nordihydroguaiaretic acid-1003 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the nordihydroguaiaretic acid-1003 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
ADAP1 ArfGAP with dual PH domains 1
AKR1C1 aldo-keto reductase family 1, member C1
ALOX5 arachidonate 5-lipoxygenase
ALPK1 alpha-kinase 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ARMCX4 armadillo repeat containing, X-linked 4
ATP11A ATPase, class VI, type 11A
BBS9 Bardet-Biedl syndrome 9
BHLHE40 basic helix-loop-helix family, member e40
BMP2K BMP2 inducible kinase
BTF3P12 basic transcription factor 3 pseudogene 12
BTN2A2 butyrophilin, subfamily 2, member A2
CCKAR cholecystokinin A receptor
CDC14B cell division cycle 14B
CDH8 cadherin 8, type 2
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CFD complement factor D (adipsin)
CLCN5 chloride channel, voltage-sensitive 5
CORT cortistatin
CXCL8 chemokine (C-X-C motif) ligand 8
DZANK1 double zinc ribbon and ankyrin repeat domains 1
FAM174B family with sequence similarity 174, member B
FBXL2 F-box and leucine-rich repeat protein 2
FHL1 four and a half LIM domains 1
FOSL2 FOS-like antigen 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUK1 guanylate kinase 1
HHLA3 HERV-H LTR-associating 3
HIPK2 homeodomain interacting protein kinase 2
HK2 hexokinase 2
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOXB7 homeobox B7
IGFBP5 insulin-like growth factor binding protein 5
IQSEC2 IQ motif and Sec7 domain 2
KIAA0319L KIAA0319-like
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTC4S leukotriene C4 synthase
MTMR3 myotubularin related protein 3
MYO1E myosin IE
MZF1 myeloid zinc finger 1
NEBL nebulette
NIPAL2 NIPA-like domain containing 2
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARVB parvin, beta
PDE4DIP phosphodiesterase 4D interacting protein
PEX5 peroxisomal biogenesis factor 5
PLCE1 phospholipase C, epsilon 1
PLD2 phospholipase D2
PLXNA1 plexin A1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PSEN2 presenilin 2
PTGES prostaglandin E synthase
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVR poliovirus receptor
RGS12 regulator of G-protein signaling 12
RPS3A ribosomal protein S3A
RTN2 reticulon 2
SBNO2 strawberry notch homolog 2 (Drosophila)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3BP2 SH3-domain binding protein 2
SIX3 SIX homeobox 3
SLAMF7 SLAM family member 7
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPAG8 sperm associated antigen 8
SPRR1A small proline-rich protein 1A
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSX1 synovial sarcoma, X breakpoint 1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STC1 stanniocalcin 1
TBC1D2B TBC1 domain family, member 2B
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TFPI2 tissue factor pathway inhibitor 2
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TROVE2 TROVE domain family, member 2
TSPYL2 TSPY-like 2
TTBK2 tau tubulin kinase 2
TTC33 tetratricopeptide repeat domain 33
UBE3A ubiquitin protein ligase E3A
USP27X ubiquitin specific peptidase 27, X-linked
USP36 ubiquitin specific peptidase 36
VAX2 ventral anterior homeobox 2
VEGFA vascular endothelial growth factor A
VIPR2 vasoactive intestinal peptide receptor 2
WDTC1 WD and tetratricopeptide repeats 1
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADM adrenomedullin
BBC3 BCL2 binding component 3
BCCIP BRCA2 and CDKN1A interacting protein
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CD151 CD151 molecule (Raph blood group)
CHML choroideremia-like (Rab escort protein 2)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CISH cytokine inducible SH2-containing protein
CRABP1 cellular retinoic acid binding protein 1
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DGKE diacylglycerol kinase, epsilon 64kDa
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
ECHDC3 enoyl CoA hydratase domain containing 3
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERF Ets2 repressor factor
ESRP2 epithelial splicing regulatory protein 2
ETAA1 Ewing tumor-associated antigen 1
FBXL4 F-box and leucine-rich repeat protein 4
FBXW12 F-box and WD repeat domain containing 12
FER fer (fps/fes related) tyrosine kinase
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMEB1 glucocorticoid modulatory element binding protein 1
GRTP1 growth hormone regulated TBC protein 1
HAUS6 HAUS augmin-like complex, subunit 6
HDAC4 histone deacetylase 4
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFT81 intraflagellar transport 81
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
KIAA0556 KIAA0556
LINC00115 long intergenic non-protein coding RNA 115
LRRC61 leucine rich repeat containing 61
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFSD11 major facilitator superfamily domain containing 11
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDE1 nudE neurodevelopment protein 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PARD6A par-6 family cell polarity regulator alpha
PCDHA6 protocadherin alpha 6
PDLIM2 PDZ and LIM domain 2 (mystique)
PGAP1 post-GPI attachment to proteins 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G10 phospholipase A2, group X
PODXL2 podocalyxin-like 2
PPAN peter pan homolog (Drosophila)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRMT7 protein arginine methyltransferase 7
PRR7 proline rich 7 (synaptic)
PTPRU protein tyrosine phosphatase, receptor type, U
PVRL3 poliovirus receptor-related 3
PYCRL pyrroline-5-carboxylate reductase-like
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFTN1 raftlin, lipid raft linker 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPAP1 RNA polymerase II associated protein 1
SCAI suppressor of cancer cell invasion
SGMS1 sphingomyelin synthase 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX15 sorting nexin 15
SPINK4 serine peptidase inhibitor, Kazal type 4
SYCP2 synaptonemal complex protein 2
TRIM5 tripartite motif containing 5
TTC23 tetratricopeptide repeat domain 23
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
XKR8 XK, Kell blood group complex subunit-related family, member 8
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB24 zinc finger and BTB domain containing 24
ZNF324 zinc finger protein 324
ZNF35 zinc finger protein 35
ZNF492 zinc finger protein 492
ZNF586 zinc finger protein 586
ZNF787 zinc finger protein 787
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZSCAN26 zinc finger and SCAN domain containing 26