nordihydroguaiaretic acid-1223 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the nordihydroguaiaretic acid-1223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD3 abhydrolase domain containing 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADK adenosine kinase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AZI2 5-azacytidine induced 2
BAX BCL2-associated X protein
BLZF1 basic leucine zipper nuclear factor 1
BMP2K BMP2 inducible kinase
C1S complement component 1, s subcomponent
C9ORF156 chromosome 9 open reading frame 156
C9ORF40 chromosome 9 open reading frame 40
CALR calreticulin
CCNJ cyclin J
COPS8 COP9 signalosome subunit 8
CRELD1 cysteine-rich with EGF-like domains 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
DAZAP2 DAZ associated protein 2
DDIT3 DNA-damage-inducible transcript 3
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHODH dihydroorotate dehydrogenase (quinone)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAH3 dynein, axonemal, heavy chain 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DTWD1 DTW domain containing 1
EID1 EP300 interacting inhibitor of differentiation 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERAP1 endoplasmic reticulum aminopeptidase 1
ERO1L ERO1-like (S. cerevisiae)
ESRRA estrogen-related receptor alpha
FADS2 fatty acid desaturase 2
FAM174B family with sequence similarity 174, member B
FAS Fas cell surface death receptor
FGF2 fibroblast growth factor 2 (basic)
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRX glutaredoxin (thioltransferase)
GOSR2 golgi SNAP receptor complex member 2
HAPLN1 hyaluronan and proteoglycan link protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
INO80B INO80 complex subunit B
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM4A lysine (K)-specific demethylase 4A
KDM7A lysine (K)-specific demethylase 7A
KLF5 Kruppel-like factor 5 (intestinal)
LOX lysyl oxidase
MAP9 microtubule-associated protein 9
MARS methionyl-tRNA synthetase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOX1 NADPH oxidase 1
NPC1 Niemann-Pick disease, type C1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OSMR oncostatin M receptor
PHF3 PHD finger protein 3
PLCG1 phospholipase C, gamma 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLSCR3 phospholipid scramblase 3
PLSCR4 phospholipid scramblase 4
PLXND1 plexin D1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTCRA pre T-cell antigen receptor alpha
PTHLH parathyroid hormone-like hormone
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPS9 ribosomal protein S9
RYR2 ryanodine receptor 2 (cardiac)
S100A11 S100 calcium binding protein A11
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG5 SMG5 nonsense mediated mRNA decay factor
SOAT1 sterol O-acyltransferase 1
SOCS6 suppressor of cytokine signaling 6
SPATA6 spermatogenesis associated 6
SRSF1 serine/arginine-rich splicing factor 1
STON1 stonin 1
STX16 syntaxin 16
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAPBP TAP binding protein (tapasin)
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TLE4 transducin-like enhancer of split 4
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM259 transmembrane protein 259
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TUBB2B tubulin, beta 2B class IIb
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YIPF4 Yip1 domain family, member 4
ZNF384 zinc finger protein 384
ZNF573 zinc finger protein 573
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASB13 ankyrin repeat and SOCS box containing 13
C16ORF45 chromosome 16 open reading frame 45
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C1QTNF1 C1q and tumor necrosis factor related protein 1
CARD8 caspase recruitment domain family, member 8
CCDC85C coiled-coil domain containing 85C
CCNE1 cyclin E1
CCNT1 cyclin T1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDIP1 cell death-inducing p53 target 1
CENPT centromere protein T
COPS7B COP9 signalosome subunit 7B
CUEDC1 CUE domain containing 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPTOR DEP domain containing MTOR-interacting protein
DMTN dematin actin binding protein
DTX2 deltex 2, E3 ubiquitin ligase
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGLN2 egl-9 family hypoxia-inducible factor 2
ELP6 elongator acetyltransferase complex subunit 6
FAM86C1 family with sequence similarity 86, member C1
FBXL7 F-box and leucine-rich repeat protein 7
FURIN furin (paired basic amino acid cleaving enzyme)
GEMIN4 gem (nuclear organelle) associated protein 4
GLS2 glutaminase 2 (liver, mitochondrial)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1T histone cluster 1, H1t
HIST1H2AI histone cluster 1, H2ai
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOMER2 homer scaffolding protein 2
HOXA2 homeobox A2
IL17RA interleukin 17 receptor A
IRF1 interferon regulatory factor 1
KRT33A keratin 33A, type I
LAMA5 laminin, alpha 5
LAMC3 laminin, gamma 3
LYPD1 LY6/PLAUR domain containing 1
LYPD3 LY6/PLAUR domain containing 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MON1B MON1 secretory trafficking family member B
MPP1 membrane protein, palmitoylated 1, 55kDa
MSX1 msh homeobox 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NINJ1 ninjurin 1
NOL12 nucleolar protein 12
NOTCH1 notch 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
ODF2 outer dense fiber of sperm tails 2
PEX26 peroxisomal biogenesis factor 26
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
POMT1 protein-O-mannosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKX protein kinase, X-linked
PRR15L proline rich 15-like
PSKH1 protein serine kinase H1
PTDSS2 phosphatidylserine synthase 2
PXDC1 PX domain containing 1
RGS20 regulator of G-protein signaling 20
RPH3AL rabphilin 3A-like (without C2 domains)
RUSC2 RUN and SH3 domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH3GL2 SH3-domain GRB2-like 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMA4 glucuronidase, beta pseudogene
SNTA1 syntrophin, alpha 1
SOX12 SRY (sex determining region Y)-box 12
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP4 STEAP family member 4
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TGFBI transforming growth factor, beta-induced, 68kDa
THAP7 THAP domain containing 7
TRIM66 tripartite motif containing 66
TSPAN8 tetraspanin 8
TUBG2 tubulin, gamma 2
UBTF upstream binding transcription factor, RNA polymerase I
VEGFB vascular endothelial growth factor B
XAB2 XPA binding protein 2
YY2 YY2 transcription factor
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZNF696 zinc finger protein 696
ZNF721 zinc finger protein 721