Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the nordihydroguaiaretic acid-1164 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACACB | acetyl-CoA carboxylase beta |
ACOX1 | acyl-CoA oxidase 1, palmitoyl |
ADGRE1 | adhesion G protein-coupled receptor E1 |
AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
AKAP10 | A kinase (PRKA) anchor protein 10 |
ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
ALOX12 | arachidonate 12-lipoxygenase |
ALPPL2 | alkaline phosphatase, placental-like 2 |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
ATF6B | activating transcription factor 6 beta |
ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
BACE1 | beta-site APP-cleaving enzyme 1 |
BLZF1 | basic leucine zipper nuclear factor 1 |
BTG2 | BTG family, member 2 |
C19ORF66 | chromosome 19 open reading frame 66 |
C5ORF45 | chromosome 5 open reading frame 45 |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
CCT8 | chaperonin containing TCP1, subunit 8 (theta) |
CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
COMMD4 | COMM domain containing 4 |
CPVL | carboxypeptidase, vitellogenic-like |
CTSZ | cathepsin Z |
DCAKD | dephospho-CoA kinase domain containing |
DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DNASE2 | deoxyribonuclease II, lysosomal |
ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
FBXO2 | F-box protein 2 |
FCAR | Fc fragment of IgA receptor |
FKBP8 | FK506 binding protein 8, 38kDa |
FOXC1 | forkhead box C1 |
GK | glycerol kinase |
H2AFX | H2A histone family, member X |
HEMK1 | HemK methyltransferase family member 1 |
HOXC8 | homeobox C8 |
IGHMBP2 | immunoglobulin mu binding protein 2 |
IGL | immunoglobulin lambda locus |
ISG20 | interferon stimulated exonuclease gene 20kDa |
JUND | jun D proto-oncogene |
KIAA0087 | KIAA0087 |
KIAA0319L | KIAA0319-like |
KLF6 | Kruppel-like factor 6 |
KSR1 | kinase suppressor of ras 1 |
LMF2 | lipase maturation factor 2 |
LPPR2 | lipid phosphate phosphatase-related protein type 2 |
MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
MMP25 | matrix metallopeptidase 25 |
NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
NF2 | neurofibromin 2 (merlin) |
NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
NPR2 | natriuretic peptide receptor 2 |
NRP1 | neuropilin 1 |
OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
PAOX | polyamine oxidase (exo-N4-amino) |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PLCD1 | phospholipase C, delta 1 |
PLK3 | polo-like kinase 3 |
PLK4 | polo-like kinase 4 |
PNPLA4 | patatin-like phospholipase domain containing 4 |
POLG | polymerase (DNA directed), gamma |
PVR | poliovirus receptor |
PYGB | phosphorylase, glycogen; brain |
RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 |
RCAN3 | RCAN family member 3 |
RPL10 | ribosomal protein L10 |
SENP5 | SUMO1/sentrin specific peptidase 5 |
SHB | Src homology 2 domain containing adaptor protein B |
SHOX2 | short stature homeobox 2 |
SLC12A9 | solute carrier family 12, member 9 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SMA4 | glucuronidase, beta pseudogene |
SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
SOS2 | son of sevenless homolog 2 (Drosophila) |
SPAG1 | sperm associated antigen 1 |
SPTB | spectrin, beta, erythrocytic |
SSBP3 | single stranded DNA binding protein 3 |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
STRN | striatin, calmodulin binding protein |
SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
TMEM231 | transmembrane protein 231 |
TNS1 | tensin 1 |
TRAF1 | TNF receptor-associated factor 1 |
UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
UTRN | utrophin |
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
ZNF254 | zinc finger protein 254 |
ZNF688 | zinc finger protein 688 |
Symbol | Name |
---|---|
ADAP2 | ArfGAP with dual PH domains 2 |
ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
ARHGAP10 | Rho GTPase activating protein 10 |
ARHGAP4 | Rho GTPase activating protein 4 |
ASB7 | ankyrin repeat and SOCS box containing 7 |
ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
B3GNT1 | |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BAMBI | BMP and activin membrane-bound inhibitor |
BBS10 | Bardet-Biedl syndrome 10 |
CALCOCO1 | calcium binding and coiled-coil domain 1 |
CAPN15 | calpain 15 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CGRRF1 | cell growth regulator with ring finger domain 1 |
CHML | choroideremia-like (Rab escort protein 2) |
CHST10 | carbohydrate sulfotransferase 10 |
CLEC4E | C-type lectin domain family 4, member E |
CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
CXCL2 | chemokine (C-X-C motif) ligand 2 |
DBF4B | DBF4 zinc finger B |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
DENND1C | DENN/MADD domain containing 1C |
DGAT1 | diacylglycerol O-acyltransferase 1 |
DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
DVL1 | dishevelled segment polarity protein 1 |
ELP6 | elongator acetyltransferase complex subunit 6 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
ETV4 | ets variant 4 |
FAM114A2 | family with sequence similarity 114, member A2 |
FAM50B | family with sequence similarity 50, member B |
FANCF | Fanconi anemia, complementation group F |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FGGY | FGGY carbohydrate kinase domain containing |
GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
GPALPP1 | GPALPP motifs containing 1 |
GPR27 | G protein-coupled receptor 27 |
GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
KIF13B | kinesin family member 13B |
KLHDC4 | kelch domain containing 4 |
LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
LMBR1L | limb development membrane protein 1-like |
MACROD1 | MACRO domain containing 1 |
MAP7D3 | MAP7 domain containing 3 |
MBTD1 | mbt domain containing 1 |
MICALL1 | MICAL-like 1 |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
MX2 | MX dynamin-like GTPase 2 |
MYBBP1A | MYB binding protein (P160) 1a |
MYL5 | myosin, light chain 5, regulatory |
NFRKB | nuclear factor related to kappaB binding protein |
NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
NPIPB15 | nuclear pore complex interacting protein family, member B15 |
NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
PAQR4 | progestin and adipoQ receptor family member IV |
PHKG2 | phosphorylase kinase, gamma 2 (testis) |
PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
PRAF2 | PRA1 domain family, member 2 |
PTGES2 | prostaglandin E synthase 2 |
RBM38 | RNA binding motif protein 38 |
REEP4 | receptor accessory protein 4 |
RNF121 | ring finger protein 121 |
S100A12 | S100 calcium binding protein A12 |
SASH3 | SAM and SH3 domain containing 3 |
SCRIB | scribbled planar cell polarity protein |
SIPA1 | signal-induced proliferation-associated 1 |
SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
SLC38A6 | solute carrier family 38, member 6 |
SNHG20 | small nucleolar RNA host gene 20 |
SNHG3 | small nucleolar RNA host gene 3 |
SRD5A3 | steroid 5 alpha-reductase 3 |
ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
TERT | telomerase reverse transcriptase |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TSPYL2 | TSPY-like 2 |
TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
TTC26 | tetratricopeptide repeat domain 26 |
TTF2 | transcription termination factor, RNA polymerase II |
UBP1 | upstream binding protein 1 (LBP-1a) |
URGCP | upregulator of cell proliferation |
XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
XYLT2 | xylosyltransferase II |
ZBTB44 | zinc finger and BTB domain containing 44 |
ZMAT5 | zinc finger, matrin-type 5 |
ZNF14 | zinc finger protein 14 |
ZNF282 | zinc finger protein 282 |
ZNF37BP | zinc finger protein 37B, pseudogene |
ZNF528 | zinc finger protein 528 |
ZNF529 | zinc finger protein 529 |
ZNF665 | zinc finger protein 665 |
ZNF747 | zinc finger protein 747 |