Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the nordihydroguaiaretic acid-1223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
ABHD3 | abhydrolase domain containing 3 |
ACSL5 | acyl-CoA synthetase long-chain family member 5 |
ADK | adenosine kinase |
ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
AZI2 | 5-azacytidine induced 2 |
BAX | BCL2-associated X protein |
BLZF1 | basic leucine zipper nuclear factor 1 |
BMP2K | BMP2 inducible kinase |
C1S | complement component 1, s subcomponent |
C9ORF156 | chromosome 9 open reading frame 156 |
C9ORF40 | chromosome 9 open reading frame 40 |
CALR | calreticulin |
CCNJ | cyclin J |
COPS8 | COP9 signalosome subunit 8 |
CRELD1 | cysteine-rich with EGF-like domains 1 |
CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
DAZAP2 | DAZ associated protein 2 |
DDIT3 | DNA-damage-inducible transcript 3 |
DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
DHODH | dihydroorotate dehydrogenase (quinone) |
DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
DNAH3 | dynein, axonemal, heavy chain 3 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DTWD1 | DTW domain containing 1 |
EID1 | EP300 interacting inhibitor of differentiation 1 |
ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
ERAP1 | endoplasmic reticulum aminopeptidase 1 |
ERO1L | ERO1-like (S. cerevisiae) |
ESRRA | estrogen-related receptor alpha |
FADS2 | fatty acid desaturase 2 |
FAM174B | family with sequence similarity 174, member B |
FAS | Fas cell surface death receptor |
FGF2 | fibroblast growth factor 2 (basic) |
FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
GLRX | glutaredoxin (thioltransferase) |
GOSR2 | golgi SNAP receptor complex member 2 |
HAPLN1 | hyaluronan and proteoglycan link protein 1 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMOX1 | heme oxygenase 1 |
HPS1 | Hermansky-Pudlak syndrome 1 |
INO80B | INO80 complex subunit B |
KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
KDM4A | lysine (K)-specific demethylase 4A |
KDM7A | lysine (K)-specific demethylase 7A |
KLF5 | Kruppel-like factor 5 (intestinal) |
LOX | lysyl oxidase |
MAP9 | microtubule-associated protein 9 |
MARS | methionyl-tRNA synthetase |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NOX1 | NADPH oxidase 1 |
NPC1 | Niemann-Pick disease, type C1 |
NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
OSMR | oncostatin M receptor |
PHF3 | PHD finger protein 3 |
PLCG1 | phospholipase C, gamma 1 |
PLD1 | phospholipase D1, phosphatidylcholine-specific |
PLSCR3 | phospholipid scramblase 3 |
PLSCR4 | phospholipid scramblase 4 |
PLXND1 | plexin D1 |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
PTCRA | pre T-cell antigen receptor alpha |
PTHLH | parathyroid hormone-like hormone |
RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
RPS9 | ribosomal protein S9 |
RYR2 | ryanodine receptor 2 (cardiac) |
S100A11 | S100 calcium binding protein A11 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SMG5 | SMG5 nonsense mediated mRNA decay factor |
SOAT1 | sterol O-acyltransferase 1 |
SOCS6 | suppressor of cytokine signaling 6 |
SPATA6 | spermatogenesis associated 6 |
SRSF1 | serine/arginine-rich splicing factor 1 |
STON1 | stonin 1 |
STX16 | syntaxin 16 |
SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
TAPBP | TAP binding protein (tapasin) |
TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
TLE4 | transducin-like enhancer of split 4 |
TMED7 | transmembrane emp24 protein transport domain containing 7 |
TMEM259 | transmembrane protein 259 |
TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
TUBB2B | tubulin, beta 2B class IIb |
TWISTNB | TWIST neighbor |
XDH | xanthine dehydrogenase |
XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
YIPF4 | Yip1 domain family, member 4 |
ZNF384 | zinc finger protein 384 |
ZNF573 | zinc finger protein 573 |
ZNF76 | zinc finger protein 76 |
ZNF862 | zinc finger protein 862 |
Symbol | Name |
---|---|
ADCY6 | adenylate cyclase 6 |
ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
ASB13 | ankyrin repeat and SOCS box containing 13 |
C16ORF45 | chromosome 16 open reading frame 45 |
C16ORF59 | chromosome 16 open reading frame 59 |
C17ORF70 | chromosome 17 open reading frame 70 |
C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
CARD8 | caspase recruitment domain family, member 8 |
CCDC85C | coiled-coil domain containing 85C |
CCNE1 | cyclin E1 |
CCNT1 | cyclin T1 |
CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
CDIP1 | cell death-inducing p53 target 1 |
CENPT | centromere protein T |
COPS7B | COP9 signalosome subunit 7B |
CUEDC1 | CUE domain containing 1 |
DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
DEPTOR | DEP domain containing MTOR-interacting protein |
DMTN | dematin actin binding protein |
DTX2 | deltex 2, E3 ubiquitin ligase |
DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
EGLN2 | egl-9 family hypoxia-inducible factor 2 |
ELP6 | elongator acetyltransferase complex subunit 6 |
FAM86C1 | family with sequence similarity 86, member C1 |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FURIN | furin (paired basic amino acid cleaving enzyme) |
GEMIN4 | gem (nuclear organelle) associated protein 4 |
GLS2 | glutaminase 2 (liver, mitochondrial) |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
HIST1H1T | histone cluster 1, H1t |
HIST1H2AI | histone cluster 1, H2ai |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
HOMER2 | homer scaffolding protein 2 |
HOXA2 | homeobox A2 |
IL17RA | interleukin 17 receptor A |
IRF1 | interferon regulatory factor 1 |
KRT33A | keratin 33A, type I |
LAMA5 | laminin, alpha 5 |
LAMC3 | laminin, gamma 3 |
LYPD1 | LY6/PLAUR domain containing 1 |
LYPD3 | LY6/PLAUR domain containing 3 |
MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
MON1B | MON1 secretory trafficking family member B |
MPP1 | membrane protein, palmitoylated 1, 55kDa |
MSX1 | msh homeobox 1 |
MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
NINJ1 | ninjurin 1 |
NOL12 | nucleolar protein 12 |
NOTCH1 | notch 1 |
NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
ODF2 | outer dense fiber of sperm tails 2 |
PEX26 | peroxisomal biogenesis factor 26 |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
POLE | polymerase (DNA directed), epsilon, catalytic subunit |
POMT1 | protein-O-mannosyltransferase 1 |
POMT2 | protein-O-mannosyltransferase 2 |
PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
PRKX | protein kinase, X-linked |
PRR15L | proline rich 15-like |
PSKH1 | protein serine kinase H1 |
PTDSS2 | phosphatidylserine synthase 2 |
PXDC1 | PX domain containing 1 |
RGS20 | regulator of G-protein signaling 20 |
RPH3AL | rabphilin 3A-like (without C2 domains) |
RUSC2 | RUN and SH3 domain containing 2 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
SH3GL2 | SH3-domain GRB2-like 2 |
SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
SMA4 | glucuronidase, beta pseudogene |
SNTA1 | syntrophin, alpha 1 |
SOX12 | SRY (sex determining region Y)-box 12 |
STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
STEAP4 | STEAP family member 4 |
STK16 | serine/threonine kinase 16 |
STX1A | syntaxin 1A (brain) |
SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
TGFBI | transforming growth factor, beta-induced, 68kDa |
THAP7 | THAP domain containing 7 |
TRIM66 | tripartite motif containing 66 |
TSPAN8 | tetraspanin 8 |
TUBG2 | tubulin, gamma 2 |
UBTF | upstream binding transcription factor, RNA polymerase I |
VEGFB | vascular endothelial growth factor B |
XAB2 | XPA binding protein 2 |
YY2 | YY2 transcription factor |
ZNF324 | zinc finger protein 324 |
ZNF34 | zinc finger protein 34 |
ZNF408 | zinc finger protein 408 |
ZNF574 | zinc finger protein 574 |
ZNF696 | zinc finger protein 696 |
ZNF721 | zinc finger protein 721 |