nordihydroguaiaretic acid-1061 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the nordihydroguaiaretic acid-1061 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AKR1C3 aldo-keto reductase family 1, member C3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARMCX1 armadillo repeat containing, X-linked 1
ARRB1 arrestin, beta 1
ASPH aspartate beta-hydroxylase
ATF3 activating transcription factor 3
BCL2L1 BCL2-like 1
CD24 CD24 molecule
CDC14B cell division cycle 14B
CEP76 centrosomal protein 76kDa
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLN3 ceroid-lipofuscinosis, neuronal 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CRYL1 crystallin, lambda 1
CSNK1E casein kinase 1, epsilon
DIDO1 death inducer-obliterator 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF5A2 eukaryotic translation initiation factor 5A2
EML3 echinoderm microtubule associated protein like 3
FADS1 fatty acid desaturase 1
FADS3 fatty acid desaturase 3
FAM49B family with sequence similarity 49, member B
FLJ42627 uncharacterized LOC645644
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45B growth arrest and DNA-damage-inducible, beta
GALK2 galactokinase 2
GLB1L2 galactosidase, beta 1-like 2
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HLA-F major histocompatibility complex, class I, F
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFRD1 interferon-related developmental regulator 1
IL4R interleukin 4 receptor
INSIG1 insulin induced gene 1
IRF5 interferon regulatory factor 5
JUN jun proto-oncogene
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM4A lysine (K)-specific demethylase 4A
KLF6 Kruppel-like factor 6
LMAN1 lectin, mannose-binding, 1
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MANF mesencephalic astrocyte-derived neurotrophic factor
MPPE1 metallophosphoesterase 1
MPZL1 myelin protein zero-like 1
MSMO1 methylsterol monooxygenase 1
MT1F metallothionein 1F
MZF1 myeloid zinc finger 1
NDRG4 NDRG family member 4
NFYA nuclear transcription factor Y, alpha
NUMB numb homolog (Drosophila)
PELO pelota homolog (Drosophila)
PLD3 phospholipase D family, member 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POT1 protection of telomeres 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB28 RAB28, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGDS ral guanine nucleotide dissociation stimulator
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RNF126 ring finger protein 126
RNF31 ring finger protein 31
RUFY3 RUN and FYVE domain containing 3
RUNX1 runt-related transcription factor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SEC63 SEC63 homolog (S. cerevisiae)
SKIL SKI-like proto-oncogene
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMCO4 single-pass membrane protein with coiled-coil domains 4
SP100 SP100 nuclear antigen
ST7 suppression of tumorigenicity 7
STX2 syntaxin 2
TBC1D31 TBC1 domain family, member 31
TELO2 telomere maintenance 2
TMEM57 transmembrane protein 57
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIM62 tripartite motif containing 62
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
UHRF1BP1L UHRF1 binding protein 1-like
USP34 ubiquitin specific peptidase 34
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAMP4 vesicle-associated membrane protein 4
ZMYM2 zinc finger, MYM-type 2
ZNF133 zinc finger protein 133
ZNF174 zinc finger protein 174

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGO1 argonaute RISC catalytic component 1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ARRB2 arrestin, beta 2
ATP13A2 ATPase type 13A2
AXIN1 axin 1
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCAR3 breast cancer anti-estrogen resistance 3
BIK BCL2-interacting killer (apoptosis-inducing)
C1ORF109 chromosome 1 open reading frame 109
C1ORF216 chromosome 1 open reading frame 216
C4ORF19 chromosome 4 open reading frame 19
CBR4 carbonyl reductase 4
CEP72 centrosomal protein 72kDa
CRCP CGRP receptor component
DBR1 debranching RNA lariats 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
E2F8 E2F transcription factor 8
EMD emerin
EPN3 epsin 3
FAM155B family with sequence similarity 155, member B
FAM188A family with sequence similarity 188, member A
FBXO46 F-box protein 46
FPGS folylpolyglutamate synthase
GCA grancalcin, EF-hand calcium binding protein
GRB14 growth factor receptor-bound protein 14
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HAUS3 HAUS augmin-like complex, subunit 3
IREB2 iron-responsive element binding protein 2
JADE3 jade family PHD finger 3
KATNBL1 katanin p80 subunit B-like 1
KLC2 kinesin light chain 2
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MEIS3P1 Meis homeobox 3 pseudogene 1
MFSD12 major facilitator superfamily domain containing 12
MIS18BP1 MIS18 binding protein 1
MISP mitotic spindle positioning
MNT MAX network transcriptional repressor
MPI mannose phosphate isomerase
MRPL2 mitochondrial ribosomal protein L2
MT1H metallothionein 1H
MTCL1 microtubule crosslinking factor 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOTCH1 notch 1
NUBPL nucleotide binding protein-like
NUP62CL nucleoporin 62kDa C-terminal like
NXN nucleoredoxin
PARG poly (ADP-ribose) glycohydrolase
PBLD phenazine biosynthesis-like protein domain containing
PCNXL4 pecanex-like 4 (Drosophila)
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDZRN3 PDZ domain containing ring finger 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRKCD protein kinase C, delta
PRR7 proline rich 7 (synaptic)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
REEP4 receptor accessory protein 4
RNF167 ring finger protein 167
RNF25 ring finger protein 25
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SAV1 salvador family WW domain containing protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCPEP1 serine carboxypeptidase 1
SHCBP1 SHC SH2-domain binding protein 1
SPATA7 spermatogenesis associated 7
SPHK1 sphingosine kinase 1
SSFA2 sperm specific antigen 2
STK25 serine/threonine kinase 25
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TGS1 trimethylguanosine synthase 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TPRA1 transmembrane protein, adipocyte asscociated 1
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC2 trafficking protein particle complex 2
TRIM13 tripartite motif containing 13
TRIM32 tripartite motif containing 32
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UEVLD UEV and lactate/malate dehyrogenase domains
USP6 ubiquitin specific peptidase 6
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDR47 WD repeat domain 47
ZMAT5 zinc finger, matrin-type 5
ZNF212 zinc finger protein 212
ZNF254 zinc finger protein 254
ZNF408 zinc finger protein 408