
histone cluster 1, H2bf
|
0.345314
|
HIST1H2BC
|
histone cluster 1, H2bc
|
0.345314
|
HIST1H2BA
|
histone cluster 1, H2ba
|
0.344178
|
BRIP1
|
BRCA1 interacting protein C-terminal helicase 1
|
0.340773
|
SMARCA5
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
|
0.340017
|
AUTS2
|
autism susceptibility candidate 2
|
0.339261
|
MSH6
|
mutS homolog 6
|
0.335487
|
PARK2
|
parkin RBR E3 ubiquitin protein ligase
|
0.334356
|
XPA
|
xeroderma pigmentosum, complementation group A
|
0.329084
|
NPAP1
|
nuclear pore associated protein 1
|
0.327205
|
APTX
|
aprataxin
|
0.326078
|
TSN
|
translin
|
0.324951
|
RAB11FIP5
|
RAB11 family interacting protein 5 (class I)
|
0.324201
|
CCHCR1
|
coiled-coil alpha-helical rod protein 1
|
0.32345
|
FER
|
fer (fps/fes related) tyrosine kinase
|
0.321575
|
HOXD13
|
homeobox D13
|
0.318953
|
CHEK2
|
checkpoint kinase 2
|
0.317456
|
APEX1
|
APEX nuclease (multifunctional DNA repair enzyme) 1
|
0.317456
|
FLT3
|
fms-related tyrosine kinase 3
|
0.308494
|
GMCL1
|
germ cell-less, spermatogenesis associated 1
|
0.303283
|
PAPD7
|
PAP associated domain containing 7
|
0.301425
|
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
|
0.29994
|
HUS1
|
HUS1 checkpoint homolog (S. pombe)
|
0.295119
|
MEIG1
|
meiosis/spermiogenesis associated 1
|
0.290308
|
NEIL1
|
nei endonuclease VIII-like 1 (E. coli)
|
0.287721
|
SUB1
|
SUB1 homolog (S. cerevisiae)
|
0.287352
|
VCX3B
|
variable charge, X-linked 3B
|
0.281453
|
VCX2
|
variable charge, X-linked 2
|
0.281453
|
VCX
|
variable charge, X-linked
|
0.281453
|
ATP5D
|
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
|
0.278509
|
PRKRA
|
protein kinase, interferon-inducible double stranded RNA dependent activator
|
0.272633
|
MSH5
|
mutS homolog 5
|
0.270068
|
XPC
|
xeroderma pigmentosum, complementation group C
|
0.267505
|
SMARCC1
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
|
0.266408
|
TERF1
|
telomeric repeat binding factor (NIMA-interacting) 1
|
0.262025
|
BCKDHB
|
branched chain keto acid dehydrogenase E1, beta polypeptide
|
0.26166
|
SMC6
|
structural maintenance of chromosomes 6
|
0.260931
|
HIST2H3PS2
|
histone cluster 2, H3, pseudogene 2
|
0.251114
|
PMS2
|
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
|
0.249664
|
NUFIP1
|
nuclear fragile X mental retardation protein interacting protein 1
|
0.249664
|
UBE2V2
|
ubiquitin-conjugating enzyme E2 variant 2
|
0.249302
|
H3F3A
|
H3 histone, family 3A
|
0.247854
|
H3F3B
|
H3 histone, family 3B (H3.3B)
|
0.247854
|
TFIP11
|
tuftelin interacting protein 11
|
0.247854
|
VCX3A
|
variable charge, X-linked 3A
|
0.24713
|
NIT2
|
nitrilase family, member 2
|
0.243879
|
SLC35C1
|
solute carrier family 35 (GDP-fucose transporter), member C1
|
0.243158
|
FBXL19
|
F-box and leucine-rich repeat protein 19
|
0.242797
|
FANCC
|
Fanconi anemia, complementation group C
|
0.242797
|
CCNA1
|
cyclin A1
|
0.238478
|
TRIM3
|
tripartite motif containing 3
|
0.23776
|
MIDN
|
midnolin
|
0.233459
|
HDAC9
|
histone deacetylase 9
|
0.229888
|
HIST2H2AC
|
histone cluster 2, H2ac
|
0.229176
|
HIST2H2AA3
|
histone cluster 2, H2aa3
|
0.228819
|
HIST2H2AA4
|
histone cluster 2, H2aa4
|
0.228819
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
0.225622
|
SETD8
|
SET domain containing (lysine methyltransferase) 8
|
0.225267
|
DNMT3B
|
DNA (cytosine-5-)-methyltransferase 3 beta
|
0.222436
|
ASXL1
|
additional sex combs like transcriptional regulator 1
|
0.219617
|
MVP
|
major vault protein
|
0.218212
|
PSMC3IP
|
PSMC3 interacting protein
|
0.217861
|
SMARCC2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
|
0.217861
|
UBE2N
|
ubiquitin-conjugating enzyme E2N
|
0.216111
|
KDM4D
|
lysine (K)-specific demethylase 4D
|
0.214366
|
PRKAA2
|
protein kinase, AMP-activated, alpha 2 catalytic subunit
|
0.213322
|
RING1
|
ring finger protein 1
|
0.213322
|
PTCH1
|
patched 1
|
0.212627
|
MIR100
|
microRNA 100
|
0.211933
|
NONO
|
non-POU domain containing, octamer-binding
|
0.211587
|
CDK2
|
cyclin-dependent kinase 2
|
0.209858
|
PRKY
|
protein kinase, Y-linked, pseudogene
|
0.208137
|
PRKX
|
protein kinase, X-linked
|
0.207794
|
NRAS
|
neuroblastoma RAS viral (v-ras) oncogene homolog
|
0.206082
|
CCNO
|
cyclin O
|
0.206082
|
ISPD
|
isoprenoid synthase domain containing
|
0.205059
|
RAD9A
|
RAD9 homolog A (S. pombe)
|
0.204039
|
AVEN
|
apoptosis, caspase activation inhibitor
|
0.201672
|
ZNF350
|
zinc finger protein 350
|
0.198658
|
EYA4
|
EYA transcriptional coactivator and phosphatase 4
|
0.198658
|
WDR48
|
WD repeat domain 48
|
0.195025
|
IARS
|
isoleucyl-tRNA synthetase
|
0.192423
|
GRHL1
|
grainyhead-like 1 (Drosophila)
|
0.1921
|
PPP1R12C
|
protein phosphatase 1, regulatory subunit 12C
|
0.1921
|
NEIL2
|
nei endonuclease VIII-like 2 (E. coli)
|
0.189539
|
ERCC3
|
excision repair cross-complementation group 3
|
0.18702
|
PSMD14
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
|
0.18702
|
KAT5
|
K(lysine) acetyltransferase 5
|
0.184853
|
TENM4
|
teneurin transmembrane protein 4
|
0.182422
|
RNF40
|
ring finger protein 40, E3 ubiquitin protein ligase
|
0.179459
|
SPO11
|
SPO11 meiotic protein covalently bound to DSB
|
0.175466
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
0.175188
|
UVRAG
|
UV radiation resistance associated
|
0.174911
|
IGF1R
|
insulin-like growth factor 1 receptor
|
0.173814
|
TREX2
|
three prime repair exonuclease 2
|
0.170888
|
RECQL4
|
RecQ protein-like 4
|
0.165463
|
RAD23B
|
RAD23 homolog B (S. cerevisiae)
|
0.165
|
TRIM28
|
tripartite motif containing 28
|
0.163865
|
PPP4R2
|
protein phosphatase 4, regulatory subunit 2
|
0.163865
|
PPP4C
|
protein phosphatase 4, catalytic subunit
|
0.16342
|
RNF4
|
ring finger protein 4
|
0.16233
|
TRIP13
|
thyroid hormone receptor interactor 13
|
0.16233
|
PMP22
|
peripheral myelin protein 22
|
0.160863
|
PIF1
|
PIF1 5'-to-3' DNA helicase
|
0.159462
|
BCCIP
|
BRCA2 and CDKN1A interacting protein
|
0.159074
|
FIP1L1
|
factor interacting with PAPOLA and CPSF1
|
0.158882
|